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Food & Function, ISSN 2042-6496, 05/2017, Volume 8, Issue 5, pp. 1785 - 1792
This study was designed to investigate the effects of polydatin (PLD) on potassium oxonate-induced hyperuricemic rats. Hyperuricemic rats were treated with... 
Journal Article
NeuroToxicology, ISSN 0161-813X, 01/2012, Volume 33, Issue 1, pp. 59 - 69
Glutamate is considered to be responsible for the pathogenesis of cerebral ischemia disease. [Ca ] influx and reactive oxygen species (ROS) production are... 
PC 12 cells | Bax protein | Bcl-2 protein | Caspase-3 protein | ROS | Ginkgolide K
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 07/2018, Volume 22, Issue 7, pp. 3691 - 3697
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 12/2017, Volume 21, Issue 12, pp. 3178 - 3189
The purpose of the present study was to investigate the effect of salidroside (Sal) on myocardial injury in lipopolysaccharide ( LPS )‐induced endotoxemic in... 
H9C2 | myocardial injury | ROS | mTOR | salidroside | 3K/Akt | LPS | PI3K/Akt/mTOR | MEDICINE, RESEARCH & EXPERIMENTAL | OXIDATIVE STRESS | PHOSPHATIDYLINOSITOL 3-KINASE | RATS | ACUTE LUNG INJURY | ISCHEMIA REPERFUSION INJURY | NLRP3 INFLAMMASOME | CELL BIOLOGY | MITOCHONDRIAL ROS | SIGNALING PATHWAY | TANSHINONE IIA SULFONATE | KAPPA-B PATHWAY | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | TOR Serine-Threonine Kinases - metabolism | Tumor Necrosis Factor-alpha - genetics | Endotoxemia - chemically induced | Endotoxemia - pathology | Interleukin-1beta - genetics | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Lipopolysaccharides | Myocardial Reperfusion Injury - pathology | Dexamethasone - pharmacology | TOR Serine-Threonine Kinases - genetics | Interleukin-1beta - metabolism | Myocardium - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Interleukin-6 - metabolism | Myocardial Reperfusion Injury - genetics | Phenols - pharmacology | Glutathione Peroxidase - metabolism | Interleukin-6 - genetics | Signal Transduction | Catalase - genetics | Endotoxemia - drug therapy | Rats | Cardiotonic Agents - pharmacology | Rats, Sprague-Dawley | Glutathione Peroxidase - genetics | Myocytes, Cardiac - pathology | Reactive Oxygen Species - antagonists & inhibitors | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - metabolism | Hemodynamics - drug effects | Nitric Oxide Synthase Type II - metabolism | Tumor Necrosis Factor-alpha - metabolism | Endotoxemia - genetics | Glutathione - metabolism | Myocardial Reperfusion Injury - chemically induced | Phosphatidylinositol 3-Kinases - metabolism | Proto-Oncogene Proteins c-akt - genetics | TOR Serine-Threonine Kinases - antagonists & inhibitors | Myocardial Reperfusion Injury - drug therapy | Superoxide Dismutase - metabolism | Cell Line | Glucosides - pharmacology | Gene Expression Regulation | Myocardium - pathology | Catalase - metabolism | Phosphatidylinositol 3-Kinases - genetics | Animals | Nitric Oxide Synthase Type II - genetics | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Mitogens | Cysteine | PI3K | Akt | Original
Journal Article
Journal Article
International Immunopharmacology, ISSN 1567-5769, 02/2018, Volume 55, pp. 55 - 62
The current study was designed to investigate the hepatoprotective effects and possible mechanisms of Baicalein (BA) on the diabetic liver injury and . The... 
Baicalein | Inflammation | HMGB1/TLR4/NF-κB | Liver injury | METFORMIN | OXIDATIVE STRESS | ACTIVATION | HYPERLIPIDEMIA | HMGB1/TLR4/NF-kappa B | RATS | INJURY | MECHANISMS | MODEL | HMGB1 | IMMUNOLOGY | PHARMACOLOGY & PHARMACY | COMPLICATIONS
Journal Article
IUBMB Life, ISSN 1521-6543, 06/2016, Volume 68, Issue 6, pp. 429 - 435
Journal Article
Planta Medica, ISSN 0032-0943, 05/2013, Volume 79, Issue 8, pp. 634 - 638
Journal Article
Journal Article
Journal Article
Planta Medica, ISSN 0032-0943, 11/2011, Volume 77, Issue 16, pp. 1769 - 1773
Abstract Astilbin is a flavonoid compound isolated from the rhizome of SMILAX CHINA L. The effects and possible mechanisms of astilbin on hyperuricemia and... 
