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Lancet, The, ISSN 0140-6736, 2014, Volume 383, Issue 9911, pp. 60 - 68
Summary Background Proprotein convertase subtilisin/kexin type 9 (PCSK9) binds to LDL receptors, leading to their degradation. Genetics studies have shown that... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | DENSITY-LIPOPROTEIN CHOLESTEROL | DOUBLE-STRANDED-RNA | PLASMA-CHOLESTEROL | METAANALYSIS | CARDIOVASCULAR-DISEASE | MONOCLONAL-ANTIBODY | HYPERCHOLESTEROLEMIA | STATINS | AMG 145 | ATORVASTATIN | Single-Blind Method | Serine Endopeptidases - biosynthesis | Humans | Middle Aged | RNA, Small Interfering - pharmacology | RNA, Small Interfering - adverse effects | Cholesterol, LDL - drug effects | Male | Healthy Volunteers | Proprotein Convertases - genetics | Dose-Response Relationship, Drug | Proprotein Convertases - biosynthesis | RNA Interference | Serine Endopeptidases - blood | Serine Endopeptidases - genetics | Adult | Cholesterol, LDL - blood | Female | Proprotein Convertases - blood | RNA, Small Interfering - administration & dosage | Genetic Therapy - adverse effects | Genetic Therapy - methods | Proprotein Convertase 9 | Enzymes | Research | Gene mutations | Properties | Gene expression | Identification and classification | Medical research | RNA | Low density lipoproteins | Anticholesteremic agents | Clinical trials | Aluminum compounds | Coronary heart disease | Cholesterol | Hypercholesterolemia | Analysis | Medicine, Experimental | Product development | Trans fatty acids | Blood proteins | Studies | Heart | Nanoparticles | Plasma | Nutrition research | Cardiovascular disease | Lipids | Mutation | Drug dosages | Statins | Index Medicus | Abridged Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2013, Volume 369, Issue 9, pp. 819 - 829
Journal Article
by Thomas, H.S and Weiser, T.G and Drake, T.M and Knight, S.R and Fairfield, C and Ademuyiwa, A.O and Aguilera, M.L and Alexander, P and Al-Saqqa, S.W and Borda-Luque, G and Costas-Chavarri, A and Ntirenganya, F and Fitzgerald, J.E and Fergusson, S.J and Glasbey, J and Ingabire, J.C.A and Ismaïl, L and Salem, H.K and Kojo, A.T.T and Lapitan, M.C and Lilford, R and Mihaljevic, A.L and Morton, D and Mutabazi, A.Z and Nepogodiev, D and Adisa, A.O and Ots, R and Pata, F and Pinkney, T and Qureshi, A.U and la Medina, A.R and Rayne, S and Shaw, C.A and Shu, S and Spence, R and Smart, N and Tabiri, S and Bhangu, A and Harrison, E.M and Verjee, A and Runigamugabo, E and Altamini, A and Cornick, J and Jaffry, Z and Khatri, C and Kirby, A and Mohan, M and Recinos, G and Søreide, K and Gobin, N and Freitas, A.V and Hall, N and Kim, S.H and Negida, A and Khairy, H and Chapman, S.J and Arnaud, A.P and Manipal, C.E and Amandito, R and Shawki, M and Hanrahan, M and Zilinskas, J and Roslani, A.C and Goh, C.C and Irwin, G and Luque, L and Shiwani, H and Altamimi, A and Alsaggaf, M.U and Jeyakumar, J and Cengiz, Y and Raptis, D.A and Glasbey, J.C and Modolo, M.M and Iyer, D and King, S and Arthur, T and Nahar, S.N and Waterman, A and Walsh, L.I and Agarwal, A and Zani, A and Firdouse, M and Rouse, T and Liu, Q and Correa, J.C and Talving, P and Worku, M and Arnaud, A and Kalles, V and Kumar, B and Kumar, S and Quek, R and Ansaloni, L and Altibi, A and Venskutonis, D and Poskus, T and Whitaker, J and Msosa, V and Tew, Y.Y and ... and GlobalSurg Collaborative
British Journal of Surgery, ISSN 0007-1323, 01/2019, Volume 106, Issue 2, pp. e103 - e112
Journal Article