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AIP Conference Proceedings, ISSN 0094-243X, 05/2016, Volume 1728, Issue 1
Journal Article
Cancer Letters, ISSN 0304-3835, 2014, Volume 348, Issue 1, pp. 156 - 166
Abstract The tumor necrosis factor related apoptosis-inducing ligand (TRAIL) causes cancer cell death, but many cancers, including pancreatic cancer, are... 
Hematology, Oncology and Palliative Medicine | TRAIL | Pancreatic cancer | Triptolide | Death receptor | Apoptosis | MOMP | LMP | HEAT-SHOCK-PROTEIN-70 | INDUCED APOPTOSIS | MITOCHONDRIAL | RELEASE | CYTOCHROME-C | CATHEPSINS | ONCOLOGY | BAX | LIGAND | PROTEINS | MEMBRANE PERMEABILIZATION | Pancreatic Neoplasms - metabolism | Apoptosis - drug effects | Receptors, TNF-Related Apoptosis-Inducing Ligand - agonists | Humans | Caspase 8 - metabolism | Antineoplastic Agents, Alkylating - pharmacology | Receptors, TNF-Related Apoptosis-Inducing Ligand - metabolism | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Caspase 8 - genetics | Mitochondrial Membranes - drug effects | Epoxy Compounds - pharmacology | Lysosomes - metabolism | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Transfection | RNA Interference | Receptors, TNF-Related Apoptosis-Inducing Ligand - genetics | CASP8 and FADD-Like Apoptosis Regulating Protein - metabolism | BH3 Interacting Domain Death Agonist Protein - metabolism | Diterpenes - pharmacology | Lysosomes - drug effects | Cell Survival - drug effects | CASP8 and FADD-Like Apoptosis Regulating Protein - genetics | Pancreatic Neoplasms - pathology | bcl-2-Associated X Protein - metabolism | Pancreatic Neoplasms - genetics | Permeability | Mitochondrial Membranes - metabolism | Phenanthrenes - pharmacology | Animals | Signal Transduction - drug effects | Cell Line, Tumor | Mice | Enzyme Activation | Drug Resistance, Neoplasm - drug effects | Studies | Cell culture | Pancreas | Binding sites | Index Medicus | triptolide | apoptosis | pancreatic cancer | death receptor
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 06/2011, Volume 300, Issue 6, pp. 948 - 955
Journal Article
Surgery: Official Journal of the Society of University Surgeons, Central Surgical Association, and the American Association of Endocrine Surgeons, ISSN 0039-6060, 2014, Volume 156, Issue 2, pp. 270 - 279
Introduction Sorafenib is the only drug approved by the Food and Drug Administration for metastatic hepatocellular carcinoma (HCC). Triptolide, a diterpene... 
Surgery | SURGERY | APOPTOSIS | HEAT-SHOCK-PROTEIN-70 | INHIBITION | GROWTH | MOLECULAR TARGETED THERAPIES | PROLIFERATION | NF-KAPPA-B | CANCER | RAF/MEK/ERK PATHWAY | CELL-DEATH | Caspase 7 - metabolism | Niacinamide - analogs & derivatives | Prodrugs - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Sincalide - metabolism | Liver Neoplasms, Experimental - metabolism | Carcinoma, Hepatocellular - drug therapy | Diterpenes - administration & dosage | Epoxy Compounds - administration & dosage | Liver Neoplasms - pathology | Liver Neoplasms, Experimental - pathology | Organophosphates - administration & dosage | Cell Survival - drug effects | NF-kappa B p50 Subunit - metabolism | Translational Medical Research | Liver Neoplasms - drug therapy | Phenanthrenes - administration & dosage | Niacinamide - administration & dosage | Drug Synergism | Xenograft Model Antitumor Assays | Animals | Liver Neoplasms, Experimental - drug therapy | Phenylurea Compounds - administration & dosage | Signal Transduction - drug effects | Mice, Nude | Models, Biological | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Mice | Carcinoma, Hepatocellular - metabolism | Antimitotic agents | Care and treatment | Hepatoma | Antineoplastic agents | Drug approval | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2019, Volume 294, Issue 27, pp. 10739 - 10739
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 06/2014, Volume 306, Issue 11, pp. G1011 - G1020
Pancreatic cancer is a devastating disease with a survival rate of <5%. Moreover, pancreatic cancer aggressiveness is closely related to high levels of... 
