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1. Full Text Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
by Nation, Daniel A and Sweeney, Melanie D and Montagne, Axel and Sagare, Abhay P and D’Orazio, Lina M and Pachicano, Maricarmen and Sepehrband, Farshid and Nelson, Amy R and Buennagel, David P and Harrington, Michael G and Benzinger, Tammie L. S and Fagan, Anne M and Ringman, John M and Schneider, Lon S and Morris, John C and Chui, Helena C and Law, Meng and Toga, Arthur W and Zlokovic, Berislav V
Nature Medicine, ISSN 1078-8956, 02/2019, Volume 25, Issue 2, pp. 270 - 276
Vascular contributions to cognitive impairment are increasingly recognized1-5 as shown by neuropathological(6,7), neuroimaging(4,8-11), and cerebrospinal fluid... 
MEDICINE, RESEARCH & EXPERIMENTAL | VASCULAR RISK-FACTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | TAU | CEREBROSPINAL-FLUID | VESSEL DISEASE | CEREBROVASCULAR-DISEASE | CELL BIOLOGY | HUMAN CEREBRAL-CORTEX | NEUROVASCULAR DYSFUNCTION | EARLY ALZHEIMERS-DISEASE | FACTOR RECEPTOR-BETA | PERICYTES | Neuroimaging | Care and treatment | Usage | Research | Hippocampus (Brain) | Biological markers | Alzheimer's disease | Risk factors | Brain | Platelet-derived growth factor | Abnormalities | Magnetic resonance | Cognitive ability | Membrane permeability | Blood vessels | Cerebrospinal fluid | Permeability | Blood | Magnetic resonance imaging | Blood-brain barrier | Tau protein | Magnetic permeability | Vasoactive agents | Breakdown | Biomarkers | Brain damage | Amyloid | Bioindicators | Growth factors | Brain injury | Index Medicus
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2. Full Text Vascular risk and Ab interact to reduce cortical thickness in AD vulnerable brain regions
by Villeneuve, Sylvia and Reed, Bruce R and Madison, Cindee M and Wirth, Miranka and Marchant, Natalie L and Kriger, Stephen and Mack, Wendy J and Sanossian, Nerses and DeCarli, Charles and Chui, Helena C and Weiner, Michael W and Jagust, William J
Neurology, ISSN 0028-3878, 07/2014, Volume 83, Issue 1, pp. 40 - 47
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3. Full Text Abstract 183: Association of LDL Particles With Cerebral Amyloidosis
by Parekh, Trusha and King, Sarah M and Reed, Bruce and Chui, Helena C and Krauss, Ronald M and Yassine, Hussein
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2018, Volume 38, Issue Suppl_1
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4. Full Text PSYCHOMETRIC CHARACTERISTICS OF COGNITIVE RESERVE
by Rodriguez, Francisca S and Zheng, Ling and Chui, Helena C
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P584 - P585
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5. Full Text PYRAMIDAL SIGNS IN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE
by Ringman, John M and Sweeney, Melanie D and Zlokovic, Berislav and Chui, Helena C
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1183 - P1183
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6. Full Text A randomized controlled comparison of upper-extremity rehabilitation strategies in acute stroke: a pilot study of immediate and long-term outcomes
by Winstein, Carolee J and Rose, Dorian K and Tan, Sylvia M and Lewthwaite, Rebecca and Chui, Helena C and Azen, Stanley P
Archives of Physical Medicine and Rehabilitation, ISSN 0003-9993, 2004, Volume 85, Issue 4, pp. 620 - 628
Winstein CJ, Rose DK, Tan SM, Lewthwaite R, Chui HC, Azen SP. A randomized controlled comparison of upper-extremity rehabilitation strategies in acute stroke:... 
