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Scientific Reports, ISSN 2045-2322, 04/2016, Volume 6, Issue 1, pp. 24570 - 24570
Characterizing the behavior of disease genes in the context of biological networks has the potential to shed light on disease mechanisms, and to reveal both... 
DATABASE | SCALE MAP | MULTIDISCIPLINARY SCIENCES | GENES | FRAMEWORK | DISORDERS | TOPOLOGICAL FEATURES | INHERITANCE | PROTEIN-INTERACTION NETWORK | CANCER | INTERACTOME | Computational Biology - methods | High-Throughput Nucleotide Sequencing | Neoplasms - genetics | Humans | Abundance | Heredity | Gene loci | Disease | Cancer | Index Medicus | Genomes | Anàlisi | Biologia
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 01/2016, Volume 10, Issue 1
  Drug development for neglected diseases has been historically hampered due to lack of market incentives. The advent of public domain resources containing... 
Drugs | Proteins | Pathogens | E coli | Research & development--R&D | Organisms | Pharmaceutical industry | Experiments | Cost control | Tropical diseases | Biological activity
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2013, Volume 110, Issue 29, pp. 12120 - 12125
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2014, Volume 111, Issue 42, pp. 15166 - 15171
Growing evidence suggests that core spliceosomal components differentially affect RNA processing of specific genes; however, whether changes in the levels or... 
Alternative splicing | Phenotypes | Messenger RNA | Splicing | Introns | Genes | Gene expression regulation | Circadian rhythm | Down regulation | Genetic mutation | Circadian clock | Mammals | Posttranscriptional | Arabidopsis | posttranscriptional | RNA INTERFERENCE | ANALYSIS REVEALS | SEQ ANALYSIS | CLOCK GENE | alternative splicing | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | SPLICEOSOME | IDENTIFICATION | circadian clock | DROSOPHILA | mammals | SM-LIKE PROTEIN | RNA-Binding Proteins - genetics | Alternative Splicing | Genomics | Humans | Ribonucleoproteins, Small Nuclear - genetics | Spliceosomes - metabolism | Gene Expression Regulation, Plant | Suprachiasmatic Nucleus - metabolism | Plant Proteins - metabolism | Arabidopsis Proteins - genetics | Arabidopsis Proteins - physiology | RNA-Binding Proteins - physiology | Signal Transduction | Mice, Transgenic | Circadian Rhythm | Arabidopsis - metabolism | Phenotype | Animals | Sequence Analysis, RNA | Plant Leaves - metabolism | Ribonucleoproteins, Small Nuclear - physiology | Alleles | Cell Line, Tumor | Mice | Mutation | RNA, Small Interfering - metabolism | Circadian rhythms | Genetic research | Genetic aspects | Research | RNA processing | Genetic regulation | Signal transduction | Rodents | Flowers & plants | Ribonucleic acid--RNA | Gene expression | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2015, Volume 112, Issue 30, pp. 9382 - 9387
Journal Article
Nucleic acids research, ISSN 0305-1048, 2013, Volume 41, Issue W1, pp. W8 - 14
Journal Article
PLoS Genetics, ISSN 1553-7390, 02/2015, Volume 11, Issue 2
  Wound healing is an essential homeostatic mechanism that maintains the epithelial barrier integrity after tissue damage. Although we know the overall steps... 
Studies | Wound healing | Insects | Microscopy | Laboratories | Mammals | Gene expression | Experiments
Journal Article
by Menden, Michael P and Wang, Dennis and Mason, Mike J and Szalai, Bence and Bulusu, Krishna C and Guan, Yuanfang and Yu, Thomas and Kang, Jaewoo and Jeon, Minji and Wolfinger, Russ and Nguyen, Tin and Zaslavskiy, Mikhail and Abante, Jordi and Abecassis, Barbara Schmitz and Aben, Nanne and Aghamirzaie, Delasa and Aittokallio, Tero and Akhtari, Farida S and Al-lazikani, Bissan and Alam, Tanvir and Allam, Amin and Allen, Chad and de Almeida, Mariana Pelicano and Altarawy, Doaa and Alves, Vinicius and Amadoz, Alicia and Anchang, Benedict and Antolin, Albert A and Ash, Jeremy R and Aznar, Victoria Romeo and Ba-alawi, Wail and Bagheri, Moeen and Bajic, Vladimir and Ball, Gordon and Ballester, Pedro J and Baptista, Delora and Bare, Christopher and Bateson, Mathilde and Bender, Andreas and Bertrand, Denis and Wijayawardena, Bhagya and Boroevich, Keith A and Bosdriesz, Evert and Bougouffa, Salim and Bounova, Gergana and Brouwer, Thomas and Bryant, Barbara and Calaza, Manuel and Calderone, Alberto and Calza, Stefano and Capuzzi, Stephen and Carbonell-Caballero, Jose and Carlin, Daniel and Carter, Hannah and Castagnoli, Luisa and Celebi, Remzi and Cesareni, Gianni and Chang, Hyeokyoon and Chen, Guocai and Chen, Haoran and Chen, Huiyuan and Cheng, Lijun and Chernomoretz, Ariel and Chicco, Davide and Cho, Kwang-Hyun and Cho, Sunghwan and Choi, Daeseon and Choi, Jaejoon and Choi, Kwanghun and Choi, Minsoo and Cock, Martine De and Coker, Elizabeth and Cortes-Ciriano, Isidro and Cserzö, Miklós and Cubuk, Cankut and Curtis, Christina and Daele, Dries Van and Dang, Cuong C and Dijkstra, Tjeerd and Dopazo, Joaquin and Draghici, Sorin and Drosou, Anastasios and Dumontier, Michel and Ehrhart, Friederike and Eid, Fatma-Elzahraa and ElHefnawi, Mahmoud and Elmarakeby, Haitham and van Engelen, Bo and Engin, Hatice Billur and de Esch, Iwan and Evelo, Chris and Falcao, Andre O and Farag, Sherif and Fernandez-Lozano, Carlos and Fisch, Kathleen and Flobak, Asmund and Fornari, Chiara and Foroushani, Amir B. K and Fotso, Donatien Chedom and Fourches, Denis and ... and AstraZeneca-Sanger Drug Combinatio and AstraZeneca-Sanger Drug Combination DREAM Consortium
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 2674 - 17
The effectiveness of most cancer targeted therapies is short-lived. Tumors often develop resistance that might be overcome with drug combinations. However, the... 
BREAST-CANCER | ANDROGEN RECEPTOR | INHIBITION | GENE | PATHWAY | LANDSCAPE | MULTIDISCIPLINARY SCIENCES | RESISTANCE | MUTATIONS | CELL | RESOURCE | Identification methods | Pharmacology | Tumor cell lines | 1-Phosphatidylinositol 3-kinase | Antagonism | Computation | Cell lines | Computer applications | Predictions | Biomarkers | Bioindicators | Cancer | Tumors | Index Medicus
Journal Article