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Nature Chemistry, ISSN 1755-4330, 02/2016, Volume 8, Issue 2, pp. 114 - 119
Antibody-drug conjugates (ADCs) comprise antibodies covalently attached to highly potent drugs using a variety of conjugation technologies. As therapeutics,... 
Antibody Specificity | Immunoconjugates - chemistry | Humans | Antibodies, Monoclonal - chemistry | Drug Design | Pharmaceutical Preparations - chemistry
Journal Article
Drug Discovery Today: Technologies, ISSN 1740-6749, 12/2018, Volume 30, pp. 1 - 2
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 79, pp. 11180 - 11183
Journal Article
ISSN 1359-7345, 10/2018, Volume 54, Issue 79, pp. 1118 - 11183
Herein we report the transformation of readily synthesised acyl hydrazides into 2-hydrazobenzophenones via a novel molecular rearrangement pathway using aryne... 
Journal Article
Chemical Communications : Chem Comm, ISSN 1359-7345, 01/2018, Volume 54, Issue 79, pp. 11180 - 11183
Herein we report the transformation of readily synthesised acyl hydrazides into 2-hydrazobenzophenones via a novel molecular rearrangement pathway using aryne... 
Organic chemistry | Nuclear magnetic resonance--NMR | Hydrazides | Iridium | Chemical synthesis | Functional groups
Journal Article
Chemical Science, ISSN 2041-6520, 1/2018, Volume 9, Issue 4, pp. 79 - 81
The folate receptor (FR) is a recognised biomarker for tumour cells due to its overexpression on a large number of tumours. Consequently, the FR has been... 
Conjugates | Imaging | Vitamin B | Diagnostic software | Biomarkers | Antibodies | Diagnostic systems | Nanotechnology
Journal Article
Organic & Biomolecular Chemistry, ISSN 1477-0520, 01/2019, Volume 17, Issue 11, pp. 2865 - 2872
Herein we describe recent developments in selective, metal-free, dioxygen-induced C–H activation. This method of activating C–H bonds is an attractive... 
Metals | Activation | Peroxides | Index Medicus
Journal Article
RSC Advances, ISSN 2046-2069, 2015, Volume 5, Issue 55, pp. 44423 - 44426
The unique properties of pentafluorophenyl vinyl sulfonate allow for a hitherto unmet feat to be realised; efficient and high yielding, metal-free,... 
N-HYDROXYPHTHALIMIDE NHPI | ESTERS | POLARITY-REVERSAL CATALYST | C-H ACTIVATION | CIS,CIS-1,5-CYCLOOCTADIENE | CYCLOPROPENES | CHEMISTRY, MULTIDISCIPLINARY | Sulfonates | Aldehydes | Olefins | Constraining
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 01/2020
Herein we report the synthesis of a library of thioalkyl- and thioaryl-pyridazinediones for thiol-based self-immolative release of cargo. A... 
Journal Article
Nature Chemistry, ISSN 1755-4330, 07/2010, Volume 2, Issue 7, pp. 592 - 596
The development of methods for carbon-carbon bond formation under benign conditions is an ongoing challenge for the synthetic chemist. In recent years there... 
ORGANIC-SYNTHESIS | ALKENES | BENZALDEHYDE | COMPLEXES | CHEMISTRY | N-HYDROXYPHTHALIMIDE | ALDEHYDES | RADICALS | CHEMISTRY, MULTIDISCIPLINARY | EPOXIDATION | MOLECULAR-OXYGEN | Alkenes - chemistry | Oxidation-Reduction | Ketones - chemistry | Esters | Catalysis | Carbon - chemistry | Acylation | Aldehydes - chemistry | Organic chemistry | Catalysts | Ketones | Reagents | Chemical bonds | Activation | Oxidation | Aldehydes | Carbon | Bonding | Intermediates
Journal Article
RSC Advances, ISSN 2046-2069, 2015, Volume 5, Issue 55, pp. 44423 - 44426
The unique properties of pentafluorophenyl vinyl sulfonate allow for a hitherto unmet feat to be realised; efficient and high yielding, metal-free,... 
Journal Article
Chemical Science, ISSN 2041-6520, 12/2016, Volume 8, Issue 1, pp. 63 - 77
Recent advances in nanomedicine have shown that dramatic improvements in nanoparticle therapeutics and diagnostics can be achieved through the use of disease... 
Nanoparticles | Conjugates | Switches | Antibodies | Fragments | Ligands | Diagnostic systems | Nanostructure
Journal Article
Chemical Science, ISSN 2041-6520, 12/2016, Volume 8, Issue 1, pp. 63 - 77
Recent advances in nanomedicine have shown that dramatic improvements in nanoparticle therapeutics and diagnostics can be achieved through the use of disease... 
IRON-OXIDE NANOPARTICLES | BREAST-CANCER | IN-VITRO | DRUG-DELIVERY | MESOPOROUS SILICA NANOPARTICLES | BLOCK-COPOLYMER MICELLES | SINGLE-DOMAIN ANTIBODIES | MAGNETIC NANOPARTICLES | CHEMISTRY, MULTIDISCIPLINARY | CARBON NANOTUBES | QUANTUM DOTS | Chemistry
Journal Article
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 10/2018, Volume 54, Issue 79, pp. 11180 - 11183
Herein we report the transformation of readily synthesised acyl hydrazides into 2-hydrazobenzophenones via a novel molecular rearrangement pathway using aryne... 
PRODUCTS THEREOF | MILD CONDITIONS | COUPLING REACTIONS | CONVERSION | INDAZOLES | CHEMISTRY | ALDEHYDES | INHIBITORS | CHEMISTRY, MULTIDISCIPLINARY | METAL-FREE | HYDROACYLATION
Journal Article
05/2015, Volume 5, Issue 55, pp. 44423 - 44426
The unique properties of pentafluorophenyl vinyl sulfonate allow for a hitherto unmet feat to be realised; efficient and high yielding, metal-free,... 
Journal Article
Organic and Biomolecular Chemistry, ISSN 1477-0520, 3/2019, Volume 17, Issue 11, pp. 2865 - 2872
Herein we describe recent developments in selective, metal-free, dioxygen-induced C-H activation. This method of activating C-H bonds is an attractive... 
OXIDATION | FUNCTIONALIZATION | DIETHYL-ETHER | CONVERSION | CHEMISTRY, ORGANIC | ACYL HYDRAZIDES | BOND ACTIVATION | ALDEHYDES | FACILE | EFFICIENT | HYDROACYLATION
Journal Article
Nature chemistry, ISSN 1755-4330, 03/2016, Volume 8, Issue 3, p. 281
Journal Article
Drug Discovery Today: Technologies, ISSN 1740-6749, 12/2018, Volume 30, pp. 27 - 34
Bioconjugation, the modification of biological macromolecules such as proteins, is an up and coming area in the field of chemical biology. Antibody-drug... 
Viral antibodies | Proteins | Biological products | Chemical tests and reagents | Therapeutics | Antibodies | Homeopathy | Materia medica and therapeutics
Journal Article
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