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1. Full Text Rational, biologically based treatment of EGFR -mutant non-small-cell lung cancer
by Chmielecki, Juliann and Pao, William
Nature reviews. Cancer, ISSN 1474-175X, 11/2010, Volume 10, Issue 11, pp. 760 - 774
Life Sciences & Biomedicine | Oncology | Science & Technology | Lung Neoplasms - genetics | Lung Neoplasms - drug therapy | Receptor, Epidermal Growth Factor - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Protein Kinase Inhibitors - therapeutic use | Humans | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Drug Resistance, Neoplasm | Antineoplastic Agents - therapeutic use | Carcinoma, Non-Small-Cell Lung - drug therapy | Mutation | Protein-Tyrosine Kinases - antagonists & inhibitors | Care and treatment | Epidermal growth factor | Physiological aspects | Genetic aspects | Metastasis | Research | Lung cancer, Non-small cell | Risk factors | Index Medicus
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2. Full Text DNA Sequencing of Cancer: What Have We Learned?
by Chmielecki, Juliann and Meyerson, Matthew
Annual review of medicine, ISSN 0066-4219, 1/2014, Volume 65, Issue 1, pp. 63 - 79
genomics | pathways | cancer | mutations | rearrangements | Mutations | Pathways | Genomics | Rearrangements | Cancer | Neoplasms - metabolism | Cell Cycle - genetics | Epigenesis, Genetic | Humans | Signal Transduction - genetics | Transcription Factors - genetics | Neoplasms - genetics | DNA Mutational Analysis | Oncogene Fusion | Gene Rearrangement | Oncogene Protein v-akt - genetics | Mitogen-Activated Protein Kinases - genetics | Transcription, Genetic | Oncogene Protein v-akt - metabolism | Mitogen-Activated Protein Kinases - metabolism | RNA - metabolism | Genetic aspects | Research | Nucleotide sequencing | DNA sequencing | Signal transduction | Cell cycle | Genomes | Metabolism | Deoxyribonucleic acid--DNA | Index Medicus
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3. Full Text Anchored multiplex PCR for targeted next-generation sequencing
by Zheng, Zongli and Liebers, Matthew and Zhelyazkova, Boryana and Cao, Y and Panditi, Divya and Lynch, Kerry D and Chen, Juxiang and Robinson, Hayley E and Shim, Hyo Sup and Chmielecki, Juliann and Pao, William and Engelman, Jeffrey A and Iafrate, A John and Le, Long Phi
Nature medicine, ISSN 1078-8956, 11/2014, Volume 20, Issue 12, pp. 1479 - 1484
Lung Neoplasms - genetics | Paraffin Embedding | Gene Fusion - genetics | Thyroid Neoplasms - genetics | Multiplex Polymerase Chain Reaction - methods | Glioblastoma - genetics | Humans | Polymerase Chain Reaction | Cholangiocarcinoma - genetics | Bile Duct Neoplasms - genetics | Gene Rearrangement - genetics | Sequence Analysis, DNA - methods | Polymerase chain reaction | Usage | Research | Nucleotide sequencing | Methods | DNA sequencing | Genetics | Biological assays | Cancer | Tumors | Index Medicus | Medicin och hälsovetenskap
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4. Full Text Whole-exome sequencing identifies a recurrent NAB2-STAT6 fusion in solitary fibrous tumors
by Chmielecki, Juliann and Crago, Aimee M and Rosenberg, Mara and O'Connor, Rachael and Walker, Sarah R and Ambrogio, Lauren and Auclair, Daniel and McKenna, Aaron and Heinrich, Michael C and Frank, David A and Meyerson, Matthew
Nature genetics, ISSN 1061-4036, 02/2013, Volume 45, Issue 2, pp. 131 - 132
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Usage | Identification and classification | Health aspects | Gene fusion | Exome sequencing | Medical research | Genomics | Genomes | Mutation | Gene expression | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
