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1. Full Text Are Physical Activity Associations with Bone Mineral Density Modified by Metabolic Traits?
by BUTTAN, ANSHU and GUO, XIUQING and IDA CHEN, YII-DER and HSUEH, WILLA and ROTTER, JEROME I and GOODARZI, MARK O
Diabetes, ISSN 0012-1797, 05/2018, Volume 67, Issue Supplement 1, p. 2244
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2. Full Text Reply
by Nannini, Drew and Torres, Mina and Chen, Yii-Der I and Taylor, Kent D and Rotter, Jerome I and Varma, Rohit and Gao, Xiaoyi
Ophthalmology, ISSN 0161-6420, 04/2016, Volume 123, Issue 4, pp. e31 - e32
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3. Full Text Reply
by Nannini, Drew and Torres, Mina and Chen, Yii-Der I and Taylor, Kent D and Rotter, Jerome I and Varma, Rohit and Gao, Xiaoyi
Ophthalmology, ISSN 0161-6420, 04/2016, Volume 123, Issue 4, pp. e31 - e32
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4. Full Text Reply
by Nannini, Drew and Torres, Mina and Chen, Yii-Der I and Taylor, Kent D and Rotter, Jerome I and Varma, Rohit and Gao, Xiaoyi
Ophthalmology, ISSN 0161-6420, 04/2016, Volume 123, Issue 4, pp. e31 - e32
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5. Full Text Reply
by Nannini, Drew and Torres, Mina and Chen, Yii-Der I and Taylor, Kent D and Rotter, Jerome I and Varma, Rohit and Gao, Xiaoyi
Ophthalmology, ISSN 0161-6420, 04/2016, Volume 123, Issue 4, p. e31-e32
Research institutes | Ophthalmology
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6. Full Text Classification of Type 2 Diabetes Genetic Variants and a Novel Genetic Risk Score Association with Insulin Clearance
by Goodarzi, Mark O and Palmer, Nicholette D and Cui, Jinrui and Guo, Xiuqing and Chen, Yii-Der I and Taylor, Kent D and Raffel, Leslie J and Wagenknecht, Lynne E and Buchanan, Thomas A and Hsueh, Willa A and Rotter, Jerome I
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 11/2019
Abstract Context Genome-wide association studies have identified >450 single nucleotide polymorphisms (SNPs) for type 2 diabetes (T2D). Objective To facilitate... 
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7. Full Text Targeting inflammation using salsalate in patientswith type 2 diabetes: Effects on flow-mediated dilation (TINSAL-FMD)
by Goldfine, Allison B and Stewart Buck, J and Desouza, Cyrus and Fonseca, Vivian and Chen, Yii-Der Ida and Shoelson, Steven E and Jablonski, Kathleen A and Creager, Mark A
Diabetes Care, ISSN 0149-5992, 12/2013, Volume 36, Issue 12, pp. 4132 - 4139
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8. Full Text Reply
by Nannini, Drew, MA, MS and Torres, Mina, MS and Chen, Yii-Der I., PhD and Taylor, Kent D., PhD and Rotter, Jerome I., MD and Varma, Rohit, MD, MPH and Gao, Xiaoyi, PhD
Ophthalmology, ISSN 0161-6420, 2016, Volume 123, Issue 4, pp. e31 - e32
Ophthalmology
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9. Full Text Adiponectin Isoform Patterns in Ethnic‐Specific ADIPOQ Mutation Carriers: The IRAS Family Study
by Tabb, Keri L and Gao, Chuan and Hicks, Pamela J and Hawkins, Gregory A and Rotter, Jerome I and Chen, Yii‐Der Ida and Guo, Xiuqing and Norris, Jill M and Lorenzo, Carlos and Freedman, Barry I and Bowden, Donald W and Palmer, Nicholette D
Obesity, ISSN 1930-7381, 08/2017, Volume 25, Issue 8, pp. 1384 - 1390
Objective Adiponectin is found in human serum in three groups of multimers (high molecular weight [HMW], medium molecular weight [MMW], and low molecular... 
