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Journal Article
PLoS ONE, ISSN 1932-6203, 02/2013, Volume 8, Issue 2, p. e57591
Enterovirus 71 (EV71) and coxsackievirus (CVA) are the most common causative factors for hand, foot, and mouth disease (HFMD) and neurological disorders in... 
VACCINE DEVELOPMENT | SELECTIN GLYCOPROTEIN LIGAND-1 | NEUROLOGICAL DISEASE | MOUTH-DISEASE | MULTIDISCIPLINARY SCIENCES | P-SELECTIN | CENTRAL-NERVOUS-SYSTEM | BRAIN-STEM ENCEPHALITIS | CYNOMOLGUS MONKEYS | CELL-CULTURE | CEREBROSPINAL-FLUID | Enterovirus A, Human - genetics | Humans | Cercopithecus aethiops | Hand, Foot and Mouth Disease - genetics | Lysosome-Associated Membrane Glycoproteins - immunology | Enterovirus - genetics | Enterovirus Infections - genetics | Enterovirus Infections - immunology | Vero Cells | Disease Models, Animal | Cells, Cultured | Enterovirus A, Human - immunology | Hand, Foot and Mouth Disease - immunology | Genotype | Mice, Transgenic | Up-Regulation - genetics | Inflammation - immunology | Receptors, Scavenger - immunology | Coxsackievirus Infections - genetics | Animals | Receptors, Scavenger - genetics | Up-Regulation - immunology | Enterovirus - immunology | Lysosome-Associated Membrane Glycoproteins - genetics | T-Lymphocytes - immunology | Mice | Coxsackievirus Infections - immunology | Medical research | Nervous system diseases | Analysis | Medicine, Experimental | Genetic engineering | Paralysis | Coxsackievirus infections | Cell culture | Neuropathology | Pathogenesis | Central nervous system | Clinical isolates | Nervous system | Lymphocytes T | Hand-foot-and-mouth disease | Infections | Vaccines | Recruitment | Interleukin 6 | Proteins | Hepatitis | Immunology | Lymphocytes | Transgenic animals | Rodents | Animal tissues | Children | Edema | Encephalitis | Immunization | Cytokines | Neutrophils | Transgenic mice | CCL3 protein | Glycoproteins | Inflammation | Tumor necrosis factor-α | Feet | Neurological diseases | Enteroviruses | Infectious diseases | CXCL10 protein | Ligands | Chemokines | Viral infections
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, p. e30507
Enterovirus (EV) 71 infection is known to cause hand-foot-and-mouth disease (HFMD) and in severe cases, induces neurological disorders culminating in fatality.... 
CLATHRIN-MEDIATED ENDOCYTOSIS | SELECTIN GLYCOPROTEIN LIGAND-1 | PUBLIC-HEALTH | MOUTH-DISEASE | ENTEROVIRUS 71 | BIOLOGY | CELLULAR RECEPTOR | P-SELECTIN | DEPENDENT ENDOCYTOSIS | NEUROGENIC PULMONARY-EDEMA | RESPIRATORY SYNCYTIAL VIRUS | NIH 3T3 Cells | Dynamins - metabolism | Immunoprecipitation | Humans | Cercopithecus aethiops | Enterovirus A, Human - growth & development | Virus Internalization | Cell Membrane - chemistry | Endocytosis | Enterovirus Infections - virology | Transfection | RNA Interference | Vero Cells | Receptors, Scavenger - metabolism | Lysosome-Associated Membrane Glycoproteins - metabolism | Capsid Proteins - metabolism | Dynamins - genetics | Clathrin - genetics | Cholesterol - metabolism | Blotting, Western | Clathrin - metabolism | Animals | Receptors, Scavenger - genetics | Cell Line, Tumor | Endosomes - chemistry | Lysosome-Associated Membrane Glycoproteins - genetics | Protein Binding | Mice | Mice, Inbred BALB C | Enterovirus A, Human - metabolism | Hydrogen-Ion Concentration | Infection | Medical research | Clathrin | Nervous system diseases | Viral proteins | Medicine, Experimental | Coxsackievirus infections | Medicine, Preventive | Preventive health services | Caveolae | Caveolin | Disorders | Acidification | Outbreaks | Viruses | Hand-foot-and-mouth disease | Infections | siRNA | Vaccines | pH effects | Cholesterol | Neurological diseases | Proteins | Dynamin | Fatalities | Foot-and-mouth disease | Disruption | Public health | Vero cells | Viral infections | pH
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0175586 - e0175586
Developing lung cancer in mouse models that display similarities of both phenotype and genotype will undoubtedly provide further and better insights into lung... 
