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science & technology (59) 59
apoptosis (53) 53
life sciences & biomedicine (50) 50
humans (48) 48
animals (45) 45
mitochondria (32) 32
cell biology (30) 30
biochemistry & molecular biology (25) 25
mice (25) 25
proteins (21) 21
mitochondria - metabolism (17) 17
bcl-2 family (15) 15
mitochondrial membranes - metabolism (15) 15
bcl-2-associated x protein - metabolism (14) 14
proto-oncogene proteins c-bcl-2 - metabolism (14) 14
biological phenomena, cell phenomena, and immunity (13) 13
permeability (13) 13
bcl-2 homologous antagonist-killer protein - metabolism (12) 12
cell death (12) 12
tumor suppressor protein p53 - metabolism (12) 12
cancer (11) 11
medical colleges (11) 11
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metabolism (8) 8
mice, inbred c57bl (8) 8
apoptosis regulatory proteins - metabolism (7) 7
bcl-2-associated x protein - chemistry (7) 7
cells (7) 7
hela cells (7) 7
models, biological (7) 7
momp (7) 7
protein structure, tertiary (7) 7
amino acid sequence (6) 6
analysis (6) 6
apoptosis - physiology (6) 6
bax (6) 6
cell survival (6) 6
cells, cultured (6) 6
gene expression regulation (6) 6
lipids (6) 6
melanoma (6) 6
membrane proteins - metabolism (6) 6
mitochondrial dna (6) 6
mitochondrial dynamics (6) 6
mutation (6) 6
oncology (6) 6
protein binding (6) 6
bcl-2-associated x protein (5) 5
bcl-2-like protein 11 (5) 5
biochemistry (5) 5
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biology (5) 5
cell proliferation (5) 5
cytochromes c - metabolism (5) 5
homeostasis (5) 5
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mice, knockout (5) 5
mitochondria - genetics (5) 5
mitochondrial proteins - metabolism (5) 5
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molecular sequence data (5) 5
proto-oncogene proteins c-bcl-2 - chemistry (5) 5
tumor suppressor protein p53 - genetics (5) 5
apoptosis - drug effects (4) 4
apoptosis - genetics (4) 4
apoptosis regulatory proteins - chemistry (4) 4
bcl-2 protein (4) 4
bcl-x protein (4) 4
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fundamental and applied biological sciences. psychology (4) 4
gene expression (4) 4
kinetics (4) 4
melanoma - pathology (4) 4
mice, transgenic (4) 4
molecular and cellular biology (4) 4
organelles (4) 4
p53 (4) 4
pathology (4) 4
phosphorylation (4) 4
proto-oncogene proteins - chemistry (4) 4
transcription, genetic (4) 4
tumor suppressor protein p53 - chemistry (4) 4
bak (3) 3
bcl-2 homologous antagonist-killer protein - chemistry (3) 3
bcl-2 homologous antagonist-killer protein - genetics (3) 3
bcl-2 proteins (3) 3
bcl-2-associated x protein - genetics (3) 3
bh3 interacting domain death agonist protein - chemistry (3) 3
bh3 interacting domain death agonist protein - metabolism (3) 3
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41. Full Text Late-onset megaconial myopathy in mice lacking group i Paks
by Joseph, Giselle A and Hung, Margaret and Goel, Aviva J and Hong, Mingi and Rieder, Marysia-Kolbe and Beckmann, Noam D and Serasinghe, Madhavika N and Chipuk, Jerry E and Devarakonda, Parvathi M and Goldhamer, David J and Aldana-Hernandez, Paulina and Curtis, Jonathan and Jacobs, René L and Krauss, Robert S
Skeletal muscle, ISSN 2044-5040, 02/2019, Volume 9, Issue 1, pp. 5 - 5
