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1. Full Text Experimental study on crack propagation control and mechanism analysis of directional hydraulic fracturing
by Cheng, Yugang and Lu, Yiyu and Ge, Zhaolong and Cheng, Liang and Zheng, Jingwei and Zhang, Wenfeng
Fuel (Guildford), ISSN 0016-2361, 04/2018, Volume 218, pp. 316 - 324
Hydraulic slotting | Permeability enhancement | Hydraulic fracturing | Crack propagation | Coalbed methane | Engineering | Engineering, Chemical | Technology | Energy & Fuels | Science & Technology | Methane | Numerical analysis | Oil wells | Analysis | Mineral industry | Permeability | Mining industry | Fracture mechanics | Computer simulation | Boreholes | Maximum principle | Coefficients | Experiments | Stress | Coal mines | Simulation | Coal | Technology assessment | Rocks | Outbursts | Mathematical models | Stress propagation | Hydraulic pressure | Deviation | Crack initiation
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2. Full Text Mass Spectrometry-Sensitive Probes Coupled with Direct Analysis in Real Time for Simultaneous Sensing of Chemical and Biological Properties of Botanical Drugs
by Li, Zhenhao and Wang, Yi and Cheng, Yiyu
Analytical chemistry (Washington), ISSN 0003-2700, 07/2019, Volume 91, Issue 14, pp. 9001 - 9009
Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Drugs | Chemical tests | Biological properties | Multiplexing | Spectroscopy | Enzymes | Enzyme activity | Control methods | Mass spectroscopy | Pharmacology | Drug development | Real time | Chemical compounds | Biological activity | Substrates | Organic chemistry | Constituents | Enzymatic activity | Piperazine | Quality control | Scientific imaging | Mass spectrometry | Probes | Index Medicus
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3. Full Text Drug–Disease Association and Drug-Repositioning Predictions in Complex Diseases Using Causal Inference–Probabilistic Matrix Factorization
by Yang, Jihong and Li, Zheng and Fan, Xiaohui and Cheng, Yiyu
Journal of chemical information and modeling, ISSN 1549-9596, 09/2014, Volume 54, Issue 9, pp. 2562 - 2569
Computer Science, Information Systems | Physical Sciences | Computer Science, Interdisciplinary Applications | Chemistry | Life Sciences & Biomedicine | Technology | Computer Science | Pharmacology & Pharmacy | Chemistry, Medicinal | Chemistry, Multidisciplinary | Science & Technology | Models, Theoretical | Probability | Disease | Causality | Humans | Drug Therapy | Cardiovascular disease | Breast cancer | Diabetes | Medical treatment | Tumors | Index Medicus
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4. Full Text Rapid screening and identification of α‐glucosidase inhibitors from mulberry leaves using enzyme‐immobilized magnetic beads coupled with HPLC/MS and NMR
by Tao, Yi and Zhang, Yufeng and Cheng, Yiyu and Wang, Yi
Biomedical chromatography, ISSN 0269-3879, 02/2013, Volume 27, Issue 2, pp. 148 - 155
Morus alba | α‐glucosidase inhibitor | magnetic beads | α-glucosidase inhibitor | Magnetic beads | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Pharmacology & Pharmacy | Chemistry, Analytical | Science & Technology | Enzymes, Immobilized - metabolism | Glycoside Hydrolase Inhibitors | Plant Extracts - chemistry | Chromatography, High Pressure Liquid - methods | Plant Extracts - pharmacology | Magnets | Quercetin - isolation & purification | Enzyme Inhibitors - chemistry | Kaempferols - isolation & purification | Kaempferols - analysis | Methanol - chemistry | Plant Leaves - chemistry | Quercetin - analogs & derivatives | Quercetin - chemistry | Kaempferols - chemistry | Quercetin - analysis | Enzyme Inhibitors - pharmacology | Enzyme Inhibitors - analysis | Drug Discovery | Enzyme Inhibitors - isolation & purification | Quercetin - pharmacology | Nuclear Magnetic Resonance, Biomolecular - methods | Magnetics - methods | Enzymes, Immobilized - antagonists & inhibitors | Kaempferols - pharmacology | Mass Spectrometry - methods | alpha-Glucosidases - metabolism | Morus - chemistry | Index Medicus
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5. Full Text On the Efficacy of Through-Silicon-Via Inductors
by Tida, Umamaheswara Rao and Rongbo Yang and Cheng Zhuo and Yiyu Shi