Biological and Pharmacological Activity | connective tissue growth factor | hyperuricemia | interleukin-1 | Smilaceae | astilbin | Smilax china | nephropathy | TISSUE-GROWTH-FACTOR | CHEMISTRY, MEDICINAL | GOUT | INJURY | FLAVONOIDS | PLANT SCIENCES | ALLOPURINOL | CRYSTALS | PHARMACOLOGY & PHARMACY | MICE | KIDNEY | URIC-ACID | Connective tissues | Hyperuricemia | Care and treatment | Interleukin-1 | Usage | Research | Sarsaparilla
Journal Article
Environmental Toxicology and Pharmacology, ISSN 1382-6689, 2011, Volume 31, Issue 3, pp. 443 - 452
Abstract Radix Salvia miltiorrhiza (RSM), a traditional Chinese medicinal herb, has been alleged to possess therapeutic effects against senile dementia, also... 
Emergency | Acetylcholinesterase | Radix Salvia miltiorrhiza | Amyloid β | PROTEIN | INDUCED APOPTOSIS | ALZHEIMERS-DISEASE | ANTIOXIDANT ACTIVITIES | RAT CORONARY-ARTERY | BUNGE | ENVIRONMENTAL SCIENCES | Amyloid beta | CALCIUM-CHANNELS | LIVER-INJURY | PHARMACOLOGY & PHARMACY | TOXICOLOGY | CHINESE MEDICINAL PREPARATIONS | EXTRACT | L-Lactate Dehydrogenase - metabolism | Neuroprotective Agents | Apoptosis - drug effects | Calcium - metabolism | Plant Extracts - pharmacology | Polyphenols - pharmacology | Benzofurans - pharmacology | Male | PC12 Cells | Tetrazolium Salts | Hydroxybenzoates - pharmacology | Hydroxybenzoates - chemistry | Thiazoles | Phosphatidylinositols - metabolism | Cell Survival - drug effects | Polyphenols - isolation & purification | Cholinesterase Inhibitors | Amyloid beta-Peptides - toxicity | Diterpenes, Abietane - chemistry | Rats | Antioxidants - pharmacology | Rats, Sprague-Dawley | Amyloid beta-Peptides - antagonists & inhibitors | Diterpenes, Abietane - pharmacology | Salvia miltiorrhiza - chemistry | Animals | Herbs | Brain | Enzymes | Ethanol | Neurodegenerative diseases | Toxicity | Herbal medicines | phenolic compounds | Cytotoxicity | beta -Amyloid | L-Lactate dehydrogenase | tanshinones | phenolic acids | Dementia disorders | Polyphenols | Amyloid | Alzheimer's disease | Apoptosis
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 05/2012, Volume 141, Issue 1, pp. 386 - 395
Danggui-Shaoyao-San (DSS), a famous traditional Chinese medicine formula consisting of six herbal medicines, has been used to treat gynecological disorders and... 
Oxidative stress | Neuronal apoptosis | d-Galactose | Danggui-Shaoyao-San | AQUEOUS EXTRACT | CHEMISTRY, MEDICINAL | ALZHEIMERS-DISEASE | RAT CORTICAL-NEURONS | CHINESE MEDICINE | Z-LIGUSTILIDE | PLANT SCIENCES | CYTOCHROME-C | INTEGRATIVE & COMPLEMENTARY MEDICINE | TOKI-SHAKUYAKU-SAN | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | PC12 CELLS | D-Galactose | BRAIN | Immunohistochemistry | Neurons - pathology | Apoptosis - drug effects | Glutathione - metabolism | Cognition Disorders - chemically induced | Caspase 3 - metabolism | Drugs, Chinese Herbal - pharmacology | Cognition Disorders - metabolism | Male | Chromatography, High Pressure Liquid | Hippocampus - drug effects | Protein Carbonylation - drug effects | Dose-Response Relationship, Drug | Proto-Oncogene Proteins c-bcl-2 - metabolism | Cognition Disorders - prevention & control | Neuroprotective Agents - pharmacology | Time Factors | Cellular Senescence | Behavior, Animal - drug effects | Neurons - metabolism | Phytotherapy | Neurons - drug effects | Superoxide Dismutase - metabolism | Cognition Disorders - psychology | Disease Models, Animal | Malondialdehyde - metabolism | Cognition Disorders - pathology | bcl-2-Associated X Protein - metabolism | Hippocampus - pathology | Antioxidants - pharmacology | Cognition - drug effects | Mice, Inbred ICR | Hippocampus - metabolism | Animals | Mice | Nitric Oxide Synthase - metabolism | Oxidative Stress - drug effects | Galactose | Nitric Oxide - metabolism | Nootropic Agents - pharmacology | Plants, Medicinal | Nitrogen oxide | Neurons | Nitric oxide | Genes | Superoxide | Medicine, Chinese | Lymphomas | Cognition | Apoptosis | Brain | Neuroprotection | Bax protein | Bcl-2 protein | Ethanol | Herbal medicines | Cognitive ability | Superoxide dismutase | Caspase-3 | Malondialdehyde | Nitric-oxide synthase | Traditional Chinese Medicine | Aging | Hippocampus | Glutathione
Journal Article