Pak kinase | Mitochondria | Choline kinase | Skeletal muscle | Myopathy | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Choline Kinase - metabolism | Mitochondrial Myopathies - metabolism | p21-Activated Kinases - genetics | Muscle, Skeletal - ultrastructure | Male | Muscle, Skeletal - metabolism | Mitochondria - metabolism | p21-Activated Kinases - metabolism | Mitochondria - ultrastructure | Mitochondrial Myopathies - pathology | Mice, Knockout | Mitochondrial Myopathies - genetics | Animals | Mitochondrial Proteins - metabolism | Female | Genetic disorders | Analysis | Choline | Muscles | G proteins | Mass spectrometry | Protein kinases | Cdc42 protein | Phosphorylation | Transcription | Homeostasis | Glucose | Kinases | Muscular dystrophy | Western blotting | Defects | Cell adhesion & migration | Proteins | Electron transport chain | Genotype & phenotype | Polarity | Degeneration | Age | Phenotypes | Congenital diseases | Rac1 protein | Protein deficiency | Electron microscopy | Metabolism | Gene expression | Insulin | Myoblasts | Musculoskeletal system | Fibrosis | Stem cells | Cytoskeleton | Mutation | Immunofluorescence | Index Medicus
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42. Full Text Abstract 375: Origins of fractional control in regulated cell death
by Santos, Luis C and Vogel, Robert and Chipuk, Jerry E and Birtwistle, Marc and Stolovitzky, Gustavo and Meyer, Pablo
Cancer research (Chicago, Ill.), ISSN 0008-5472, 07/2018, Volume 78, Issue 13 Supplement, pp. 375 - 375
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43. Full Text Pharmacologic activation of p53 elicits Bax-dependent apoptosis in the absence of transcription
by Chipuk, Jerry E and Maurer, Ulrich and Green, Douglas R and Schuler, Martin
Cancer cell, ISSN 1535-6108, 2003, Volume 4, Issue 5, pp. 371 - 381
Oncology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Receptors, Estrogen - metabolism | Humans | Aza Compounds - pharmacology | Recombinant Fusion Proteins - metabolism | Cell Nucleus - metabolism | Cloning, Molecular | Transcription, Genetic | Protein Synthesis Inhibitors - pharmacology | Tumor Cells, Cultured | Fibroblasts - metabolism | Proto-Oncogene Proteins - metabolism | Cytochromes c - metabolism | Cells, Cultured | Tumor Suppressor Protein p53 - metabolism | Mitochondria - metabolism | bcl-2-Associated X Protein | Tumor Suppressor Protein p53 - drug effects | Protein Transport | Bridged Bicyclo Compounds, Heterocyclic - pharmacology | Animals | Tamoxifen - pharmacology | Tamoxifen - analogs & derivatives | Mice | Apoptosis - physiology | Mutation | Proto-Oncogene Proteins c-bcl-2 | Index Medicus
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44. Full Text Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF(V600E) Melanoma
by Wieder, Shira Y and Serasinghe, Madhavika N and Sung, Julie C and Choi, Daniel C and Birge, Miriam B and Yao, Jonathan L and Bernstein, Emily and Celebi, Julide T and Chipuk, Jerry E
Journal of investigative dermatology, ISSN 0022-202X, 10/2015, Volume 135, Issue 10, pp. 2544 - 2547
Life Sciences & Biomedicine | Dermatology | Science & Technology | Immunohistochemistry | Skin Neoplasms - pathology | Dysplastic Nevus Syndrome - genetics | Microtubule-Associated Proteins - genetics | Tissue Culture Techniques | Humans | Transcriptional Activation | Gene Expression Regulation, Neoplastic | Cell Survival - genetics | Reference Values | Mitochondrial Proteins - genetics | Melanoma - pathology | Sampling Studies | GTP Phosphohydrolases - genetics | Melanoma - genetics | Mitochondrial Proteins - metabolism | Proto-Oncogene Proteins B-raf - genetics | Skin Neoplasms - genetics | Biopsy, Needle | Dysplastic Nevus Syndrome - pathology | Index Medicus
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45. Full Text Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAF V600E Melanoma
by Wieder, Shira Y and Serasinghe, Madhavika N and Sung, Julie C and Choi, Daniel C and Birge, Miriam B and Yao, Jonathan L and Bernstein, Emily and Celebi, Julide T and Chipuk, Jerry E
