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Annual Review of Pharmacology and Toxicology, ISSN 0362-1642, 2012, Volume 52, pp. 57 - 78
Journal Article
Journal of Organic Chemistry, ISSN 0022-3263, 08/2004, Volume 69, Issue 17, pp. 5712 - 5719
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 07/2015, Volume 11, Issue 7, pp. 511 - 517
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 10/2002, Volume 124, Issue 39, pp. 11584 - 11585
The first total synthesis of the antiinflammatory marine sponge metabolite (+)-cacospongionolide B has been accomplished in 12 linear steps. The pivotal... 
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 10/2002, Volume 124, Issue 39, pp. 11584 - 11585
Journal Article
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 03/2007, Volume 72, Issue 5, pp. 1545 - 1552
A new approach to (+)-cacospongionolide was developed to access conformationally restricted variants of the natural product. The flexible aliphatic region... 
REARRANGEMENT | ENZYMES | (-)-CACOSPONGIONOLIDE-B | CHEMISTRY, ORGANIC | ALDEHYDES | EXTENSION | ALKYNES | TPAP | Chemical bonds | Phospholipases | Chemical properties | Analysis | Conformational analysis
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2018, Volume 61, Issue 24, pp. 11021 - 11036
Spinal muscular atrophy (SMA), a rare neuromuscular disorder, is the leading genetic cause of death in infants and toddlers. SMA is caused by the deletion or a... 
CHEMISTRY, MEDICINAL | MODIFIERS | IDENTIFICATION | SINGLE NUCLEOTIDE
Journal Article
Journal Article
IDrugs : the investigational drugs journal, 12/2010, Volume 13, Issue 12, p. 862
The application of chemical proteomics to new target discovery can lead to a rapid understanding of disease mechanism and new therapeutic methods. Successful... 
Drug Evaluation, Preclinical - methods | Animals | Signal Transduction - drug effects | Drug Industry - methods | Pharmacology - methods | Humans | Structure-Activity Relationship | Proteomics - methods | Molecular Targeted Therapy | Drug Discovery
Journal Article
IDrugs, ISSN 1369-7056, 12/2010, Volume 13, Issue 12, pp. 862 - 868
The application of chemical proteomics to new target discovery can lead to a rapid understanding of disease mechanism and new therapeutic methods. Successful... 
Affinity chromatography | chemical genetics | cell-based assay | target identification | signaling pathway | chemical proteomics | drug target | PHARMACOLOGY & PHARMACY
Journal Article
Chemistry & Biology, ISSN 1074-5521, 07/2013, Volume 20, Issue 7, pp. 912 - 921
Journal Article
JOURNAL OF ORGANIC CHEMISTRY, ISSN 0022-3263, 08/2004, Volume 69, Issue 17, pp. 5712 - 5719
The total syntheses of the antiinflammatory marine sponge metabolites (+)-cacospongionolide B and E are described. The pivotal steps in the synthetic route... 
ENOL ETHERS | ALPHA,BETA-UNSATURATED KETONES | ABSOLUTE-CONFIGURATION | SPONGE FASCIOSPONGIA-CAVERNOSA | STEREOSELECTIVE CONSTRUCTION | CHEMISTRY, ORGANIC | CELLULAR INTERACTIONS | ENANTIOSELECTIVE TOTAL-SYNTHESIS | ASYMMETRIC ALLYLATION | CATALYZED ENYNE METATHESIS | MARINE NATURAL-PRODUCTS | Phosphorus | Research | Chemical properties
Journal Article
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