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Immunity, ISSN 1074-7613, 03/2012, Volume 36, Issue 3, pp. 401 - 414
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e21477
Chlamydia pneumoniae (CP) is an important human pathogen that causes atypical pneumonia and is associated with various chronic inflammatory disorders.... 
APOPTOSIS | INTERLEUKIN-1 | ACTIVATION | MICE DEFICIENT | IFN-GAMMA | IMMUNE-RESPONSES | MULTIDISCIPLINARY SCIENCES | INNATE | INDUCTION | BLOOD MONONUCLEAR-CELLS | NALP3 INFLAMMASOME | Lung - microbiology | Protein Biosynthesis | Chlamydia Infections - enzymology | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Caspase 1 - metabolism | Chlamydia Infections - immunology | Disease Models, Animal | Interleukin-1beta - secretion | Lung - pathology | Macrophages, Alveolar - microbiology | Pneumonia, Bacterial - complications | Pneumonia, Bacterial - enzymology | Chlamydia Infections - complications | Mitochondria - metabolism | Toll-Like Receptor 2 - metabolism | Immunity, Innate | Macrophages, Alveolar - enzymology | Animals | Carrier Proteins - metabolism | Caspase 1 - deficiency | Survival Analysis | Pneumonia, Bacterial - immunology | Mice | Myeloid Differentiation Factor 88 - metabolism | Lung - immunology | Phagocytosis | Chlamydophila pneumoniae - immunology | Nitric Oxide Synthase Type II - metabolism | Pediatrics | Oxidative stress | Pneumonia | Sexually transmitted diseases--STD | Immune clearance | Infections | Activation | Interleukin 1 receptors | Macrophages | Experiments | Caspase-1 | Mitochondria | Immunology | Chlamydia | Rodents | Interleukin 1 | Toll-like receptors | Bacteria | Alveoli | Immune system | Recombinant | Enzymes | Cytokines | Secretion | Mortality | Caspase | Protein biosynthesis | Pharmacology | Nitric-oxide synthase | Medicine | Signaling | Infectious diseases | Lungs | Protein synthesis | TLR2 protein | MyD88 protein | Potassium | Apoptosis | Reactive oxygen species | Sexually transmitted diseases
Journal Article
Development (Cambridge), ISSN 0950-1991, 07/2017, Volume 144, Issue 14, pp. 2618 - 2628
Mechanisms that regulate tissue-specific progenitors for maintenance and differentiation during development are poorly understood. Here, we demonstrate that... 
P21/Cdkn1a | Mouse | Progenitor cell fate | Sin3a | Foregut endoderm | Epithelial-mesenchymal signaling | G1 arrest | COMPLEX | HISTONE DEACETYLASE ACTIVITY | TRANSCRIPTIONAL REPRESSION | BRANCHING MORPHOGENESIS | DEVELOPMENTAL BIOLOGY | LARGE GENE LISTS | SENESCENT HUMAN-FIBROBLASTS | MULTIPLE ROLES | p21/Cdkn1a | DIFFERENTIATION | EXPRESSION | MOUSE LUNG | Embryonic Stem Cells - metabolism | Embryonic Stem Cells - cytology | Epithelial Cells - metabolism | Endoderm - embryology | Lung - cytology | Cyclin-Dependent Kinase Inhibitor p21 - genetics | Repressor Proteins - deficiency | Endoderm - cytology | Gene Expression Regulation, Developmental | Cyclin-Dependent Kinase Inhibitor p21 - metabolism | Female | Cell Differentiation | Lung - metabolism | Epithelial Cells - cytology | Cell Lineage - genetics | Repressor Proteins - metabolism | Animals, Newborn | Signal Transduction | Repressor Proteins - genetics | Cyclin-Dependent Kinase Inhibitor p18 - metabolism | Cell Lineage - physiology | Endoderm - metabolism | Mice, Knockout | Pregnancy | Cell Cycle Checkpoints | Animals | Cyclin-Dependent Kinase Inhibitor p18 - genetics | Organogenesis - genetics | Lung - embryology | Mice | Organogenesis - physiology | Neonates | Senescence | Mesenchyme | Mesoderm | Progenitor cells | Morphogenesis | Atrophy | Cell fate | Developmental stages | Lungs | Stem cells | Cell cycle | Endoderm | Foregut | G1 phase | Cdkn1a | p21
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, p. e77447
Chlamydia pneumoniae (CP) lung infection can induce chronic lung inflammation and is associated with not only acute asthma but also COPD exacerbations.... 