Journal of investigative dermatology, ISSN 0022-202X, 10/2015, Volume 135, Issue 10, pp. 2544 - 2547
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46. Full Text Mechanism of Apoptosis Induction by Inhibition of the Anti-Apoptotic BCL-2 Proteins
by Jerry E. Chipuk and John C. Fisher and Christopher P. Dillon and Richard W. Kriwacki and Tomomi Kuwana and Douglas R. Green
Proceedings of the National Academy of Sciences - PNAS, ISSN 0027-8424, 12/2008, Volume 105, Issue 51, pp. 20327 - 20332
Proteins | Molecules | Mitochondria | Complementary DNA | Neurons | Mitochondrial membranes | HeLa cells | Cytochromes | Apoptosis | Tumors | MOMP | BCL-2 family | PUMA | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Animals | Mitochondrial Membranes | Apoptosis Regulatory Proteins - antagonists & inhibitors | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Proto-Oncogene Proteins c-bcl-2 - antagonists & inhibitors | Mice | Permeability | bcl-2 Homologous Antagonist-Killer Protein - metabolism | Physiological aspects | Research | Apoprotein | Membranes | Cells | Index Medicus | Biological Sciences | mitochondria
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47. Full Text Physiological and Pharmacological Control of BAK, BAX, and Beyond
by Luna-Vargas, Mark P.A and Chipuk, Jerry Edward
Trends in cell biology, ISSN 0962-8924, 2016, Volume 26, Issue 12, pp. 906 - 917
Pathology | apoptosis | mitochondrial outer membrane permeabilization | BCL-2 family | mitochondria | BH3 mimetics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Amino Acid Sequence | bcl-2-Associated X Protein - chemistry | Animals | Models, Biological | Humans | Membrane Potential, Mitochondrial | bcl-2-Associated X Protein - metabolism | Mitochondria - metabolism | bcl-2 Homologous Antagonist-Killer Protein - metabolism | bcl-2 Homologous Antagonist-Killer Protein - chemistry | Apoptosis | Proteins | Physiological aspects | Medical colleges | Membranes | Chronic lymphatic leukemia | Bax protein | Bcl-2 protein | Leukemia | Pharmacology | Permeability | Lymphatic leukemia | Lymphoma | Organelles | Disease control | Mitochondria | Lymphocytes B | Major outer membrane protein | Index Medicus | MOMP
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48. Full Text Activation of the Mitochondrial Fragmentation Protein DRP1 Correlates with BRAFV600E Melanoma
by Wieder, Shira Y and Serasinghe, Madhavika N and Sung, Julie C and Choi, Daniel C and Birge, Miriam B and Yao, Jonathan L and Bernstein, Emily and Celebi, Julide T and Chipuk, Jerry E
Journal of investigative dermatology, ISSN 0022-202X, 10/2015, Volume 135, Issue 10, pp. 2544 - 2547
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49. Full Text Born to be alive: A role for the BCL-2 family in melanoma tumor cell survival, apoptosis, and treatment
by Anvekar, Rina A and Asciolla, James J and Missert, Derek J and Chipuk, Jerry E
Frontiers in oncology, ISSN 2234-943X, 2011, Volume 1, Issue 34
Chemotherapy | Mitochondria | BCL-2 family | Melanoma | Apoptosis | Cancer | chemotherapy | BCL-2 Family
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50. Full Text p53's Believe It or Not: Lessons on Transcription-Independent Death
by Chipuk, Jerry E and Green, Douglas R
Journal of clinical immunology, ISSN 0271-9142, 9/2003, Volume 23, Issue 5, pp. 355 - 361
transcription-independent | Medical Microbiology | Biomedicine | Immunology | mutants | mitochondria | Internal Medicine | Infectious Diseases | apoptosis | p53 | Mitochondria | Transcription-independent | Apoptosis | Mutants | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Ageing, cell death | Animals | Mitochondria - genetics | Signal Transduction | Humans | Tumor Suppressor Protein p53 - metabolism | Transcription, Genetic | Cell Membrane - genetics | Cell Membrane - metabolism | Mitochondria - metabolism | Tumor Suppressor Protein p53 - chemistry | Tumor Suppressor Protein p53 - genetics | Index Medicus