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5. Full Text Analysis of 100,000 human cancer genomes reveals the landscape of tumor mutational burden
by Chalmers, Zachary R and Connelly, Caitlin F and Fabrizio, David and Gay, Laurie and Ali, Siraj M and Ennis, Riley and Schrock, Alexa and Campbell, Brittany and Shlien, Adam and Chmielecki, Juliann and Huang, Franklin and He, Yuting and Sun, James and Tabori, Uri and Kennedy, Mark and Lieber, Daniel S and Roels, Steven and White, Jared and Otto, Geoffrey A and Ross, Jeffrey S and Garraway, Levi and Miller, Vincent A and Stephens, Phillip J and Frampton, Garrett M
Genome medicine, ISSN 1756-994X, 04/2017, Volume 9, Issue 1, pp. 34 - 34
Tumor mutational burden | PMS2 | Mismatch repair | Cancer genomics | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Neoplasms - metabolism | Age Factors | Humans | Middle Aged | Exome | Young Adult | Neoplasms - genetics | Cell Transformation, Neoplastic - genetics | DNA Mutational Analysis | DNA, Neoplasm | Adolescent | Aged, 80 and over | Adult | Aged | Mismatch Repair Endonuclease PMS2 | Mutation | Genome, Human | Neoplasms - pathology | Child | Neoplasms - epidemiology | DNA damage | Gene regulation | Melanoma | Genomes | Gene expression | Patients | Cancer therapies | DNA repair | Promoters | Defects | Proteins | Immune checkpoint | Immunotherapy | Tumorigenesis | Bioinformatics | Deoxyribonucleic acid--DNA | Tumors | Index Medicus
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6. Full Text New strategies in overcoming acquired resistance to epidermal growth factor receptor tyrosinekinase inhibitors in lung cancer
by Oxnard, Geoffrey R and Arcila, Maria E and Chmielecki, Juliann and Ladanyi, Marc and Miller, Vincent A and Pao, William
Clinical cancer research, ISSN 1078-0432, 09/2011, Volume 17, Issue 17, pp. 5530 - 5537
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7. Full Text The distribution of BRAF gene fusions in solid tumors and response to targeted therapy
by Ross, Jeffrey S and Wang, Kai and Chmielecki, Juliann and Gay, Laurie and Johnson, Adrienne and Chudnovsky, Jacob and Yelensky, Roman and Lipson, Doron and Ali, Siraj M and Elvin, Julia A and Vergilio, Jo‐Anne and Roels, Steven and Miller, Vincent A and Nakamura, Brooke N and Gray, Adam and Wong, Michael K and Stephens, Philip J
International journal of cancer, ISSN 0020-7136, 02/2016, Volume 138, Issue 4, pp. 881 - 890
targeted therapy | pilocytic astrocytoma | Sptizoid melanoma | pancreatic acinar carcinoma | comprehensive genomic profiling | cancer | NGS | BRAF fusions | solid tumors | Life Sciences & Biomedicine | Oncology | Science & Technology | Niacinamide - analogs & derivatives | Humans | Middle Aged | Transcriptome | Child, Preschool | Infant | Male | Antineoplastic Agents - therapeutic use | Gene Expression Profiling | Young Adult | Neoplasms - genetics | Aged, 80 and over | Adult | Female | Child | Molecular Targeted Therapy - methods | Pyrimidinones - therapeutic use | Niacinamide - therapeutic use | Phenylurea Compounds - therapeutic use | Treatment Outcome | Neoplasms - drug therapy | Oncogene Proteins, Fusion - genetics | Protein Kinase Inhibitors - therapeutic use | Proto-Oncogene Proteins B-raf - genetics | Adolescent | Aged | Pyridones - therapeutic use | Thyroid cancer | Gliomas | Pancreatic cancer | Genes | Colorectal cancer | Melanoma | Genetic research | Lung cancer, Non-small cell | Kinases | Tumors | Index Medicus | Cancer Genetics and Epigenetics
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