Glucose-regulated protein 78 | Autophagy | Pancreatic cancer | Triptolide | Apoptosis | Endoplasmic reticulum stress | DEATH PROGRAM | PHYSIOLOGY | autophagy | glucose-regulated protein 78 | INDUCED APOPTOSIS | GRP78 | apoptosis | triptolide | ENDOPLASMIC-RETICULUM STRESS | endoplasmic reticulum stress | NEGATIVE REGULATOR | BREAST-CANCER | COLON-CANCER | pancreatic cancer | HEPATOCELLULAR-CARCINOMA | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | Pancreatic Neoplasms - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Gene Knockdown Techniques | DNA-Binding Proteins - metabolism | Heat-Shock Proteins - genetics | Epoxy Compounds - pharmacology | Endoplasmic Reticulum - drug effects | Apoptosis Regulatory Proteins - genetics | Membrane Proteins - metabolism | Stress, Physiological - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Beclin-1 | Diterpenes - pharmacology | Unfolded Protein Response - drug effects | Membrane Proteins - genetics | Down-Regulation | Heat-Shock Proteins - metabolism | Endoplasmic Reticulum - physiology | Gene Silencing | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Regulatory Factor X Transcription Factors | Apoptosis Regulatory Proteins - metabolism | Transcription Factors - metabolism | Phenanthrenes - pharmacology | Animals | Cell Line, Tumor | Chronic Disease | Protein folding | Oncology, Experimental | Cancer cells | Physiological aspects | Research | Endoplasmic reticulum | Health aspects | Cancer | Enzymes | Survivor | Oncology | Stress response | Index Medicus | Cancer Biology
Journal Article
Journal of Urology, The, ISSN 0022-5347, 2016, Volume 195, Issue 4, pp. e1171 - e1172
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 10, pp. 8313 - 8322
CD133 has been implicated as a cancer stem cell (CSC) surface marker in several malignancies including pancreatic cancer. However, the functional role of this... 
NF-κB | Metastasis | Pancreatic Cancer | Invasion | CD133 | Index Medicus
Journal Article
AIP Conference Proceedings, ISSN 0094-243X, 05/2016, Volume 1728, Issue 1
Journal Article
Journal of Urology, The, ISSN 0022-5347, 2017, Volume 197, Issue 4, pp. e683 - e683
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2013, Volume 288, Issue 47, pp. 33927 - 33938
Pancreatic cancer, the fourth most prevalent cancer-related cause of death in the United States, is a disease with a dismal survival rate of 5% 5 years after... 
PATHWAYS | APOPTOSIS | ACTIVATION | ADENOCARCINOMA | BIOCHEMISTRY & MOLECULAR BIOLOGY | Pancreatic Cancer | KAPPA-B | O-GlcNAc | N-ACETYLGLUCOSAMINE TRANSFERASE | Heat Shock Protein | Minnelide | IN-VITRO | INHIBITION | Sp1 | Triptolide | Pancreas | TUMOR-GROWTH | EXPRESSION | Pancreatic Neoplasms - metabolism | Humans | Cell Survival - genetics | N-Acetylglucosaminyltransferases - genetics | Antineoplastic Agents, Alkylating - pharmacology | NF-kappa B - metabolism | Sp1 Transcription Factor - metabolism | Glycosylation - drug effects | Neoplasm Proteins - metabolism | Acetylglucosamine - metabolism | Heat Shock Transcription Factors | DNA-Binding Proteins - metabolism | Pancreatic Neoplasms - drug therapy | Cell Nucleus - metabolism | Epoxy Compounds - pharmacology | Cell Death - genetics | Cell Nucleus - pathology | Cell Death - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Active Transport, Cell Nucleus - genetics | Gene Expression Regulation, Neoplastic - genetics | HSP70 Heat-Shock Proteins - biosynthesis | Diterpenes - pharmacology | Cell Survival - drug effects | Pancreatic Neoplasms - pathology | HSP70 Heat-Shock Proteins - genetics | Pancreatic Neoplasms - genetics | Signal Transduction - genetics | Transcription Factors - genetics | Acetylglucosamine - genetics | DNA-Binding Proteins - genetics | Down-Regulation - drug effects | Down-Regulation - genetics | N-Acetylglucosaminyltransferases - metabolism | Transcription Factors - metabolism | Phenanthrenes - pharmacology | Cell Nucleus - genetics | NF-kappa B - genetics | Signal Transduction - drug effects | Sp1 Transcription Factor - genetics | Active Transport, Cell Nucleus - drug effects | Cell Line, Tumor | N-Acetylglucosaminyltransferases - antagonists & inhibitors | Index Medicus | Molecular Bases of Disease
Journal Article
The Prostate, ISSN 0270-4137, 05/2017, Volume 77, Issue 6, pp. 584 - 596
Journal Article
Journal Article
Journal of Urology, The, ISSN 0022-5347, 2016, Volume 195, Issue 4, pp. e332 - e332
Journal Article
Cancer Research, ISSN 0008-5472, 07/2015, Volume 75, Issue 13 Supplement, pp. A24 - A24
Journal Article
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