OBESITY | NUTRITION & DIETETICS | PROTEIN | PLASMA | GENE | INSULIN-RESISTANCE | IMAGE-ANALYSIS | ENDOCRINOLOGY & METABOLISM | SENSITIVITY | AFRICAN-AMERICANS | LINKAGE | ASSOCIATION | Hispanic Americans - genetics | Molecular Weight | Atherosclerosis - genetics | Humans | Mice, Inbred C57BL | Middle Aged | Insulin Resistance | African Americans - genetics | Male | Adiponectin - blood | Atherosclerosis - blood | Protein Isoforms - blood | Young Adult | Animals | Adiponectin - genetics | Adult | Female | Aged | Mice | Mutation | Protein Isoforms - genetics | Obesity | Rodents | Hispanic Americans | Atherosclerosis | African Americans | Insulin resistance | Diabetes | Adipocytes | Metabolic syndrome | Ethnic Minorities | Adipokines | Hispanics | Family Studies | African American
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10. Full Text Genome-wide association study identifiesWNT7Bas a novel locus for central corneal thickness in Latinos
by Gao, Xiaoyi and Nannini, Drew R and Corrao, Kristen and Torres, Mina and Chen, Yii-Der I and Fan, Bao J and Wiggs, Janey L and Taylor, Kent D and Gauderman, W. James and Rotter, Jerome I and Varma, Rohit and International Glaucoma Genetics Consortium
Human Molecular Genetics, ISSN 0964-6906, 09/2016, p. ddw319
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11. Full Text Branched-chain amino acids and insulin metabolism: The Insulin Resistance Atherosclerosis Study (IRAS)
by Lee, C. Christine and Watkins, Steve M and Lorenzo, Carlos and Wagenknecht, Lynne E and Il'Yasova, Dora and Chen, Yii-Der I and Haffner, Steven M and Hanley, Anthony J
Diabetes Care, ISSN 0149-5992, 04/2016, Volume 39, Issue 4, pp. 582 - 588
Recent studies using untargeted metabolomics approaches have suggested that plasma branched-chain amino acids (BCAAs) are associated with incident diabetes.... 
Multivariate Analysis | Glucose Tolerance Test | Follow-Up Studies | Humans | Middle Aged | Hispanic Americans | Insulin Resistance | African Americans | European Continental Ancestry Group | Linear Models | Male | Diabetes Mellitus, Type 2 - metabolism | Insulin - blood | Incidence | Atherosclerosis - blood | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Female | Amino Acids, Branched-Chain - blood | Cohort Studies | Care and treatment | Analysis | Atherosclerosis | Influence | Insulin resistance | Dosage and administration | Diabetes | Insulin | Epidemiology | Health Services Research
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12. Full Text The triglyceride to high-density lipoprotein cholesterol ratio as a predictor of insulin resistance, [beta]-cell function, and diabetes in Hispanics and African Americans
by Young, Kendra A and Maturu, Amita and Lorenzo, Carlos and Langefeld, Carl D and Wagenknecht, Lynne E and Chen, Yii-Der I and Taylor, Kent D and Rotter, Jerome I and Norris, Jill M and Rasouli, Neda
Journal of Diabetes and Its Complications, ISSN 1056-8727, 02/2019, Volume 33, Issue 2, p. 118
The TG/HDL-C ratio is used as a marker of insulin resistance (IR) in Caucasians; however, there is limited data in other ethnic groups. We hypothesized that... 
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13. Full Text Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease
by Dewey, Frederick E and Gusarova, Viktoria and Dunbar, Richard L and O’Dushlaine, Colm and Schurmann, Claudia and Gottesman, Omri and McCarthy, Shane and Van Hout, Cristopher V and Bruse, Shannon and Dansky, Hayes M and Leader, Joseph B and Murray, Michael F and Ritchie, Marylyn D and Kirchner, H. Lester and Habegger, Lukas and Lopez, Alex and Penn, John and Zhao, An and Shao, Weiping and Stahl, Neil and Murphy, Andrew J and Hamon, Sara and Bouzelmat, Aurelie and Zhang, Rick and Shumel, Brad and Pordy, Robert and Gipe, Daniel and Herman, Gary A and Sheu, Wayne H.H and Lee, I-Te and Liang, Kae-Woei and Guo, Xiuqing and Rotter, Jerome I and Chen, Yii-Der I and Kraus, William E and Shah, Svati H and Damrauer, Scott and Small, Aeron and Rader, Daniel J and Wulff, Anders Berg and Nordestgaard, Børge G and Tybjærg-Hansen, Anne and van den Hoek, Anita M and Princen, Hans M.G and Ledbetter, David H and Carey, David J and Overton, John D and Reid, Jeffrey G and Sasiela, William J and Banerjee, Poulabi and Shuldiner, Alan R and Borecki, Ingrid B and Teslovich, Tanya M and Yancopoulos, George D and Mellis, Scott J and Gromada, Jesper and Baras, Aris
The New England Journal of Medicine, ISSN 0028-4793, 07/2017, Volume 377, Issue 3, pp. 211 - 221
Loss-of-function variants in ANGPTL3 were associated with lower plasma levels of lipids and lower rates of coronary disease. A monoclonal antibody against... 
