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DIABETES, ISSN 0012-1797, 08/2013, Volume 62, Issue 8, pp. 2784 - 2795
We previously mapped a locus on BALB/c chromosome 2 associated with protection from leptin-deficiency-induced obesity. Here, we generated the corresponding... 
ADIPOSE TRIGLYCERIDE LIPASE | UBIQUITIN-CONJUGATING ENZYMES | LIPOLYSIS | INSULIN-RESISTANCE | IN-VIVO | TISSUE | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | PPAR-GAMMA | MICE | DIET-INDUCED OBESITY | Adipose tissues | Physiological aspects | Obesity | Genetic aspects | Gene mutations | Analysis
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2006, Volume 12, Issue 5, pp. 534 - 540
Journal Article
Journal Article
Diabetes, ISSN 0012-1797, 01/2013, Volume 62, Issue 1, p. 183
Type 2 diabetes involves insulin resistance and [beta]-cell failure leading to inadequate insulin secretion. An important component of [beta]-cell failure is... 
Type 2 diabetes | Physiological aspects | Pancreatic beta cells | Research | Endoplasmic reticulum | Apoptosis
Journal Article
Neuron, ISSN 0896-6273, 2004, Volume 42, Issue 6, pp. 983 - 991
Journal Article
PLoS Biology, ISSN 1544-9173, 04/2018, Volume 16, Issue 4, p. e2004399
Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARC) respond to numerous hormonal and neural signals, resulting in changes in... 
TRPV CHANNEL SUBUNITS | ALPHA-MSH | ENERGY HOMEOSTASIS | PAIN PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROOPIOMELANOCORTIN NEURONS | BIOLOGY | ION-CHANNEL | VANILLOID RECEPTOR | DIET-INDUCED OBESITY | LEPTIN RESISTANCE | EXPRESSION | Temperature | Capsaicin - pharmacology | Arcuate Nucleus of Hypothalamus - cytology | Male | Neurons - cytology | Optogenetics | Channelrhodopsins - metabolism | TRPV Cation Channels - deficiency | Arcuate Nucleus of Hypothalamus - drug effects | Receptors, Melanocortin - metabolism | Female | Neurons - metabolism | Neurons - drug effects | Pro-Opiomelanocortin - genetics | Single-Cell Analysis | Genes, Reporter | Physical Conditioning, Animal | Signal Transduction | Arcuate Nucleus of Hypothalamus - metabolism | TRPV Cation Channels - agonists | Bacterial Proteins - genetics | Gene Expression Regulation | Mice, Transgenic | Channelrhodopsins - genetics | Gene Knockout Techniques | Eating - genetics | Receptors, Melanocortin - genetics | TRPV Cation Channels - genetics | Gene Knock-In Techniques | Pro-Opiomelanocortin - metabolism | Eating - drug effects | Animals | Enhancer Elements, Genetic | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Mice | Luminescent Proteins - metabolism | Immunohistochemistry | Capsaicin | Arcuate nucleus | Fluorescence | Electrophysiology | Reverse transcription | Capsaicin receptors | Viruses | Proopiomelanocortin | Activation | Hypothalamus | Proteins | Depolarization | Transient receptor potential proteins | Receptors | Elevation | Temperature effects | Rodents | Physiology | Food | Appetite | CRISPR | Yellow fluorescent protein | Neurons | Fitness equipment | Body temperature | Melanocortin | Gene expression | Medicine | Polymerase chain reaction | Enhancers | Weight control | Food intake | Running | Data collection | Endocrinology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2005, Volume 115, Issue 12, pp. 3484 - 3493
Journal Article
Journal Article
Journal Article
Neuron, ISSN 0896-6273, 2005, Volume 48, Issue 6, pp. 1055 - 1066
Recently developed therapeutics for obesity, targeted against cannabinoid receptors, result in decreased appetite and sustained weight loss. Prior studies have... 
HYPOTHALAMIC CONTROL | ENERGY-BALANCE | ENDOGENOUS CANNABINOIDS | IN-VITRO | FOOD-INTAKE | LONG-TERM DEPRESSION | RAT HYPOTHALAMUS | CB1 CANNABINOID RECEPTOR | METABOTROPIC GLUTAMATE | REPORTER GENE | NEUROSCIENCES | Cannabinoid Receptor Modulators - metabolism | Cannabinoid Receptor Modulators - pharmacology | Hypothalamic Area, Lateral - metabolism | MAP Kinase Signaling System - physiology | Neural Pathways - drug effects | Calcium Channels - metabolism | Protein-Tyrosine Kinases - metabolism | Leptin - metabolism | Janus Kinase 2 | Neural Inhibition - physiology | Motivation | Time Factors | Leptin - pharmacology | Neurons - metabolism | Hypothalamus - drug effects | Neurons - drug effects | Endocannabinoids | Organ Culture Techniques | Calcium Channels - drug effects | Membrane Potentials - drug effects | Proto-Oncogene Proteins - metabolism | Receptors, Leptin | Hypothalamus - physiology | Mice, Inbred C57BL | Appetite Regulation - drug effects | Mice, Transgenic | Leptin - genetics | Membrane Potentials - physiology | Receptor, Cannabinoid, CB1 - metabolism | Patch-Clamp Techniques | Animals | MAP Kinase Signaling System - drug effects | Signal Transduction - drug effects | Calcium Signaling - drug effects | Hypothalamic Area, Lateral - drug effects | Neural Pathways - metabolism | Signal Transduction - physiology | Mice | Appetite Regulation - physiology | Receptor, Cannabinoid, CB1 - antagonists & inhibitors | Reward | Calcium Signaling - genetics | Neural Inhibition - drug effects | Calcium channels | Peptide hormones | Neurons | Protein kinases | Leptin | Medical societies | Studies | Hypotheses | Kinases | Rodents | Food
Journal Article