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NeuroReport, ISSN 0959-4965, 07/2017, Volume 28, Issue 10, pp. 590 - 597
(−)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenolic extract in green tea and it has attracted increasing attention for its multiple... 
Journal Article
Nature, ISSN 0028-0836, 07/2016, Volume 535, Issue 7610, pp. 148 - 152
The non-receptor protein tyrosine phosphatase SHP2, encoded by PTPN11, has an important role in signal transduction downstream of growth factor receptor... 
TARGET | POTENT | PTPN11 | PROTOONCOGENE | MULTIDISCIPLINARY SCIENCES | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - metabolism | Humans | Extracellular Signal-Regulated MAP Kinases - metabolism | Oncogene Protein p21(ras) - metabolism | Pyrimidines - chemistry | Piperidines - pharmacology | Inhibitory Concentration 50 | Female | Allosteric Regulation - drug effects | Piperidines - chemistry | Reproducibility of Results | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - antagonists & inhibitors | Models, Molecular | Neoplasms - enzymology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - chemistry | Pyrimidines - pharmacology | Receptor Protein-Tyrosine Kinases - metabolism | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Animals | MAP Kinase Signaling System - drug effects | Mice, Nude | Piperidines - therapeutic use | Pyrimidines - therapeutic use | Protein Stability - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | Protein Tyrosine Phosphatase, Non-Receptor Type 11 - genetics | Neoplasms - pathology | Protein Structure, Tertiary - drug effects | Phosphatases | Observations | Health aspects | Phosphotransferases | Protein-protein interactions | Signal transduction | Cell growth | Peptides | Kinases | Phosphatase | Drug dosages | Cancer | BASIC BIOLOGICAL SCIENCES
Journal Article
NeuroReport, ISSN 0959-4965, 2017, Volume 28, Issue 10, pp. 590 - 597
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 01/2020, Volume 186, p. 111851
Forty-eight analogues of CP-31398, an antitumor agent modulated the mutant gene were synthesized and their cytotoxicities against four cancer cell lines with... 
Synthesis | Anticancer | CP-31398 | DNA intercalator | 2-Styryl-4-aminoquinazoline
Journal Article
Journal Article
Inorganic Chemistry, ISSN 0020-1669, 05/2014, Volume 53, Issue 10, pp. 5029 - 5036
Two enantiotopic 1D chain compounds, [Cu3(L1)3(H2O)2(H2W12O40)]·4H2O (1a,b; L1 = 2-(4,6-bis(pyridin-2-yl)pyridin-2-yl)pyridine), crystallizing in the chiral... 
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 03/2017, Volume 37, Issue 6
Journal Article
Physical Review Letters, ISSN 0031-9007, 04/2016, Volume 116, Issue 15, p. 151803
We construct a weakly coupled renormalizable model to explain the 750 GeV diphoton excess. The 750 GeV resonance [denoted as X(750)] is interpreted as a... 
ANATOMY | HIGGS-BOSON | RESONANCE | PHYSICS, MULTIDISCIPLINARY | SEARCH | ELECTROWEAK SYMMETRY-BREAKING | ROOT-S=8 TEV | MASS | PP COLLISIONS | PHYSICS | MODEL | Phenomenology | Decay rate | Large Hadron Collider | Dark matter | Flavor (particle physics) | Decay | Joining | Mathematical models
Journal Article
Environmental Science and Technology, ISSN 0013-936X, 2019, Volume 53, Issue 7, pp. 3802 - 3810
The increasing use of silver-containing nanoparticles (NPs) in commercial products has led to NP accumulation in the environment and potentially in food webs.... 
DIETARY UPTAKE | BIOACCUMULATION | SEWAGE-SLUDGE | ENVIRONMENTAL SCIENCES | TROPHIC TRANSFER | ENGINEERING, ENVIRONMENTAL | SULFIDE NANOPARTICLES | WASTE-WATER | NANOMATERIALS | ACCUMULATION | LACTUCA-SATIVA | Chemical speciation | Soybeans | Roots | Terrestrial environments | Mollusks | Food webs | Nanoparticles | Leaves | Silver | Organic chemistry | Food chains | Snails | Hydroponics | Stable isotopes | Herbivores
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 09/2016, Volume 59, Issue 17, pp. 7773 - 7782
Journal Article
Cancer letters, ISSN 0304-3835, 01/2020, Volume 473, pp. 74 - 89
Gastrointestinal cancer causes countless deaths every year due to therapeutic resistance. However, whether metabolic alterations contribute to chemoresistance... 
Journal Article
BMC Bioinformatics, ISSN 1471-2105, 12/2019, Volume 20, Issue S22, pp. 1 - 8
Abstract Background Subcellular localization prediction of protein is an important component of bioinformatics, which has great importance for drug design and... 
Position-specific score matrix | Gene ontology | Support vector machine | Physicochemical properties | Principal component analysis
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 05/2019, Volume 169, pp. 144 - 158
Thirty Cryptolepine and Aromathecin based mimics were designed and synthesized. Their cytotoxicity was evaluated in four human cancer cell lines (HepG-2, T24,... 
Aromathecins | Cryptolepine | Topo I inhibitor | G-quadruplex-binding and DNA-Cleavage agent