MEDICINE, GENERAL & INTERNAL | HEART-DISEASE | REMNANT CHOLESTEROL | PLASMA-LIPIDS | IMMUNOGLOBULIN GENES | ATHEROSCLEROSIS | RISK | CORONARY-ARTERY-DISEASE | FAMILIAL COMBINED HYPOLIPIDEMIA | LIPOPROTEIN-LIPASE GENE | TRANSGENIC MICE | Cardiovascular Diseases - prevention & control | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Male | Angiopoietins - antagonists & inhibitors | Dose-Response Relationship, Drug | Dyslipidemias - blood | Angiopoietin-like Proteins | Lipids - blood | Female | Disease Models, Animal | Dyslipidemias - drug therapy | Atherosclerosis - drug therapy | Double-Blind Method | Antibodies, Monoclonal - pharmacology | Coronary Artery Disease - metabolism | Mice, Inbred Strains | Atherosclerosis - metabolism | Animals | Antibodies, Monoclonal - administration & dosage | Coronary Artery Disease - genetics | Lipid Metabolism - drug effects | Aged | Mice | Mutation | Angiopoietins - genetics | Cholesterol, LDL | Research | Antibiosis | Atherosclerosis | Lipoproteins (low density) | Medical research | Angiopoietin | Genomics | Genes | Coronary artery | Triglycerides | Biochemistry | Gene expression | Cholesterol | Serum levels | Proteins | Antagonism | Arteriosclerosis | Plasma levels | Cardiovascular diseases | Lipoproteins (high density) | Heart diseases | Drug dosages | Pharmaceuticals
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14. Full Text Improved performance of dynamic measures of insulin response over surrogate indices to identify genetic contributors of type 2 diabetes: The GUARDIAN consortium
by Palmer, Nicholette D and Wagenknecht, Lynne E and Langefeld, Carl D and Wang, Nan and Buchanan, Thomas A and Xiang, Anny H and Allayee, Hooman and Bergman, Richard N and Raffel, Leslie J and Chen, Yii-Der Ida and Haritunians, Talin and Fingerlin, Tasha and Goodarzi, Mark O and Taylor, Kent D and Rotter, Jerome I and Watanabe, Richard M and Bowden, Donald W
Diabetes, ISSN 0012-1797, 07/2016, Volume 65, Issue 7, pp. 2072 - 2080
Type 2 diabetes (T2D) is a heterogeneous disorder with contributions from peripheral insulin resistance and beta-cell dysfunction. For minimization of... 
FASTING PLASMA-GLUCOSE | HOMEOSTASIS MODEL ASSESSMENT | NON-HISPANIC WHITES | MINIMAL-MODEL | MEXICAN-AMERICANS | ENDOCRINOLOGY & METABOLISM | SUSCEPTIBILITY LOCI | RESISTANCE ATHEROSCLEROSIS | AFRICAN-AMERICANS | GENOME-WIDE ASSOCIATION | BETA-CELL FUNCTION | Glucose Tolerance Test | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | Insulin - blood | Insulin Resistance - physiology | Homeostasis - physiology | Adult | Female | Aged | Blood Glucose - metabolism | Type 2 diabetes | Care and treatment | Genetic variation | Genetics | Dosage and administration | Research | Insulin | Metabolomics | Genomes | Proteomics
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15. Full Text Association study of androgen signaling pathway genes in polycystic ovary syndrome
by Ketefian, Aline and Jones, Michelle R and Krauss, Ronald M and Chen, Yii-Der I and Legro, Richard S and Azziz, Ricardo and Goodarzi, Mark O
Fertility and Sterility, ISSN 0015-0282, 02/2016, Volume 105, Issue 2, p. 467
To evaluate genes involved in androgen receptor (AR) signaling as candidate genes for polycystic ovary syndrome (PCOS). 
