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research (2) 2
telomeres (2) 2
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1. Full Text Senescent mesenchymal cells accumulate in human fibrosis by a telomere‐independent mechanism and ameliorate fibrosis through matrix metalloproteinases
by Pitiyage, Gayani Nadika and Slijepcevic, Predrag and Gabrani, Aliya and Chianea, Yaghoub Gozaly and Lim, Kue Peng and Prime, Stephen Stewart and Tilakaratne, Wanninayake Mudiyanselage and Fortune, Farida and Parkinson, Eric Kenneth
The Journal of Pathology, ISSN 0022-3417, 04/2011, Volume 223, Issue 5, pp. 604 - 617
Fibrosis can occur in many organs, where it is a debilitating and preneoplastic condition. The senescence of activated fibroblasts has been proposed to... 
senescence | fibroblast | antioxidants | mitochondria | telomere | reactive oxygen species | fibrosis | Antioxidants | Mitochondria | Reactive oxygen species | Senescence | Fibrosis | Fibroblast | Telomere | LYSYL OXIDASE | DNA-DAMAGE | CYCLE ARREST | AGING MICE | PATHOLOGY | ARECA NUT EXTRACT | CELLULAR SENESCENCE | CANCER | FIBROBLASTS | ORAL SUBMUCOUS FIBROSIS | IN-VITRO | ONCOLOGY | Cell Proliferation | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Oxidative Stress - physiology | Oral Submucous Fibrosis - pathology | Young Adult | Oral Submucous Fibrosis - genetics | Adult | Telomere - physiology | Mesenchymal Stromal Cells - physiology | Fibroblasts - metabolism | Cellular Senescence - genetics | Matrix Metalloproteinase 2 - metabolism | Cells, Cultured | Cellular Senescence - physiology | Mesenchymal Stromal Cells - metabolism | Fibroblasts - pathology | Disease Progression | Oral Submucous Fibrosis - metabolism | Adolescent | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Matrix Metalloproteinases - physiology | Aged | DNA Damage | Mesenchymal Stromal Cells - pathology | Matrix Metalloproteinase 1 - metabolism | Mitochondria - physiology | Drugs | Cell culture | Flow cytometry | Mesenchyme | DNA damage | INK4a protein | Wounds | Matrix metalloproteinase | Panning | Fibronectin | Telomeres | Absorbance | Tobacco | Life span | Biopsy | Chromium | Fibroblasts | Interstitial collagenase | p16 protein | Immune system
Journal Article
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2. Full Text Analysis of telomere length and function in radiosensitive mouse and human cells in response to DNA-PKcs inhibition
by Yasaei, Hemad and Gozaly-Chianea, Yaghoub and Slijepcevic, Predrag
Genome Integrity, ISSN 2041-9414, 03/2013, Volume 4, Issue 1, p. 2
Telomeres, the physical ends of chromosomes, play an important role in preserving genomic integrity. This protection is supported by telomere binding proteins... 
Mouse lymphoma | Telomere dysfunction | DNA-PKcs | Flow-FISH | Radiosensitivity | IC86621 | Artemis | Telomere length
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3. Full Text Investigation of telomere maintenance in BRCA2 defective mammalian cell lines
by Gozaly Chianea, Yaghoub
2014
BRCA2 is a highly penetrant breast cancer predisposing gene. The protein product of the BRCA2 gene mediates repair of breaks in DNA, through Homologous... 
BRCA2 and ALT cell line | ALT and T-SCE | siRNA and BRCA2 | BRCA2 and DNA damage | DNA damage and hamster cell line
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4. Full Text Effects of BRCA2 deficiency on telomere recombination in non-ALT and ALT cells
by Sapir, Ester and Gozaly-Chianea, Yaghoub and Al-Wahiby, Suliman and Ravindran, Sainu and Yasaei, Hemad and Slijepcevic, Predrag
Genome Integrity, ISSN 2041-9414, 12/2011, Volume 2, Issue 1, pp. 9 - 9
Recent studies suggest that BRCA2 affects telomere maintenance. Interestingly, anti cancer treatments that involve BRCA2 and telomerase individually are... 
Physiological aspects | Telomeres | Research | Binding proteins
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