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Journal Article
2007, AD-a478 473.
The monomeric Ral GTPases, RalA and RalB have been recognized as core components of the regulatory framework supporting tumorigenic transformation.... 
mammary glands | receptor sites(physiology) | proteins | therapy | cells(biology) | oncogenic transformation | breast cancer | apoptosis | tumor growth | survivability | oncogenic viruses
Government Document
Journal of Molecular Medicine, ISSN 0946-2716, 3/2014, Volume 92, Issue 3, pp. 277 - 290
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2018, Volume 61, Issue 21, pp. 9691 - 9721
HIF-2α, a member of the HIF family of transcription factors, is a key oncogenic driver in cancers such as clear cell renal cell carcinoma (ccRCC). A signature... 
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 05/2011, Volume 108, Issue 21, p. 8674
Tumor cells require a constant supply of macromolecular precursors, and interrupting this supply has been proposed as a therapeutic strategy in cancer.... 
Studies | Cell culture | Cell growth | Metabolism | Cells | Tumors
Journal Article
Ras 小G蛋白家族在惡性轉型過程中有很重要的地位, 而其中 RhoA 家族成員對此一過程更有重要影響。轉型細胞的重要特徵是不需依附在其他組織即能生長,而且能避免因脫離細胞間質而產生細胞凋亡 (anoikis)。我們已證明持續性活化的 Cdc42... 
anoikis | 細胞凋亡 | Cdc42
Dissertation