Medical research | Stein-Leventhal syndrome | Genes | Genetic research | Medicine, Experimental | Ovarian cancer
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16. Full Text Biological, clinical and population relevance of 95 loci for blood lipids
by Teslovich, Tanya M and Musunuru, Kiran and Smith, Albert V and Edmondson, Anew C and Stylianou, Ioannis M and Koseki, Masahiro and Pirruccello, James P and Ripatti, Samuli and Chasman, Daniel I and Willer, Cristen J and Johansen, Christopher T and Fouchier, Sigrid W and Isaacs, Aaron and Peloso, Gina M and Barbalic, Maja and Ricketts, Sally L and Bis, Joshua C and Aulchenko, Yurii S and Thorleifsson, Gudmar and Feitosa, Mary F and Chambers, John and Orho-Melander, Marju and Melander, Olle and Johnson, Toby and Li, Xiaohui and Guo, Xiuqing and Li, Mingyao and Shin Cho, Yoon and Jin Go, Min and Jin Kim, Young and Lee, Jong-Young and Park, Taesung and Kim, Kyunga and Sim, Xueling and Twee-Hee Ong, Rick and Croteau-Chonka, Damien C and Lange, Leslie A and Smith, Joshua D and Song, Kijoung and Hua Zhao, Jing and Yuan, Xin and Luan, Jian'an and Lamina, Claudia and Ziegler, Aneas and Zhang, Weihua and Zee, Robert Y. L and Wright, Alan F and Witteman, Jacqueline C. M and Wilson, James F and Willemsen, Gonneke and Wichmann, H.-Erich and Whitfield, John B and Waterworth, Dawn M and Wareham, Nicholas J and Waeber, Gérard and Vollenweider, Peter and Voight, Benjamin F and Vitart, Veronique and Uitterlinden, Ane G and Uda, Manuela and Tuomilehto, Jaakko and Thompson, John R and Tanaka, Toshiko and Surakka, Ida and Stringham, Heather M and Spector, Tim D and Soranzo, Nicole and Smit, Johannes H and Sinisalo, Juha and Silander, Kaisa and Sijbrands, Eric J. G and Scuteri, Angelo and Scott, James and Schlessinger, David and Sanna, Serena and Salomaa, Veikko and Saharinen, Juha and Sabatti, Chiara and Ruokonen, Aimo and Rudan, Igor and Rose, Lynda M and Roberts, Robert and Rieder, Mark and Psaty, Bruce M and Pramstaller, Peter P and Pichler, Irene and Perola, Markus and Penninx, Brenda W. J. H and Pedersen, Nancy L and Pattaro, Cristian and Parker, Alex N and Pare, Guillaume and Oostra, Ben A and O'Donnell, Christopher J and Nieminen, Markku S and Nickerson, Deborah A and Montgomery, Grant W and Meitinger, Thomas and McPherson, Ruth and McCarthy, Mark I and ... and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Institutionen för genetik och patologi and Uppsala universitet
Nature, ISSN 0028-0836, 2010, Volume 466, Issue 7307, pp. 707 - 713
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most... 
CHOLESTEROL | MULTIDISCIPLINARY SCIENCES | DISEASE | HUMANS | RISK | TRIGLYCERIDES | TRAITS | GENOME-WIDE ASSOCIATION | Humans | Asian Continental Ancestry Group - genetics | Genetic Loci - genetics | Male | Coronary Artery Disease - blood | Europe - ethnology | Lipids - blood | N-Acetylgalactosaminyltransferases - genetics | Protein Phosphatase 1 - genetics | Cholesterol, LDL - blood | Female | Lipid Metabolism - genetics | N-Acetylgalactosaminyltransferases - metabolism | European Continental Ancestry Group - genetics | Genome-Wide Association Study | Reproducibility of Results | Liver - metabolism | African Americans - genetics | Genotype | Phenotype | Protein Phosphatase 1 - metabolism | Animals | Coronary Artery Disease - therapy | Coronary Artery Disease - genetics | Triglycerides - blood | Cholesterol, HDL - blood | Polymorphism, Single Nucleotide - genetics | Mice | Genetic research | Genetic aspects | Genomes | Blood lipids | Properties | Identification and classification | Women | Plasma | Lipids | Lipoproteins | Genetic engineering | Cholesterol | Medical and Health Sciences | MEDICINE | Medicin och hälsovetenskap | MEDICIN
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17. Full Text A statin-dependent QTL for GATM expression is associated with statin-induced myopathy
by Mangravite, Lara M and Engelhardt, Barbara E and Medina, Marisa W and Smith, Joshua D and Brown, Christopher D and Chasman, Daniel I and Mecham, Brigham H and Howie, Bryan and Shim, Heejung and Naidoo, Devesh and Feng, Qiping and Rieder, Mark J and Chen, Yii.-Der I and Rotter, Jerome I and Ridker, Paul M and Hopewell, Jemma C and Parish, Sarah and Armitage, Jane and Collins, Rory and Wilke, Russell A and Nickerson, Deborah A and Stephens, Matthew and Krauss, Ronald M
Nature, ISSN 0028-0836, 2013, Volume 502, Issue 7471, pp. 377 - 380
Statins are prescribed widely to lower plasma low-density lipoprotein (LDL) concentrations and cardiovascular disease risk(1) and have been shown to have... 
