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Advances in experimental medicine and biology, ISSN 0065-2598, 2019, Volume 1122, p. 187
Mural cells known as pericytes envelop the endothelial layer of microvessels throughout the body and have been described to have tissue-specific functions.... 
Heart | Microvessels - cytology | Regeneration | Animals | Humans | Pericytes - cytology | Neovascularization, Physiologic | Myocardium - cytology
Journal Article
Circulation, ISSN 0009-7322, 11/2018, Volume 138, Issue Suppl_1 Suppl 1, pp. A14869 - A14869
Pericytes (PCs) are mural cells that envelop the endothelial cells (ECs) of microvessels throughout the body. As per studies in the brain, PCs are known to... 
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 2017, Volume 292, Issue 31, pp. 12787 - 12800
Stress-induced p38 mitogen-activated protein kinase (MAPK) activity is implicated in pathological remodeling in the heart. For example, constitutive p38 MAPK... 
Endothelium, Vascular - cytology | Myocardial Ischemia - metabolism | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Myocytes, Cardiac - secretion | Male | Sp1 Transcription Factor - metabolism | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor A - secretion | Vascular Endothelial Growth Factor Receptor-2 - genetics | Cell Hypoxia | Sp1 Transcription Factor - antagonists & inhibitors | Mitogen-Activated Protein Kinase 14 - metabolism | RNA Interference | Vascular Endothelial Growth Factor A - agonists | Human Umbilical Vein Endothelial Cells - cytology | Vascular Endothelial Growth Factor Receptor-2 - agonists | Mitogen-Activated Protein Kinase 14 - chemistry | Animals, Newborn | Recombinant Proteins - metabolism | Myocytes, Cardiac - cytology | Cells, Cultured | Gene Expression Regulation | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Mice, Transgenic | Mitogen-Activated Protein Kinase 14 - genetics | Rats, Sprague-Dawley | Mice, Knockout | Myocardial Ischemia - pathology | Myocardial Revascularization | Myocytes, Cardiac - pathology | Animals | Sp1 Transcription Factor - genetics | Endothelium, Vascular - metabolism | Myocytes, Cardiac - metabolism | Endothelium, Vascular - pathology | Enzyme Activation | Sus scrofa | Crosses, Genetic | cross-talk | angiogenesis | cardiomyocyte | vascular endothelial growth factor (VEGF) | cardiac hypertrophy | p38 MAPK | Cell Biology
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2009, Volume 386, Issue 4, p. 612
Previous studies have demonstrated a role for angiotensin II (AngII) and myofibroblasts (myoFb) in cardiac fibrosis. However, the role of PKC-[delta] in AngII... 
Journal Article
Journal of visualized experiments : JoVE, ISSN 1940-087X, 08/2019, Issue 150
Pericytes, perivascular cells of microvessels and capillaries, are known to play a part in angiogenesis, vessel stabilization, and endothelial barrier... 
Medicine | CELLS | primary cell culture | pericytes | cell isolation | MULTIDISCIPLINARY SCIENCES | Issue 150 | vascular biology | SKELETAL | perivascular cells | cardiac
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2011, Volume 51, Issue 3, pp. 337 - 346
The platelet derived growth factor receptor (PDGFR) is an important target for novel anti-cancer therapeutics, but agents targeting PDGFR have been associated... 
Angiogenesis | MicroRNA | Receptor tyrosine kinase | Cardiac myocyte | Platelet derived growth factor
Journal Article
Journal Article
Journal Article
Pharmacology Research & Perspectives, ISSN 2052-1707, 12/2018, Volume 6, Issue 6, pp. e00442 - n/a
Journal Article
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2011, Volume 51, Issue 3, pp. 337 - 346
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2010, Volume 120, Issue 2, p. 472
PDGFR is an important target for novel anticancer therapeutics because it is overexpressed in a wide variety of malignancies. Recently, however, several... 
Heart failure | Antimitotic agents | Complications and side effects | Care and treatment | Platelet-derived growth factor | Physiological aspects | Dosage and administration | Research | Antineoplastic agents | Risk factors | Cancer
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 11/2004, Volume 311, Issue 2, pp. 691 - 699
The role of endothelin-1 (ET) in tissue remodeling/fibrogenesis has been demonstrated in various in vitro and in vivo models. Our previous studies have... 
ALPHA-1(I) GENE-EXPRESSION | CHRONIC HEART-FAILURE | CELLS | DE-NOVO | ACTIVATION | RECEPTOR BLOCKADE | RAT | PATHWAY | TRANSCRIPTION FACTOR SP1 | PHARMACOLOGY & PHARMACY | FIBROBLASTS
Journal Article
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