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Journal of Cellular Biochemistry, ISSN 0730-2312, 08/2018, Volume 119, Issue 8, pp. 6633 - 6643
Protein phosphatase 2A (PP2A) is an important enzyme within various signal transduction pathways. The present study was investigated PP2A mediates JS‐K‐induced... 
apoptosis | JS‐K | nitric oxide | protein phosphatase 2A | hepatocellular carcinoma | JS-K | ACTIVATION | NITRIC-OXIDE PRODRUG | DONOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | PP2A | CIP2A | CELL BIOLOGY | BAX | NITRATION | LIFE | Cell Survival - drug effects | Liver Neoplasms - genetics | Apoptosis - drug effects | Humans | Liver Neoplasms - drug therapy | Protein Phosphatase 2 - genetics | bcl-X Protein - genetics | Piperazines - pharmacology | Proto-Oncogene Proteins c-bcl-2 - biosynthesis | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Hep G2 Cells | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - biosynthesis | Protein Phosphatase 2 - metabolism | Liver Neoplasms - pathology | bcl-X Protein - biosynthesis | Gene Expression Regulation, Neoplastic - drug effects | Azo Compounds - pharmacology | Proto-Oncogene Proteins c-bcl-2 - genetics | Carcinoma, Hepatocellular - metabolism | Proteins | Phosphatases | Apoptosis | Cytochrome | Bax protein | Phosphoprotein phosphatase | Toxicity | Caspase | Cytotoxicity | Hepatocellular carcinoma | Activation | siRNA | Phosphatase | BAK protein | Cytochrome c | Time dependence | Signal transduction | Reduction | Mitochondria | Cell lines | Transduction | Protein phosphatase | Membrane potential | Viability | BIM protein
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 11/2018, Volume 107, pp. 1385 - 1392
JS-K, (O -(2, 4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen 1-ium-1, 2-diolate), is a novel diazeniumdiolate-based nitric oxide donor prodrug.... 
Reactive oxygen species | JS-K | Apoptosis | Mitochondrial membrane motential | MEDICINE, RESEARCH & EXPERIMENTAL | ACTIVATION | VIVO | LUNG-CANCER CELLS | RELEASE | DAMAGE | IN-VITRO | HEPATOCELLULAR-CARCINOMA | PRODRUG | PHARMACOLOGY & PHARMACY
Journal Article
Oncology Letters, ISSN 1792-1074, 03/2017, Volume 13, Issue 3, pp. 1137 - 1142
Reactive oxygen species (ROS) are chemical species that alter redox status, and are responsible for inducing carcinogenesis. The purpose of the present study... 
Prostate cancer cells | Reactive oxygen species | JS-K | Nitric oxide | Apoptosis | OXYGEN SPECIES ROS | IN-VITRO | VIVO | ONCOLOGY | DNA-DAMAGE
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 07/2018, Volume 37, Issue 1, pp. 142 - 15
Background: JS-K is a nitric oxide (NO) donor and could generate intracellularly high levels of NO. The study explores PP2A as a tumor suppressor is a major... 
Hepatocellular carcinoma | JS-K | Nitric oxide | Apoptosis | Protein phosphatase 2A | PATHWAYS | NITRIC-OXIDE PRODRUG | PHOSPHORYLATION | DONOR | PP2A | CANCER | REGULATOR | ONCOLOGY | Phosphatases | Physiological aspects | Development and progression | Genetic aspects | Research | Hepatoma | Proteins | Liver cancer | Phosphorylation | Cell growth | Rodents | Cytotoxicity | Physiology | Phosphatase | Kinases | Prostate cancer
Journal Article
Biomedicine & Pharmacotherapy, ISSN 0753-3322, 11/2018, Volume 107, p. 1385
JS-K, (O.sup.2-(2, 4-dinitrophenyl) 1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen 1-ium-1, 2-diolate), is a novel diazeniumdiolate-based nitric oxide donor... 
Cytochrome c | Antioxidants | Nitric oxide | Apoptosis
Journal Article
Journal Article
Chinese Journal of Pharmacology and Toxicology, ISSN 1000-3002, 07/2017, Volume 31, Issue 7, pp. 730 - 735
Journal Article
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), ISSN 0302-9743, 2018, Volume 11335, pp. 354 - 366
Conference Proceeding
Zhongguo Yaolixue yu Dulixue Zazhi = Chinese Journal of Pharmacology and Toxicology, ISSN 1000-3002, 01/2017, Volume 31, Issue 7, p. 730
OBJECTIVE To investigate the regulation of{O2 (2,4-dinitrophenyl)1-[(4-ethoxycarbonyl) piperazin-1-yl] diazen-1-ium-1, 2-diolate} (JS-K), a nitric oxide donor,... 