TRANSFORMATION | METAANALYSIS | CHOLESTEROL | LIPID-LOWERING RESPONSE | MULTIDISCIPLINARY SCIENCES | SIMVASTATIN THERAPY | RISK | LOCI | HUMAN GENE-EXPRESSION | PARTICIPANTS | DISCOVERY | Lymphocytes - metabolism | Cell Line | Transcription, Genetic - drug effects | Amidinotransferases - deficiency | Simvastatin - adverse effects | Cholesterol - deficiency | Muscular Diseases - metabolism | Humans | Amidinotransferases - genetics | Lymphocytes - cytology | Sterol Regulatory Element Binding Proteins - metabolism | Cholesterol - metabolism | Simvastatin - pharmacology | Amidinotransferases - metabolism | Gene Knockdown Techniques | Gene Expression Regulation - drug effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - adverse effects | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Lymphocytes - drug effects | Cholesterol - pharmacology | Polymorphism, Single Nucleotide - genetics | Muscular Diseases - chemically induced | Muscular Diseases - genetics | Quantitative Trait Loci - genetics | Quantitative trait loci | Complications and side effects | Medical research | Patient outcomes | Transferases | Physiological aspects | Medicine, Experimental | Research | Statins | Proteins | Plasma | Sterols | Rodents | Homeostasis | Biosynthesis | Kinases | Metabolism | Gene expression | Cholesterol | Methods | Index Medicus
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18. Full Text Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans
: Insulin Sensitivity in Aging
by Ehrhardt, Nicole and Cui, Jinrui and Dagdeviren, Sezin and Saengnipanthkul, Suchaorn and Goodridge, Helen S and Kim, Jason K and Lantier, Louise and Guo, Xiuqing and Chen, Yii-Der I and Raffel, Leslie J and Buchanan, Thomas A and Hsueh, Willa A and Rotter, Jerome I and Goodarzi, Mark O and Péterfy, Miklós
Obesity, ISSN 1930-7381, 03/2019, Volume 27, Issue 3, pp. 434 - 443
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19. Full Text Leptin-Mediated Increases in Catecholamine Signaling Reduce Adipose Tissue Inflammation via Activation of Macrophage HDAC4
by Luan, Bing and Goodarzi, Mark O and Phillips, Naomi G and Guo, Xiuqing and Chen, Yii-Der I and Yao, Jie and Allison, Matthew and Rotter, Jerome I and Shaw, Reuben and Montminy, Marc
Cell Metabolism, ISSN 1550-4131, 06/2014, Volume 19, Issue 6, pp. 1058 - 1065
Obesity promotes systemic insulin resistance through inflammatory changes that lead to the release of cytokines from activated macrophages. Although the... 
ENERGY-BALANCE | TARGETED DISRUPTION | INHIBITION | CRTC3 | KINASE | ENDOCRINOLOGY & METABOLISM | IKK-BETA | CREB COACTIVATOR TORC2 | EXCHANGE | CAMP | INDUCED INSULIN-RESISTANCE | CELL BIOLOGY | Phosphorylation | Histone Deacetylases - biosynthesis | Catecholamines - metabolism | Transcription Factor RelA - antagonists & inhibitors | Obesity - immunology | Humans | Leptin - metabolism | Adipose Tissue - immunology | Lipopolysaccharides - immunology | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cholera Toxin - immunology | Viper Venoms - immunology | Panniculitis - immunology | Cyclic AMP - metabolism | Macrophages - immunology | Histone Deacetylases - genetics | Signal Transduction | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Histone Deacetylases - metabolism | Inflammation | Pertussis Toxin - immunology | Mice, Knockout | Obesity - metabolism | Animals | Energy Metabolism | Transcription Factor RelA - metabolism | Transcription Factor RelA - biosynthesis | Insulin Resistance - immunology | Mice, Obese | Mice | Polymorphism, Single Nucleotide | Adipose tissues | Peptides | Leptin | Catecholamines | Insulin resistance | Macrophages | Gene expression | Phosphotransferases
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