JAAGSIEKTE SHEEP RETROVIRUS | EXPRESSION | CANCER | MULTIDISCIPLINARY SCIENCES | Immunohistochemistry | Thyroid Nuclear Factor 1 | Adenocarcinoma - pathology | Nuclear Proteins - analysis | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Epithelial-Mesenchymal Transition - genetics | Neoplasm Metastasis | Pulmonary Adenomatosis, Ovine - genetics | Adenocarcinoma - metabolism | Adenocarcinoma - genetics | Lung - metabolism | Disease Models, Animal | Jaagsiekte sheep retrovirus - genetics | Lung Neoplasms - genetics | Lung - pathology | Multidrug Resistance-Associated Proteins - analysis | Viral Envelope Proteins - genetics | Gene Expression Profiling - methods | Mice, Transgenic | Reverse Transcriptase Polymerase Chain Reaction | Phenotype | Animals | Sheep | Transcription Factors - analysis | Retroviruses | Lung cancer | Physiological aspects | Development and progression | Genetic aspects | Research | Risk factors | Adenocarcinoma | Intervention | Animal models | Mesenchyme | Genes | Viruses | Metastasis | Drug screening | Carcinogenesis | Metastases | Proteins | Genotype & phenotype | Carcinogens | Histopathology | Transgenic animals | Rodents | Age | Medical research | Antigens | Research & development--R&D | Tumor cells | Transgenic mice | Envelope protein | Surfactants | Gene expression | Womens health | Medical prognosis | Biomarkers | Laboratory animals | Tumors | Index Medicus | Research & development | R&D
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0136420
Epidemics and outbreaks caused by infections of several subgenotypes of EV71 and other serotypes of coxsackie A viruses have raised serious public health... 
IMMUNIZATION | INFECTIONS | NEUTRALIZING ANTIBODIES | MOUTH-DISEASE | MULTIDISCIPLINARY SCIENCES | MICE | COXSACKIEVIRUS A16 | SELECTION | STRAIN | HAND | FOOT | Humans | Cercopithecus aethiops | Lysosome-Associated Membrane Glycoproteins - immunology | Cytokines - genetics | Vero Cells | Viral Vaccines - biosynthesis | Rabbits | Gene Expression | Enterovirus A, Human - immunology | Mice, Transgenic | Chemokines - genetics | Cross Reactions | Receptors, Scavenger - immunology | Coxsackievirus Infections - prevention & control | Coxsackievirus Infections - genetics | Vaccines, Inactivated - immunology | Animals | Receptors, Scavenger - genetics | Bioreactors | Vaccines, Inactivated - biosynthesis | Lysosome-Associated Membrane Glycoproteins - genetics | Mice | Mice, Inbred BALB C | Virus Cultivation | Viral Vaccines - immunology | Coxsackievirus Infections - immunology | Antigens | Genetic engineering | Vaccines | Health aspects | Enzyme-linked immunosorbent assay | Public health | Epidemics | Cell culture | Sucrose | Agricultural biotechnology | Aluminum | Pathogenesis | Centrifugation | Central nervous system | Clinical trials | Outbreaks | Inflammatory response | Viruses | Genomes | Infections | Serum-free medium | Transgenic animals | Combined vaccines | Aluminum phosphate | Paralysis | Sugars | Medical research | Encephalitis | Immunization | Immunoglobulins | Effectiveness | Transgenic mice | Muscles | Squalene | Inflammation | Infectious diseases | Serotypes | Vero cells
Journal Article
Vaccine, ISSN 0264-410X, 2014, Volume 32, Issue 47, pp. 6177 - 6182
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, pp. e77133 - e77133
Although several factors participating in enterovirus 71 (EV71) entry and replication had been reported, the precise mechanisms associated with these events... 