IEEE transactions on very large scale integration (VLSI) systems, ISSN 1063-8210, 07/2015, Volume 23, Issue 7, pp. 1322 - 1334
Q-factor | Inductance | microchannel | Spirals | Metals | Three-dimensional integrated circuit (3-D IC) | Inductors | Through-silicon vias | Substrates | through-silicon-via (TSV) inductors | Engineering, Electrical & Electronic | Engineering | Computer Science, Hardware & Architecture | Technology | Computer Science | Science & Technology
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6. Full Text A Raman spectroscopy analysis method for rapidly determining saccharides and its application to monitoring the extraction process of Wenxin granule manufacturing procedure
by Jin, Lei and Wang, Shufang and Cheng, Yiyu
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, ISSN 1386-1425, 11/2020, Volume 241, p. 118603
Process monitoring | Raman spectroscopy | Competitive adaptive reweighted sampling | Partial least squares | Saccharides | Spectroscopy | Technology | Science & Technology
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7. Full Text MiR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR-p-PI3K/AKT-c-JUN
by Zhao, Mengyang and Luo, Rongcheng and Liu, Yiyi and Gao, Linyuan and Fu, Zhaojian and Fu, Qiaofen and Luo, Xiaojun and Chen, Yiyu and Deng, Xiaojie and Liang, Zixi and Li, Xin and Cheng, Chao and Liu, Zhen and Fang, Weiyi
Nature communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, pp. 11309 - 11309
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Nasopharyngeal Neoplasms - genetics | Neoplasm Transplantation | Nasopharyngeal Neoplasms - metabolism | Carcinoma | Prognosis | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | JNK Mitogen-Activated Protein Kinases - metabolism | Male | MicroRNAs - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Proto-Oncogene Proteins c-akt - genetics | Nasopharyngeal Neoplasms - pathology | TOR Serine-Threonine Kinases - genetics | Cell Transformation, Neoplastic - genetics | Forkhead Transcription Factors - metabolism | Aged, 80 and over | Adult | Female | JNK Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Nasopharyngeal Neoplasms - diagnosis | Nasopharyngeal Carcinoma | Signal Transduction | Forkhead Transcription Factors - genetics | Cell Transformation, Neoplastic - metabolism | Phosphatidylinositol 3-Kinases - genetics | Drug Resistance, Neoplasm - genetics | Feedback, Physiological | Animals | Survival Analysis | Cell Line, Tumor | Aged | Forkhead Box Protein O1 | Mice | MicroRNAs - genetics | Cell Transformation, Neoplastic - pathology | Neoplasm Staging | Index Medicus
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8. Full Text Specific turn-on fluorescent probe with aggregation-induced emission characteristics for SIRT1 modulator screening and living-cell imaging
by Wang, Yi and Chen, Yaqi and Wang, Haibo and Cheng, Yiyu and Zhao, Xiaoping
Analytical chemistry (Washington), ISSN 0003-2700, 05/2015, Volume 87, Issue 10, pp. 5046 - 5049
Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Sirtuin 1 - metabolism | Cell Line | Fluorescent Dyes - chemistry | Myocytes, Cardiac - cytology | Cell Survival | Humans | Enzyme Inhibitors - pharmacology | Rats | Molecular Imaging - methods | Enzyme Activation - drug effects | Sirtuin 1 - antagonists & inhibitors | Animals | Acetylation | Probes (Electronic instruments) | Usage | Research | Chemical synthesis | Proteins | Cardiomyocytes | Peptides | Metabolic disorders | Stem cells | Index Medicus | Screening | Inhibitors | Modulation | Disorders | Emission | Monitors | Nicotinamide adenine dinucleotide | Modulators
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9. Strategies and Techniques for Multi-Component Drug Design from Medicinal Herbs and Traditional Chinese Medicine
by Wang, Yi and Fan, Xiaohui and Qu, Haibin and Gao, Xiumei and Cheng, Yiyu
Current topics in medicinal chemistry, ISSN 1568-0266, 06/2012, Volume 12, Issue 12, pp. 1356 - 1362
Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | High-Throughput Nucleotide Sequencing | Animals | Medicine, Chinese Traditional | Humans | Plants, Medicinal | Drug Design
