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Angewandte Chemie International Edition, ISSN 1433-7851, 09/2012, Volume 51, Issue 36, pp. 9169 - 9172
Journal Article
Journal Article
Organic Letters, ISSN 1523-7060, 04/2016, Volume 18, Issue 7, pp. 1670 - 1673
A gold-catalyzed cyclization of 1-propargyl-1,2,3,4-tetrahydro-β-carboline led to formation the D-ring of strictamine. Functional group modifications of the... 
REARRANGEMENT | ECHITAMINE | AKUAMMILINE ALKALOIDS | PICRININE | CONSTRUCTION | CHEMISTRY, ORGANIC | STRICTAMINE | CASCADE CYCLIZATION | INDOLE ALKALOIDS | ALSTONIA-SCHOLARIS | HYDROARYLATION | Gold - chemistry | Cyclization | Stereoisomerism | Alkaloids - chemical synthesis | Molecular Structure | Catalysis | Alkaloids - chemistry
Journal Article
Chemical and Pharmaceutical Bulletin, ISSN 0009-2363, 2016, Volume 64, Issue 7, pp. 996 - 1003
A series of novel 3,4,7-trisubstituted benzofuran derivatives were synthesized, and their binding affinity to κ- (KOR) and μ-opioid receptors (MOR) were... 
Journal Article
Journal Article
Nature, ISSN 0028-0836, 08/2009, Volume 460, Issue 7257, pp. 904 - 908
Acquired uniparental disomy(aUPD) is a common feature of cancer genomes, leading to loss of heterozygosity. aUPD is associated not only with loss-of-function... 
TRANSFORMATION | PROTEIN | RETROVIRAL VECTOR GCDNSAP | NEGATIVE REGULATION | MULTIDISCIPLINARY SCIENCES | HEMATOPOIETIC STEM-CELLS | V-CBL | MUTATIONS | UBIQUITIN LIGASES | MYELODYSPLASTIC SYNDROMES | P53 | NIH 3T3 Cells | Neoplasm Transplantation | ras Proteins - genetics | Phosphorylation | Proto-Oncogene Proteins c-cbl - metabolism | Humans | Leukemia, Myeloid - genetics | Molecular Sequence Data | ras Proteins - metabolism | Male | Leukemia, Myeloid - pathology | Allelic Imbalance | Ubiquitination | Base Sequence | Female | Proto-Oncogene Proteins c-cbl - deficiency | Genes, Tumor Suppressor | Proto-Oncogene Proteins c-cbl - genetics | Amino Acid Sequence | Oncogenes - genetics | Mutant Proteins - genetics | Models, Molecular | Mutant Proteins - metabolism | Chromosomes, Human, Pair 11 - genetics | Proto-Oncogene Proteins c-cbl - chemistry | Mice, Knockout | Animals | Uniparental Disomy - genetics | Leukemia, Myeloid - metabolism | Mice, Nude | Mutant Proteins - chemistry | Proto-Oncogene Proteins c-cbl - antagonists & inhibitors | Protein Conformation | Mice | Mutation | Gene mutations | Myelocytic leukemia | Physiological aspects | Tumor suppressor genes | Development and progression | Genetic aspects | Nonlymphoid leukemia | Research | Protein kinases | Proteins | Genes | Amino acids | Kinases | Cells | Clinical outcomes | Crystal structure
Journal Article
Journal Article
Advanced Engineering Materials, ISSN 1438-1656, 02/2019, Volume 21, Issue 2
Journal Article
PLoS Genetics, ISSN 1553-7390, 12/2014, Volume 10, Issue 12
  DNA methylation is globally reprogrammed during mammalian preimplantation development, which is critical for normal development. Recent reduced... 
Studies | Satellites | Biomedical research | Placenta | Sperm | Genes | DNA methylation | Epigenetics | Genomes | Mammals | Blood | Deoxyribonucleic acid--DNA
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 10/1999, Volume 274, Issue 43, pp. 30353 - 30356
Recent investigations have elucidated the cytokine-induced NF-kappa B activation pathway. I kappa B kinase (IKK) phosphorylates inhibitors of NF-kappa B (I... 
SIGNAL | UBIQUITINATION | TUMOR-NECROSIS-FACTOR | ACTIVATION | COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | ALPHA | DEGRADATION | BETA | EPSILON | NF-B protein | IB protein | tumor necrosis factor-a | IKK protein
Journal Article
The Journal of Biochemistry, ISSN 0021-924X, 04/2019, Volume 165, Issue 4, pp. 323 - 334
Abstract Metabolites are sensitive indicators of moment-to-moment cellular status and activity. Expecting that tissue-specific metabolic signatures unveil a... 
metabolism | sperm motility | lactate dehydrogenase A (LDHA) | lactate dehydrogenase C (LDHC) | 2-hydroxyglutarate (2-HG) | ACID | BIOCHEMISTRY & MOLECULAR BIOLOGY | ALPHA-KETOGLUTARATE | MASS-SPECTROMETRY | BACH2 | B-CELLS | ISOZYME | GENE | ONCOMETABOLITE 2-HYDROXYGLUTARATE
Journal Article