BACTERIAL CLEARANCE | STRAIN-TWAR | REACTIVATION | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | ALVEOLAR MACROPHAGES | ASTHMA | MACROPHAGE POLARIZATION | ASSOCIATION | PULMONARY-FIBROSIS | CURRENT KNOWLEDGE | Lung - microbiology | Macrophages - transplantation | Cell Count | Dendritic Cells - immunology | Dendritic Cells - pathology | Adoptive Transfer | Chlamydia Infections - immunology | Chlamydia Infections - pathology | Chlamydial Pneumonia - immunology | B-Lymphocytes - pathology | T-Lymphocytes - pathology | Macrophages - immunology | Cytokines - immunology | Lung - pathology | Macrophages - classification | Macrophages - pathology | Chlamydial Pneumonia - microbiology | Mice, Inbred C57BL | Bacterial Load | Chlamydial Pneumonia - pathology | Chlamydophila pneumoniae - pathogenicity | Animals | B-Lymphocytes - immunology | Chlamydia Infections - microbiology | Fibrosis | T-Lymphocytes - immunology | Mice | Chronic Disease | Cytokines - biosynthesis | Lung - immunology | Chlamydophila pneumoniae - immunology | Medical research | Pneumonia | Cytokines | Chlamydia | Bacterial pneumonia | Medicine, Experimental | Antigen presenting cells | Inflammation | Asthma | Pediatrics | Animal models | Sexually transmitted diseases--STD | Chronic infection | Infections | Macrophages | Adoptive transfer | Inflammatory diseases | Signal transduction | Immunology | Rodents | Animal tissues | Atherosclerosis | Clusters | Bacteria | Chronic obstructive pulmonary disease | Bronchitis | Wound healing | Bacterial infections | Dendritic cells | Bronchus | Lymphoid tissue | Medicine | Pathology | Infectious diseases | Pulmonary fibrosis | Lungs | Sexually transmitted diseases
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 03/2009, Volume 24, Issue 3, pp. 398 - 410
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e48655
Plasmacytoid dendritic cells (pDCs) are known for their robust antiviral response and their pro-tolerance effects towards allergic diseases and tissue... 
SURVIVAL | ACTIVATION | COLONY-STIMULATING FACTOR | NK CELLS | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | MOUSE | RESISTANCE | Diphtheria Toxin - pharmacology | Lung - microbiology | Dendritic Cells - immunology | Humans | Bronchoalveolar Lavage Fluid - immunology | Interferon-gamma - metabolism | Bronchoalveolar Lavage Fluid - microbiology | Intercellular Signaling Peptides and Proteins - metabolism | Flow Cytometry | T-Lymphocytes - metabolism | Chlamydial Pneumonia - immunology | Dendritic Cells - drug effects | Female | Membrane Proteins - metabolism | Interleukin-6 - metabolism | B-Lymphocytes - metabolism | Dendritic Cells - metabolism | Lung - pathology | Chlamydial Pneumonia - microbiology | Mice, Inbred C57BL | Intercellular Signaling Peptides and Proteins - genetics | Lymph Nodes - metabolism | Membrane Proteins - immunology | Mice, Transgenic | Diphtheria Toxin - immunology | Lymph Nodes - immunology | Heparin-binding EGF-like Growth Factor | Immunity, Innate - immunology | Animals | B-Lymphocytes - immunology | Interferon-gamma - immunology | Interleukin-6 - immunology | Cell Line, Tumor | Ligands | T-Lymphocytes - immunology | Mice | Intercellular Signaling Peptides and Proteins - immunology | Lung - immunology | Chlamydophila pneumoniae - immunology | Lymph Nodes - microbiology | Medical research | Pneumonia | Immune response | Bacterial infections | Cytokines | Dendritic cells | Bacterial pneumonia | Inflammation | Research | T cells | Chlamydia | Medicine, Experimental | Health aspects | Pediatrics | Immune clearance | Lymphocytes T | Infections | Allergic diseases | Inflammatory diseases | Lymph nodes | Recruitment | Sexually transmitted diseases | Immunology | Granulocytes | Listeria | Lymphocytes | Bacteria | Cellular manufacture | Pathogens | Antigens | FLT3L protein | Mortality | T cell receptors | Immunological tolerance | Studies | Drainage | Pathology | Infectious diseases | Lymphocytes B | Lungs | Viral infections | Lymph
Journal Article
Journal of Cellular Physiology, ISSN 0021-9541, 10/2007, Volume 213, Issue 1, pp. 126 - 136
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2010, Volume 402, Issue 1, p. 1
a* LPS-stimulated ERK activation is specifically impaired in cot/tpl2.sup.-/- mast cells. a* LPS-induced expression of Th2 cytokines is impaired in... 
Mitogens
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 11/2010, Volume 402, Issue 1, pp. 1 - 6
Cot/Tpl2, a member of MAP kinase kinase kinase (MAPKKK), is indispensable for the ERK activation, as well as the production of TNF- alpha , IL-1b, IL-23, and... 
Allergic diseases
Journal Article