Stroke | Rehabilitation | Upper extremity | Disability evaluation | Randomized controlled trials | ARM IMPAIRMENT | SPORT SCIENCES | PHYSIOTHERAPY | PERFORMANCE | INTENSITY | STRENGTH | randomized controlled trials | disability evaluation | stroke | LEG | TRIAL | rehabilitation | THERAPY | MOTOR RECOVERY | upper extremity | Pilot Projects | Humans | Middle Aged | Physical Therapy Modalities | Stroke Rehabilitation | Adult | Treatment Outcome | Aged | Task Performance and Analysis | Index Medicus | Abridged Index Medicus
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7. Full Text The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer's disease
by Yassine, Hussein N and Rawat, Varun and Mack, Wendy J and Quinn, Joseph F and Yurko-Mauro, Karin and Bailey-Hall, Eileen and Aisen, Paul S and Chui, Helena C and Schneider, Lon S
Alzheimer's Research and Therapy, ISSN 1758-9193, 06/2016, Volume 8, Issue 1, pp. 25 - 25
Background: Apolipoprotein E (APOE) epsilon 4 and low cerebrospinal fluid (CSF) amyloid-beta 42 (A beta 42) levels are predictors for developing Alzheimer's... 
Amyloid | APOE | Cerebrospinal fluid | Alzheimer's disease | PHOSPHOLIPASE A | MILD COGNITIVE IMPAIRMENT | APOLIPOPROTEIN-E GENOTYPE | NEUROSCIENCES | CLINICAL NEUROLOGY | TRIAL | METABOLISM | DOCOSAHEXAENOIC ACID | POLYUNSATURATED FATTY-ACIDS | FISH-OIL | BRAIN | CONSUMPTION | Phosphorylation | Apolipoprotein E4 - genetics | Peptide Fragments - cerebrospinal fluid | Double-Blind Method | Follow-Up Studies | Humans | Genotype | tau Proteins - cerebrospinal fluid | Biomarkers - blood | Alzheimer Disease - cerebrospinal fluid | Docosahexaenoic Acids - administration & dosage | Amyloid beta-Peptides - blood | tau Proteins - blood | Alzheimer Disease - diet therapy | Docosahexaenoic Acids - blood | Docosahexaenoic Acids - cerebrospinal fluid | Peptide Fragments - blood | Amyloid beta-Peptides - cerebrospinal fluid | Biomarkers - cerebrospinal fluid | Alzheimer Disease - genetics | Dietary Supplements | Alzheimer Disease - blood | Physiological aspects | Genetic aspects | Research | Apolipoproteins | Risk factors | Index Medicus
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8. Full Text Blood-Brain Barrier Breakdown in the Aging Human Hippocampus
by Montagne, Axel and Barnes, Samuel R and Sweeney, Melanie D and Halliday, Matthew R and Sagare, Abhay P and Zhao, Zhen and Toga, Arthur W and Jacobs, Russell E and Liu, Collin Y and Amezcua, Lilyana and Harrington, Michael G and Chui, Helena C and Law, Meng and Zlokovic, Berislav V
Neuron, ISSN 0896-6273, 01/2015, Volume 85, Issue 2, pp. 296 - 302
The blood-brain barrier (BBB) limits entry of blood-derived products, pathogens, and cells into the brain that is essential for normal neuronal functioning and... 
VASCULAR CELLS | ALZHEIMERS-DISEASE BRAIN | DISRUPTION | PERMEABILITY | INTEGRITY | GENOTYPE | NEURODEGENERATION | DISORDERS | NEUROSCIENCES | PERICYTES | CYCLOPHILIN | Thalamus - metabolism | Humans | Middle Aged | Male | Case-Control Studies | Cerebral Cortex - metabolism | Brain - metabolism | Young Adult | Aged, 80 and over | CA3 Region, Hippocampal - metabolism | Adult | Albumins - cerebrospinal fluid | CA1 Region, Hippocampal - metabolism | Female | Neostriatum - metabolism | Dentate Gyrus - metabolism | Cognitive Dysfunction - metabolism | Pericytes - metabolism | Permeability | Blood-Brain Barrier - metabolism | Caudate Nucleus - metabolism | Hippocampus - metabolism | Magnetic Resonance Imaging | Serum Albumin | Aged | Aging - metabolism | Brain | Alzheimer's disease | Neurophysiology | Medical colleges | Neurons | Cognitive ability | Proteins | Studies | Neurotoxicity | Brain research | Blood-brain barrier | Aging | Biomarkers | Extracellular matrix | Alzheimers disease | Age | Index Medicus | living human brain | high resolution magnetic resonance imaging | cognitive impairment | hippocampus | Blood-brain barrier breakdown
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9. Full Text DOPAMINE RESPONSIVE FEATURES IN ALZHEIMER'S DISEASE, ALZHEIMER'S DISEASE WITH LEWY BODIES (LB), AND PURE LB DISEASE
by Ringman, John M and Caceres, Nenette and Clark, Kristi and Chui, Helena C
Alzheimer's & Dementia, ISSN 1552-5260, 07/2016, Volume 12, Issue 7, pp. P737 - P738
Alzheimer's disease
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10. Full Text Differential effects of ischemic vascular disease and Alzheimer's disease on brain atrophy and cognition
by Zheng, Ling and Vinters, Harry V and Mack, Wendy J and Weiner, Michael W and Chui, Helena C and IVD Program Project and IVD program project
Journal of Cerebral Blood Flow and Metabolism, ISSN 0271-678X, 01/2016, Volume 36, Issue 1, pp. 204 - 215
We previously reported that pathologic measures of arteriosclerosis (AS), cerebral infarction, and Alzheimer's disease (AD) are independently correlated with... 
