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Journal of Educational Technology & Society, ISSN 1176-3647, 7/2013, Volume 16, Issue 3, pp. 102 - 118
This study examined whether or not on-line learning (on-line as compared to classroom) influenced the progression of scientific concept construction and... 
Learning | Statistical significance | Analogies | Science education | Electronic learning | Deductive reasoning | Perceptual similarity | Reasoning | Science learning | Full Length Articles | Educational environment
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. 5424 - 5424
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 7/2012, Volume 134, Issue 2, pp. 649 - 659
Despite recent advances in the clinical evaluation of various poly(ADP-ribose) polymerase (PARP) inhibitors in triple-negative breast cancer (TNBC) patients,... 
Poly(ADP-ribose) polymerase | Oncology | Medicine & Public Health | PARP inhibitors | Triple-negative breast cancer | PATHWAYS | CHEMOSENSITIVITY | APOPTOSIS | ACTIVATION | 4-IODO-3-NITROBENZAMIDE | MUTANT-CELLS | COMBINATION | TUMORS | ONCOLOGY | ROLES | AZD2281 | Receptors, Estrogen - metabolism | Humans | Phosphoprotein Phosphatases - metabolism | Receptor, ErbB-2 - metabolism | Cell Line, Tumor - drug effects | Tumor Suppressor Protein p53 - genetics | Gene Knockdown Techniques | Receptors, Progesterone - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | RNA Interference | BRCA1 Protein - metabolism | Inhibitory Concentration 50 | Female | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Nuclear Proteins - genetics | Cell Survival - drug effects | Signal Transduction | Tumor Suppressor Protein p53 - metabolism | Nuclear Proteins - metabolism | Cisplatin - pharmacology | Down-Regulation - drug effects | Breast Neoplasms - drug therapy | Piperazines - pharmacology | Poly(ADP-ribose) Polymerase Inhibitors | Drug Synergism | BRCA1 Protein - genetics | Phthalazines - pharmacology | Poly(ADP-ribose) Polymerases - metabolism | Phosphoprotein Phosphatases - genetics | Benzimidazoles - pharmacology | Cell Proliferation - drug effects | Poly (ADP-Ribose) Polymerase-1 | Breast cancer | Analysis | Sugars | Monosaccharides
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 05/2014, Volume 20, Issue 15, pp. 2607 - 2618
Adenosine monophosphate-activated protein kinase (AMPK) is a key player in maintaining energy homeostasis in response to metabolic stress. Beyond diabetes and... 
Journal Article
Current pharmaceutical design, 2014, Volume 20, Issue 15, p. 2607
Adenosine monophosphate-activated protein kinase (AMPK) is a key player in maintaining energy homeostasis in response to metabolic stress. Beyond diabetes and... 
AMP-Activated Protein Kinases - physiology | Phosphorylation | Animals | Protein Kinase Inhibitors - therapeutic use | AMP-Activated Protein Kinases - antagonists & inhibitors | Humans | Gene Expression Regulation | Enzyme Activation | Histone Deacetylases - physiology | Autophagy | Neoplasms - drug therapy
Journal Article
British Journal of Ophthalmology, ISSN 0007-1161, 05/2019, Volume 103, Issue 5, pp. 666 - 671
AimTo determine the prevalence and clinical consequences of cytomegalovirus (CMV) DNA in the aqueous and corneal tissues obtained at the time of corneal... 
Infection | Cornea | Aqueous humour | Diagnostic tests/Investigation | ANTERIOR-CHAMBER | HERPES-SIMPLEX-VIRUS | ENDOTHELIITIS | PENETRATING KERATOPLASTY | OPHTHALMOLOGY | PATIENT | FEATURES
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 52, pp. 43639 - 43650
Journal Article
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 07/2012, Volume 134, Issue 2, p. 649
Journal Article
Current Pharmaceutical Design, ISSN 1381-6128, 2014, Volume 20, Issue 15, pp. 2607 - 2618
Adenosine monophosphate-activated protein kinase (AMPK) is a key player in maintaining energy homeostasis in response to metabolic stress. Beyond diabetes and... 
Metabolic homeostasis | Cancer therapy | AMPK | Foxo3a | HIF-1α | LKB1 | mTORC1 | HDAC | metabolic homeostasis | TRANSCRIPTIONAL ACTIVITY | HIF-1 alpha | ACTIVATED PROTEIN-KINASE | CELL-GROWTH | DIRECT PHOSPHORYLATION | LKB1-AMPK PATHWAY | cancer therapy | SKELETAL-MUSCLE | ENERGY-SENSOR | DOUBLE-EDGED-SWORD | PROSTATE-CANCER | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47298
Substantial evidence supports the oncogenic role of the E3 ubiquitin ligase S-phase kinase-associated protein 2 (Skp2) in many types of cancers through its... 
