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Scientific Reports, ISSN 2045-2322, 12/2018, Volume 8, Issue 1, pp. 12519 - 14
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2018, Volume 128, Issue 6, pp. 2325 - 2338
ONC201 is a first-in-class, orally active antitumor agent that upregulates cytotoxic TRAIL pathway signaling in cancer cells. ONC201 has demonstrated safety... 
MEDICINE, RESEARCH & EXPERIMENTAL | APOPTOSIS | NATURAL-KILLER-CELLS | EFFECTOR FUNCTIONS | TUMOR-METASTASIS | ANTICANCER AGENT | SMALL-MOLECULE ONC201/TIC10 | LIGAND | INTEGRATED STRESS-RESPONSE | CANCER | CD8(+) T-CELLS | Cell Survival - drug effects | HCT116 Cells | Humans | Cell Death - immunology | Killer Cells, Natural - pathology | TNF-Related Apoptosis-Inducing Ligand - immunology | Cell Survival - immunology | Heterocyclic Compounds, 4 or More Rings - pharmacology | Dose-Response Relationship, Drug | Xenograft Model Antitumor Assays | Signal Transduction - immunology | Neoplasm Metastasis | Animals | Colorectal Neoplasms - immunology | Signal Transduction - drug effects | Mice, Nude | Colorectal Neoplasms - drug therapy | Killer Cells, Natural - immunology | Female | Cell Proliferation - drug effects | Mice | Cell Death - drug effects | Colorectal Neoplasms - pathology | Antimitotic agents | Killer cells | Care and treatment | Ligands (Biochemistry) | Physiological aspects | Dosage and administration | Metastasis | Antineoplastic agents | Drug therapy | Health aspects | Methods | Cancer | Bax protein | PD-1 protein | Clinical trials | Cytotoxicity | T cell receptors | CD3 antigen | Patients | Metastases | Signal transduction | Cell death | Peripheral blood | Degranulation | Antitumor activity | Tumor necrosis factor-TNF | Natural killer cells | Cell migration | Apoptosis
Journal Article
Journal Article
Journal Article
FASEB Journal, ISSN 1530-6860, 06/2016, Volume 30, Issue 6, p. 86
Recent data shows that fibroblast growth factor 14 (FGF14) binds to and controls the function of the voltage-gated sodium (Nav) channel with phenotypic... 
Journal Article
Journal Article
Journal of Materials Chemistry B, ISSN 2050-7518, 2016, Volume 4, Issue 9, pp. 1640 - 1649
To combat mucosal pathogens that cause gastrointestinal (GI) infections, local mucosal immunity is required which is best achieved through oral vaccination.... 
SYSTEM | MUCOSA | CELLS | DESIGN | MATERIALS SCIENCE, BIOMATERIALS | POLYMERIC NANOPARTICLES | INNATE | ANTIBODY-RESPONSES | ADAPTIVE IMMUNE-RESPONSES | ANTIGEN DELIVERY
Journal Article
ISSN 2050-750X, 2/2016, Volume 4, Issue 9, pp. 164 - 1649
To combat mucosal pathogens that cause gastrointestinal (GI) infections, local mucosal immunity is required which is best achieved through oral vaccination.... 
Journal Article
Journal of materials chemistry. B, Materials for biology and medicine, ISSN 2050-750X, 02/2016, Volume 4, Issue 9, pp. 1640 - 1649
To combat mucosal pathogens that cause gastrointestinal (GI) infections, local mucosal immunity is required which is best achieved through oral vaccination.... 
Drug delivery systems | Peptides | Barriers | Calcium carbonate | Mucus | Nanostructure | Vaccines | Microparticles
Journal Article
ACS Biomaterials Science & Engineering, ISSN 2373-9878, 02/2017, Volume 3, Issue 2, pp. 126 - 143
Natural and synthetic biomaterials are increasingly being used for the development of vaccines and immuno­therapies as alternatives to traditional... 
polymer | vaccine | biomaterial | CD8 | T cell | cellular immunity | MATERIALS SCIENCE, BIOMATERIALS | DENDRITIC CELLS | CATIONIC LIPOSOMES | CD8(+)T cell | CHITOSAN-BASED HYDROGELS | NANOPARTICLE VACCINES | MUCOSAL IMMUNE-RESPONSES | IN-VIVO | ANTIGEN-PRESENTING CELLS | BIOMEDICAL APPLICATIONS | SELF-ASSEMBLING PEPTIDE | T-LYMPHOCYTE RESPONSES
Journal Article
ACS Biomaterials Science & Engineering, ISSN 2373-9878, 07/2015, Volume 1, Issue 7, pp. 601 - 609
d-Amino acid analogs of peptides and proteins are attractive for applications in biotechnology and medicine due to their reduced proteolytic sensitivity. Here,... 
enantiomer | stereochemistry | self-assembly | peptide | adjuvant | nanofiber | D-AMINO ACIDS | SELF-ASSEMBLING PEPTIDES | MATERIALS SCIENCE, BIOMATERIALS | CELL RESPONSES | DENDRITIC CELLS | VACCINE | IMMUNOMODULATION | NALP3 INFLAMMASOME | BETA | IMMUNE-RESPONSES
Journal Article