X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
positive allosteric modulator (3) 3
aldehyde oxidase (2) 2
chemistry, medicinal (2) 2
chemistry, organic (2) 2
index medicus (2) 2
iodine (2) 2
muscarinic acetylcholine receptor (2) 2
neurosciences (2) 2
structure-activity relationship (2) 2
5-ht (1) 1
5-ht2a (1) 1
activation (1) 1
adrenergic (1) 1
aldehydes (1) 1
amination (1) 1
amines - chemical synthesis (1) 1
amines - chemistry (1) 1
aminierung (1) 1
aminierungen (1) 1
article (1) 1
atypical (1) 1
atypical antipsychotics (1) 1
binding (1) 1
biochemistry & molecular biology (1) 1
c-h amination (1) 1
c-h functionalization (1) 1
c-h-funktionalisierung (1) 1
catalyzed intramolecular amination (1) 1
challenges (1) 1
chemical bonds (1) 1
chemistry (1) 1
chemistry, multidisciplinary (1) 1
cyclisation (1) 1
cyclization (1) 1
c−h functionalization (1) 1
d-2 (1) 1
decomposition (1) 1
diels-alder reactions (1) 1
discovery (1) 1
dopamine (1) 1
dopamine hypothesis (1) 1
drug discovery (1) 1
drugs (1) 1
functionalisation (1) 1
funktionalisierung (1) 1
generation (1) 1
heterocycle synthesis (1) 1
histamine (1) 1
hofmann-loffler reaction (1) 1
hydrogen (1) 1
hydrogen atom transfer (1) 1
iod (1) 1
iodides - chemistry (1) 1
late-stage functionalization (1) 1
lubrication and lubricants (1) 1
m (1) 1
m-4 (1) 1
mechanism (1) 1
medical colleges (1) 1
metabolites (1) 1
molecular structure (1) 1
natriumiodid (1) 1
nitrogen-centered radicals (1) 1
nuclear magnetic resonance (1) 1
optimization (1) 1
oxidases (1) 1
oxidation (1) 1
oxidation-reaction (1) 1
p-glycoprotein (1) 1
pharmacogenetics (1) 1
pharmacokinetics (1) 1
photochemistry, radiation chemistry, chemoluminescence (1) 1
photoredox catalysis (1) 1
physiological aspects (1) 1
positive allosteric modulators (1) 1
potentiators (1) 1
preclinical candidate (1) 1
pyridazines (1) 1
pyridine (1) 1
pyrrole derivatives (1) 1
pyrrolidin (1) 1
pyrrolidine (1) 1
pyrrolidines - chemistry (1) 1
radical chemistry (1) 1
radikalchemie (1) 1
receptor (1) 1
receptor occupancy (1) 1
remote h abstraction (1) 1
ring closure reactions, annulation reactions (1) 1
risperdal (1) 1
risperidone (1) 1
s-tetrazines (1) 1
schizophrenia (1) 1
series (1) 1
serotonin (1) 1
sodium iodides (1) 1
sodium-iodide (1) 1
strategy (1) 1
triiodid (1) 1
triiodide (1) 1
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Angewandte Chemie, ISSN 1433-7851, 08/2016, Volume 55, Issue 34, p. 9974
  The C[delta]-H amination of unactivated, secondary C-H bonds to form a broad range of functionalized pyrrolidines has been developed by a triiodide... 
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 08/2016, Volume 55, Issue 34, pp. 9974 - 9978
Journal Article
ACS Chemical Neuroscience, ISSN 1948-7193, 07/2018, Volume 9, Issue 7, pp. 1520 - 1529
After the identification of the influence of serotonergic receptors in ameliorating the negative symptoms associated with schizophrenia, atypical... 
serotonin | histamine | atypical | adrenergic | Risperdal | schizophrenia | 5-HT | Risperidone | dopamine | CHEMISTRY, MEDICINAL | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | D-2 | RECEPTOR OCCUPANCY | NEUROSCIENCES | ATYPICAL ANTIPSYCHOTICS | P-GLYCOPROTEIN | PHARMACOKINETICS | DRUGS | PHARMACOGENETICS | DOPAMINE HYPOTHESIS | BINDING | 5-HT2A
Journal Article
Angewandte Chemie, ISSN 0044-8249, 08/2016, Volume 128, Issue 34, p. 10128
  The C[delta]-H amination of unactivated, secondary C-H bonds to form a broad range of functionalized pyrrolidines has been developed by a triiodide... 
Journal Article
Organic Letters, ISSN 1523-7060, 10/2017, Volume 19, Issue 20, pp. 5693 - 5696
N-Alkyl substituted chlorotetrazines were coupled with various boronic acids under Suzuki conditions in high yield at room temperature, giving a mild and... 
POSITIVE ALLOSTERIC MODULATOR | DIELS-ALDER REACTIONS | CHEMISTRY | CHEMISTRY, ORGANIC | PYRIDAZINES | DISCOVERY | S-TETRAZINES
Journal Article
Angewandte Chemie, ISSN 0044-8249, 08/2016, Volume 128, Issue 34, pp. 10128 - 10132
The Cδ−H amination of unactivated, secondary C−H bonds to form a broad range of functionalized pyrrolidines has been developed by a triiodide (I3−)‐mediated... 
Radikalchemie | Wasserstoffatomtransfer | C-H-Funktionalisierung | Aminierungen | Triiodid | Utilities | Chemical bonds | Strategy | Decomposition | Nuclear magnetic resonance | Sodium iodides | Iodine
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 08/2019, Volume 29, Issue 16, pp. 2224 - 2228
This letter describes progress towards an M PAM preclinical candidate inspired by an unexpected aldehyde oxidase (AO) metabolite of a novel, CNS penetrant... 
Aldehyde oxidase (AO) | Structure-activity relationship (SAR) | Positive allosteric modulator (PAM) | Muscarinic acetylcholine receptor | M
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 08/2019, Volume 29, Issue 16, p. 2224
This letter describes progress towards an M.sub.4 PAM preclinical candidate inspired by an unexpected aldehyde oxidase (AO) metabolite of a novel, CNS... 
Oxidases | Medical colleges | Neurosciences | Pyridine | Metabolites | Lubrication and lubricants | Physiological aspects | Drug discovery | Aldehydes
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, ISSN 0960-894X, 08/2019, Volume 29, Issue 16, pp. 2224 - 2228
This letter describes progress towards an M-4 PAM preclinical candidate inspired by an unexpected aldehyde oxidase (AO) metabolite of a novel, CNS penetrant... 
Aldehyde oxidase (AO) | CHEMISTRY, MEDICINAL | SERIES | PRECLINICAL CANDIDATE | CHEMISTRY, ORGANIC | RECEPTOR | CHALLENGES | Muscarinic acetylcholine receptor | Structure-activity relationship (SAR) | VIVO TOOL COMPOUND | M-4 | Positive allosteric modulator (PAM) | POSITIVE ALLOSTERIC MODULATORS | OPTIMIZATION | POTENTIATORS
Journal Article
No results were found for your search.

Cannot display more than 1000 results, please narrow the terms of your search.