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10. Full Text Targeting the differential addiction to anti-apoptotic BCL-2 family for cancer therapy
by Inoue-Yamauchi, Akane and Jeng, Paul S and Kim, Kwanghee and Chen, Hui-Chen and Han, Song and Ganesan, Yogesh Tengarai and Ishizawa, Kota and Jebiwott, Sylvia and Dong, Yiyu and Pietanza, Maria C and Hellmann, Matthew D and Kris, Mark G and Hsieh, James J and Cheng, Emily H
Nature communications, ISSN 2041-1723, 07/2017, Volume 8, Issue 1, pp. 16078 - 16078
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Lung Neoplasms - drug therapy | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Drug Resistance, Neoplasm | Molecular Targeted Therapy | Apoptosis Regulatory Proteins - drug effects | Myeloid Cell Leukemia Sequence 1 Protein - drug effects | Small Cell Lung Carcinoma - drug therapy | Small Cell Lung Carcinoma - metabolism | bcl-X Protein - drug effects | Proto-Oncogene Proteins c-bcl-2 - metabolism | bcl-X Protein - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Myeloid Cell Leukemia Sequence 1 Protein - antagonists & inhibitors | Aniline Compounds - pharmacology | Cyclin-Dependent Kinase 9 - antagonists & inhibitors | Sulfonamides - pharmacology | Apoptosis Regulatory Proteins - metabolism | Drug Synergism | Pyridinium Compounds - pharmacology | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | High-Throughput Screening Assays | Apoptosis Regulatory Proteins - antagonists & inhibitors | Proto-Oncogene Proteins c-bcl-2 - drug effects | Cell Line, Tumor | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | bcl-X Protein - metabolism | Doxorubicin - pharmacology | Regulators | Bax protein | Bcl-2 protein | Small cell lung carcinoma | Lung cancer | High-throughput screening | Doxorubicin | BAK protein | Mcl-1 protein | Proteins | Mitochondria | Inhibitors | Bcl-x protein | Anthracycline | Addiction | Cell death | Sequestering | Cancer | Apoptosis | Index Medicus
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11. Full Text Single-Inductor-Multiple-Tier Regulation: TSV-Inductor-Based On-Chip Buck Converters for 3-D IC Power Delivery
by Tida, Umamaheswara Rao and Zhuo, Cheng and Shi, Yiyu
IEEE transactions on very large scale integration (VLSI) systems, ISSN 1063-8210, 10/2019, Volume 27, Issue 10, pp. 2305 - 2316
Buck converters | Metals | System-on-chip | Inductors | Through-silicon vias | Voltage control | On-chip regulators | power delivery for 3-D integrated circuits (3-D ICs) | through-silicon-via inductor (TSV-Inductor) | Engineering, Electrical & Electronic | Engineering | Computer Science, Hardware & Architecture | Technology | Computer Science | Science & Technology
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12. Full Text An ultrafiltration high-performance liquid chromatography coupled with diode array detector and mass spectrometry approach for screening and characterising tyrosinase inhibitors from mulberry leaves
by Yang, Zhenzhong and Zhang, Yufeng and Sun, Lijuan and Wang, Yi and Gao, Xiumei and Cheng, Yiyu
Analytica chimica acta, ISSN 0003-2670, 03/2012, Volume 719, pp. 87 - 95
Ultrafiltration | Tyrosinase inhibitor | Morus alba | HPLC–DAD–MS | HPLC-DAD-MS | Physical Sciences | Chemistry | Chemistry, Analytical | Science & Technology | Analytical chemistry | Chromatographic methods and physical methods associated with chromatography | Other chromatographic methods | Exact sciences and technology | Spectrometric and optical methods | Mass Spectrometry - economics | Plant Leaves - chemistry | Chromatography, High Pressure Liquid - methods | Drug Discovery - economics | Enzyme Inhibitors - pharmacology | Monophenol Monooxygenase - antagonists & inhibitors | Enzyme Inhibitors - isolation & purification | Monophenol Monooxygenase - metabolism | Enzyme Inhibitors - chemistry | Protein Binding | Chromatography, High Pressure Liquid - economics | Agaricales - enzymology | Binding Sites | Mass Spectrometry - methods | Morus - chemistry | Circuit components | Medicine, Chinese | Liquid chromatography | Medical screening | Mass spectrometry | Detectors | Binding | Screening | Inhibitors | Arrays | Diodes | Tyrosinase | Index Medicus
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