CAPSID PROTEIN | HSP90 | SELECTIN GLYCOPROTEIN LIGAND-1 | MOUTH-DISEASE | GELDANAMYCIN | MULTIDISCIPLINARY SCIENCES | MOLECULAR CHAPERONE | CELLULAR RECEPTOR | CENTRAL-NERVOUS-SYSTEM | CYNOMOLGUS MONKEYS | INFECTION | Enterovirus A, Human - genetics | RNA, Small Interfering - genetics | Virion - pathogenicity | Humans | Cercopithecus aethiops | Virion - genetics | Molecular Targeted Therapy | Virus Internalization - drug effects | Enterovirus Infections - virology | Enterovirus Infections - genetics | Proteolysis | HSP90 Heat-Shock Proteins - genetics | Enterovirus A, Human - pathogenicity | Vero Cells | Enterovirus Infections - drug therapy | Virus Replication - drug effects | Capsid Proteins - metabolism | Gene Expression Regulation | Mice, Transgenic | Lactams, Macrocyclic - pharmacology | Virion - drug effects | Antibodies - pharmacology | Benzoquinones - pharmacology | Host-Pathogen Interactions | Animals | Capsid Proteins - antagonists & inhibitors | Enterovirus A, Human - drug effects | HSP90 Heat-Shock Proteins - antagonists & inhibitors | Cell Line, Tumor | HSP90 Heat-Shock Proteins - metabolism | Protein Binding | Mice | Proteasome Endopeptidase Complex - metabolism | Capsid Proteins - genetics | RNA, Small Interfering - metabolism | Physiological aspects | Heat shock proteins | Enteroviruses | Genetic aspects | Research | Genetic transcription | Cell culture | Hsp90 protein | Transcription | Toxicity | Pathogenesis | Rhabdomyosarcoma | Viruses | Infections | Geldanamycin | Vaccines | Cancer therapies | Degradation | Proteins | Transgenic animals | Virions | Biocompatibility | Inhibition | Genotypes | Recombinant | Heparan sulfate | Encephalitis | Medical research | Polypeptides | Transgenic mice | siRNA | Gene expression | Infectious diseases | Inhibitors | Cellular biology | Replication | In vivo methods and tests | Heat shock | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, p. e34834
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, p. e69858
Hand-foot-mouth diseases (HFMD) caused by enterovirus 71 (EV71) and coxsackievirus 16 (CVA16) in children have now become a severe public health issue in the... 
VIRUS | TAIWAN | INTRAVENOUS IMMUNOGLOBULIN | ENCEPHALITIS | MULTIDISCIPLINARY SCIENCES | CENTRAL-NERVOUS-SYSTEM | CYNOMOLGUS MONKEYS | CELL-CULTURE | LETHAL ENTEROVIRUS-71 INFECTION | NEWBORN MICE | CHILDREN | Enterovirus A, Human - genetics | Humans | Hand, Foot and Mouth Disease - genetics | Viral Load | Coxsackievirus Infections - virology | Antibodies, Neutralizing - immunology | Hand, Foot and Mouth Disease - prevention & control | Antibody Specificity - immunology | Inflammation Mediators - metabolism | Capsid Proteins - immunology | Antibodies, Monoclonal - immunology | Hand, Foot and Mouth Disease - virology | Cytokines - immunology | Disease Models, Animal | Inflammation Mediators - immunology | Gene Expression | Cytokines - metabolism | Enterovirus A, Human - immunology | Hand, Foot and Mouth Disease - immunology | Genotype | Mice, Transgenic | Cross Reactions - immunology | Coxsackievirus Infections - prevention & control | Animals | Receptors, Scavenger - genetics | Lysosome-Associated Membrane Glycoproteins - genetics | Antibodies, Viral - immunology | Mice | Hand, Foot and Mouth Disease - mortality | Coxsackievirus Infections - immunology | Capsid Proteins - genetics | Infection | Viral antibodies | Medical research | Cytokines | Analysis | Medicine, Experimental | Antibodies | Skin | Genetic engineering | Paralysis | Coxsackievirus infections | VP1 protein | Brain | Cell culture | Spinal cord | Pathogenesis | Viruses | Infections | Vaccines | Genotype & phenotype | Reduction | Immunology | Transgenic animals | Rodents | Children | Public health | Encephalitis | Edema | Immunoglobulins | Effectiveness | Transgenic mice | Muscles | Inflammation | Infectious diseases | Brain research | Neutralizing
Journal Article