ANAPHASE-PROMOTING COMPLEX | DESTRUCTION | PROTEIN | UBIQUITIN LIGASE | BETA-TRCP | COP9 SIGNALOSOME | MULTIDISCIPLINARY SCIENCES | DEGRADATION | SCFSKP2 | PHOSPHORYLATION-DEPENDENT PROTEOLYSIS | CYCLE | Sirtuin 1 - metabolism | Prostatic Neoplasms - metabolism | S-Phase Kinase-Associated Proteins - physiology | Peptide Hydrolases - genetics | Humans | Gene Expression Regulation, Neoplastic | Male | Multiprotein Complexes - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Breast Neoplasms - metabolism | Multiprotein Complexes - metabolism | Breast Neoplasms - enzymology | beta-Transducin Repeat-Containing Proteins - metabolism | Female | Binding Sites | Intracellular Signaling Peptides and Proteins - genetics | Peptide Hydrolases - metabolism | Mutagenesis, Site-Directed | COP9 Signalosome Complex | S-Phase Kinase-Associated Proteins - metabolism | beta-Transducin Repeat-Containing Proteins - chemistry | Feedback, Physiological | Energy Metabolism | Sirtuin 1 - physiology | Cell Line, Tumor | Prostatic Neoplasms - enzymology | S-Phase Kinase-Associated Proteins - genetics | Ligases | Cancer cells | Physiological aspects | Genetic aspects | Research | Properties | Prostate cancer | Risk factors | Ubiquitin | Phosphorylation | Crosstalk | Transducin | Proline | Feedback loops | Glucose | Kinases | Accumulation | Deoxyglucose | Cullin | Proteins | Cyclin-dependent kinase | Ubiquitination | Energy | Feedback | Cell cycle | Pharmaceutical sciences | Ubiquitin-protein ligase | Medical research | Enzymes | F-box protein | Breast cancer | Gene expression | Sp1 protein | SIRT1 protein | Substrates | Cyclin-dependent kinase 2 | Signaling | Skp2 protein | Skp2 gene | Medical prognosis | Pharmacy | Aberration | Drug discovery | Destabilization | Prostate | Cancer
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 8 Supplement, pp. 1360 - 1360
Journal Article
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e0202299
Although the rictor-mTOR complex (mTORC2) has been shown to act as phosphoinositide-dependent kinase (PDK) 2 in many cell types, other kinases have also been... 
EPITHELIAL-MESENCHYMAL TRANSITION | B/AKT ACTIVATION | AKT PHOSPHORYLATION | TUMOR PROGRESSION | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | THERAPEUTIC TARGET | EXPRESSION INCREASES | ILK | E-CADHERIN | INHIBITOR QLT0267 | Prostatic Neoplasms - metabolism | Up-Regulation | TOR Serine-Threonine Kinases - metabolism | Humans | Epithelial-Mesenchymal Transition - drug effects | Male | Mechanistic Target of Rapamycin Complex 2 | Breast Neoplasms - metabolism | Multiprotein Complexes - metabolism | Female | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Protein-Serine-Threonine Kinases - metabolism | Rapamycin-Insensitive Companion of mTOR Protein | Cell Survival - drug effects | PTEN Phosphohydrolase - deficiency | Protein-Serine-Threonine Kinases - genetics | Morpholines - pharmacology | Pyrimidines - pharmacology | Serine - metabolism | Carrier Proteins - genetics | Carrier Proteins - metabolism | Anilides - pharmacology | Benzoates - pharmacology | Cell Line, Tumor | Breast cancer | Epidermal growth factor | Phosphotransferases | Analysis | Integrins | TOR protein | Phosphorylation | Immunoprecipitation | Mesenchyme | Laboratories | AKT protein | Metastasis | Kinases | Autophagy | Metastases | Proteins | Cell growth | Bacteria | Inhibition | Pharmaceutical sciences | Deoxyribonucleic acid--DNA | ILK protein | siRNA | Tumor cell lines | Inhibitors | Pharmacy | Cell lines | Prostate | Prostate cancer | PTEN protein | Cancer | Deoxyribonucleic acid | DNA
Journal Article
Ophthalmology, ISSN 0161-6420, 2012, Volume 119, Issue 3, pp. 522 - 527
Journal Article