Energy metabolism | Hypoxia-inducible factor 1 | Succinate dehydrogenase | Pyruvic acid | Colorimetry | Hepatoma | Western blotting | Bearing | Thymus | Hypoxia-inducible factor 1a | Oxidation | Phosphofructokinase | Adenosine triphosphate | Hypoxia-inducible factors | Spleen | Pyruvate kinase | Metabolism | Hexokinase | Nitric oxide | Glycolysis | Hypoxia | Mice | Lactic acid | ATP | Adenosine triphosphatase | Tumors | Peritoneum
Journal Article
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 11/2018, Volume 107, p. 1385
Journal Article
无线互联科技, ISSN 1672-6944, 2017, Issue 16, pp. 65 - 66
电商行业想要通过高效的互联网络提高办事效率、降低开销成本、方便管理人员管理,利用软件工程的设计方法和先进的软件开发框架来实现电子商务管理势在必行。文章主要对JS下电商管理系统的设计及实现进行了探讨,以期为电商管理系统的建设提供参考。 
设计 | 电商管理系统 | JS | 实现
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2018, Volume 143, pp. 732 - 744
A series of O -(2,4-dinitrophenyl)diazeniumdiolates derivatives were designed, synthesized and antiproliferative activities evaluated as novel nitric oxide... 
Diazeniumdiolates | No-Releasing | JS-K | Adriamycin | Multidrug resistance | Index Medicus
Journal Article
by 陈晨
知识管理论坛, ISSN 2095-5472, 2015, Issue 3, pp. 37 - 44
通过探索微信JS-SDK的移动端开发,搭建一个可交互、富功能的移动社交图书馆服务系统,并满足图书馆移动端日益增长的用户需求。以微信JS-SDK为核心,基于HTML 5和CSS... 
图书馆;微信;微信公众平台;JS-SDK
Journal Article
Journal of Asian Natural Products Research, ISSN 1028-6020, 08/2010, Volume 12, Issue 8, pp. 672 - 679
Journal Article
by Klionsky, Daniel J and Abdelmohsen, Kotb and Abe, Akihisa and Abedin, Md Joynal and Abeliovich, Hagai and Acevedo Arozena, Abraham and Adachi, Hiroaki and Adams, Christopher M and Adams, Peter D and Adeli, Khosrow and Adhihetty, Peter J and Adler, Sharon G and Agam, Galila and Agarwal, Rajesh and Aghi, Manish K and Agnello, Maria and Agostinis, Patrizia and Aguilar, Patricia V and Aguirre-Ghiso, Julio and Airoldi, Edoardo M and Ait-Si-Ali, Slimane and Akematsu, Takahiko and Akporiaye, Emmanuel T and Al-Rubeai, Mohamed and Albaiceta, Guillermo M and Albanese, Chris and Albani, Diego and Albert, Matthew L and Aldudo, Jesus and Algül, Hana and Alirezaei, Mehrdad and Alloza, Iraide and Almasan, Alexandru and Almonte-Beceril, Maylin and Alnemri, Emad S and Alonso, Covadonga and Altan-Bonnet, Nihal and Altieri, Dario C and Alvarez, Silvia and Alvarez-Erviti, Lydia and Alves, Sandro and Amadoro, Giuseppina and Amano, Atsuo and Amantini, Consuelo and Ambrosio, Santiago and Amelio, Ivano and Amer, Amal O and Amessou, Mohamed and Amon, Angelika and An, Zhenyi and Anania, Frank A and Andersen, Stig U and Andley, Usha P and Andreadi, Catherine K and Andrieu-Abadie, Nathalie and Anel, Alberto and Ann, David K and Anoopkumar-Dukie, Shailendra and Antonioli, Manuela and Aoki, Hiroshi and Apostolova, Nadezda and Aquila, Saveria and Aquilano, Katia and Araki, Koichi and Arama, Eli and Aranda, Agustin and Araya, Jun and Arcaro, Alexandre and Arias, Esperanza and Arimoto, Hirokazu and Ariosa, Aileen R and Armstrong, Jane L and Arnould, Thierry and Arsov, Ivica and Asanuma, Katsuhiko and Askanas, Valerie and Asselin, Eric and Atarashi, Ryuichiro and Atherton, Sally S and Atkin, Julie D and Attardi, Laura D and Auberger, Patrick and Auburger, Georg and Aurelian, Laure and Autelli, Riccardo and Avagliano, Laura and Avantaggiati, Maria Laura and Avrahami, Limor and Awale, Suresh and Azad, Neelam and Bachetti, Tiziana and Backer, Jonathan M and Bae, Dong-Hun and Bae, Jae-sung and Bae, Ok-Nam and Bae, Soo Han and Baehrecke, Eric H and Baek, Seung-Hoon and Baghdiguian, Stephen and Bagniewska-Zadworna, Agnieszka and ... and Medicinska fakulteten and Region Östergötland and Linköpings universitet and Institutionen för klinisk och experimentell medicin and Diagnostikcentrum and Klinisk patologi och klinisk genetik and Institutionen för medicin och hälsa and Avdelningen för läkemedelsforskning and Avdelningen för cellbiologi
Autophagy, ISSN 1554-8627, 01/2016, Volume 12, Issue 1, pp. 1 - 222
Journal Article