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51. Full Text Survival of HER2-Positive Breast Cancer Cells: Receptor Signaling to Apoptotic Control Centers
by Fink, Marc Y and Chipuk, Jerry E
Genes & cancer, ISSN 1947-6019, 03/2013, Volume 4, Issue 5-6, pp. 187 - 195
trastuzumab | lapatinib | mTOR | BCL-2 | AKT | BAD | Review
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52. Full Text Repeated hypoglycemia remodels neural inputs and disrupts mitochondrial function to blunt glucose-inhibited GHRH neuron responsiveness
by Bayne, Mitchell and Alvarsson, Alexandra and Devarakonda, Kavya and Li, Rosemary and Jimenez-Gonzalez, Maria and Garibay, Darline and Conner, Kaetlyn and Varghese, Merina and Serasinghe, Madhavika N and Chipuk, Jerry E and Hof, Patrick R and Stanley, Sarah A
JCI insight, 11/2020, Volume 5, Issue 21
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Index Medicus | Metabolism | Neuroscience
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53. Full Text Activation of Nrf2 Is Required for Normal and ChREBPα-Augmented Glucose-Stimulated β-Cell Proliferation
by Kumar, Anil and Kumar, Anil and Katz, Liora S and Katz, Liora S and Schulz, Anna M and Schulz, Anna M and Kim, Misung and Kim, Misung and Honig, Lee B and Honig, Lee B and Li, Lucy and Li, Lucy and Davenport, Bennett and Davenport, Bennett and Homann, Dirk and Homann, Dirk and Garcia-Ocaña, Adolfo and Garcia-Ocaña, Adolfo and Herman, Mark A and Herman, Mark A and Haynes, Cole M and Haynes, Cole M and Chipuk, Jerry E and Chipuk, Jerry E and Scott, Donald K and Scott, Donald K
Diabetes (New York, N.Y.), ISSN 0012-1797, 08/2018, Volume 67, Issue 8, pp. 1561 - 1575
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Mitochondrial Dynamics | NF-E2-Related Factor 2 - antagonists & inhibitors | Cell Proliferation | Transcription Factors - chemistry | Humans | NF-E2-Related Factor 2 - agonists | Recombinant Fusion Proteins - metabolism | Protein Subunits - metabolism | Organelle Biogenesis | Insulin-Secreting Cells - metabolism | RNA Interference | Luminescent Proteins - chemistry | NF-E2-Related Factor 2 - genetics | Insulin-Secreting Cells - cytology | Nuclear Proteins - genetics | Insulin Secretion | Protein Subunits - genetics | Tissue Culture Techniques | Mice, Inbred C57BL | Gene Expression Regulation | Oxygen Consumption | Rats | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - chemistry | Mice, Transgenic | Nuclear Proteins - metabolism | Recombinant Fusion Proteins - chemistry | Transcription Factors - genetics | Nuclear Proteins - chemistry | Transcription Factors - metabolism | Insulin - metabolism | Animals | NF-E2-Related Factor 2 - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Cell Line, Tumor | Glucose - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Luminescent Proteins - genetics | Mice | Protein Subunits - chemistry | Cadaver | Luminescent Proteins - metabolism | Index Medicus | Abridged Index Medicus | 0710 | Islet Studies
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54. Full Text Inter-organellar communication with mitochondria regulates both the intrinsic and extrinsic pathways of apoptosis
by Renault, Thibaud T and Chipuk, Jerry E
Communicative & integrative biology, ISSN 1942-0889, 03/2013, Volume 6, Issue 2, pp. e22872 - e22872
BCL-2 family | sphingolipids | mitochondria | apoptosis | organelles | cytochrome c release | endoplasmic reticulum | Addendum
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