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Journal Article
Biochemical journal, ISSN 0264-6021, 07/2009, Volume 421, Issue 1, pp. 29 - 42
mTOR (mammalian target of rapamycin) stimulates cell growth by phosphorylating and promoting activation of AGC (protein kinase A/protein kinase G/protein... 
Phosphoinositide 3-kinase (PI3K) | Akt/protein kinase B (PKB) | Serum and glucocorticoid protein kinase (SGK) | P70 ribosomal S6 kinase (S6K) | Kinase inhibitor | Cancer | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Cell Line | Humans | Multiprotein Complexes | Morpholines - pharmacology | Transcription Factors - antagonists & inhibitors | Gene Expression Profiling | G1 Phase - drug effects | Pyrimidines - pharmacology | Morpholines - chemistry | Pyrimidines - chemistry | Mechanistic Target of Rapamycin Complex 1 | Gene Expression Regulation - drug effects | Proteins | Transcription Factors - metabolism | Animals | Fibroblasts - drug effects | Cell Proliferation - drug effects | Mice | TOR Serine-Threonine Kinases | Fibroblasts - metabolism | Index Medicus | PI3K, phosphoinositide 3-kinase | PDK, 3-phosphoinositide-dependent protein kinase | AMPK, AMP-activated protein kinase | mTORC, mTOR complex | DTT, dithiothreitol | phosphoinositide 3-kinase (PI3K) | p70 ribosomal S6 kinase (S6K) | SPHK, sphingosine kinase | ERK, extracellular-signal-regulated kinase | RSK, ribosomal S6 kinase | PH domain, pleckstrin homology domain | protein kinase B (PKB) | protein kinase G | NDRG1, N-Myc downstream-regulated gene-1 | IGF, insulin-like growth factor | mTOR, mammalian target of rapamycin | GST, glutathione transferase | SGK, serum and glucocorticoid protein kinase | PKC, protein kinase C | S6K, p70 ribosomal S6 kinase | eIF4E, eukaryotic initiation factor 4E | 4E-BP1, eIF4E-binding protein 1 | protein kinase C family | Akt | PRAS40, proline-rich Akt substrate of 40 kDa | HEK-293 cell, human embryonic kidney 293 cell | kinase inhibitor | MEF, mouse embryonic fibroblast | AGC family, protein kinase A | cancer | serum and glucocorticoid protein kinase (SGK) | MAPK, mitogen-activated protein kinase
Journal Article
PloS one, ISSN 1932-6203, 09/2010, Volume 5, Issue 9, pp. e13026 - e13026
...Author(s): Jieru Meng 1,*, Bingliang Fang 1, Yong Liao 2, Christine M. Chresta 3, Paul D. Smith 3, Jack A. Roth 1 Introduction Activation of the Ras/Raf/MEK... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Lung Neoplasms - physiopathology | MAP Kinase Kinase 1 - genetics | Bcl-2-Like Protein 11 | Forkhead Transcription Factors - metabolism | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Gene Expression Regulation, Neoplastic - drug effects | MAP Kinase Kinase 2 - genetics | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | MAP Kinase Kinase 1 - antagonists & inhibitors | Lung Neoplasms - enzymology | Membrane Proteins - genetics | Enzyme Inhibitors - pharmacology | MAP Kinase Kinase 1 - metabolism | Proto-Oncogene Proteins - genetics | MAP Kinase Kinase 2 - metabolism | Down-Regulation - drug effects | Forkhead Transcription Factors - genetics | Apoptosis Regulatory Proteins - metabolism | MAP Kinase Kinase 2 - antagonists & inhibitors | Cell Line, Tumor | Benzimidazoles - pharmacology | Forkhead Box Protein O3 | Prevention | Proteins | Lung cancer | Cancer cells | Disease susceptibility | Cancer | Apoptosis | Cell proliferation | Biotechnology | Phosphorylation | Bcl-2 protein | Heart surgery | Leukemia | AKT protein | Biochemistry | Kinases | Cancer therapies | Subgroups | Transfection | Rodents | Cell cycle | Trends | Inhibition | Deoxyribonucleic acid--DNA | FOXO3 protein | Translocation | MEK inhibitors | Breast cancer | siRNA | Tumor cell lines | Nuclear transport | 1-Phosphatidylinositol 3-kinase | Chemotherapy | Cell death | Morphology | Prostate cancer | BIM protein | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 03/2010, Volume 70, Issue 6, pp. 2264 - 2273
Journal Article
Journal Article
Molecular cancer therapeutics, ISSN 1538-8514, 09/2015, Volume 14, Issue 11, pp. 2508 - 2518
Journal Article