brain imaging | cerebrovascular disease | cognition | Alzheimer's | NEUROFIBRILLARY TANGLES | CEREBRAL ATHEROSCLEROSIS | RISK-FACTORS | DEMENTIA | PATHOLOGY | NEUROSCIENCES | CEREBROVASCULAR-DISEASE | DECLINE | OLDER PERSONS | ENDOCRINOLOGY & METABOLISM | HEMATOLOGY | ASSOCIATION | Brain Ischemia - complications | Dementia, Vascular - psychology | Dementia, Vascular - complications | Alzheimer Disease - complications | Prospective Studies | Humans | Cognition Disorders - pathology | Male | Alzheimer Disease - pathology | Atrophy | Neuropsychological Tests | Magnetic Resonance Imaging | Autopsy | Cognition Disorders - etiology | Brain Ischemia - pathology | Brain Ischemia - psychology | Aged, 80 and over | Brain - pathology | Dementia, Vascular - pathology | Female | Longitudinal Studies | Alzheimer Disease - psychology | Cognition Disorders - psychology | Databases, Factual | Index Medicus
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11. Full Text APOE4 AGGREGATION AND HYPOLIPIDATION IS IMPLICATED IN ALZHEIMER’S DISEASE PATHOLOGY IN CELLULAR, ANIMAL AND HUMAN STUDIES
by Yassine, Hussein N and Rawat, Varun and Liraz, Ori and Johansson, Jan O and Chui, Helena C and Harrington, Michael and Michaelson, Daniel M
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1537 - P1537
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12. Full Text APOE4 AGGREGATION AND HYPOLIPIDATION IS IMPLICATED IN ALZHEIMER’S DISEASE PATHOLOGY IN CELLULAR, ANIMAL AND HUMAN STUDIES
by Yassine, Hussein N and Rawat, Varun and Liraz, Ori and Johansson, Jan O and Chui, Helena C and Harrington, Michael and Michaelson, Daniel M
Alzheimer's & Dementia, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, p. P1537
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13. Associations Between Serum Cholesterol Levels and Cerebral Amyloidosis
by Bruce Reed and Sylvia Villeneuve and Wendy Mack and Charles DeCarli and Helena C Chui and William Jagust
JAMA Neurology, ISSN 2168-6149, 02/2014, Volume 71, Issue 2, pp. 195 - 195
  Because deposition of cerebral β-amyloid (Aβ) seems to be a key initiating event in Alzheimer disease (AD), factors associated with increased deposition are... 
Stroke | Correlation analysis | Tomography | Cardiovascular disease | Lipids | Alzheimers disease | Cholesterol | Age
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14. Full Text Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
by Sims, Rebecca and Van Der Lee, Sven J and Naj, Adam C and Bellenguez, Céline and Badarinarayan, Nandini and Jakobsdottir, Johanna and Kunkle, Brian W and Boland, Anne and Raybould, Rachel and Bis, Joshua C and Martin, Eden R and Grenier-Boley, Benjamin and Heilmann-Heimbach, Stefanie and Chouraki, Vincent and Kuzma, Amanda B and Sleegers, Kristel and Vronskaya, Maria and Ruiz, Agustin and Graham, Robert R and Olaso, Robert and Hoffmann, Per and Grove, Megan L and Vardarajan, Badri N and Hiltunen, Mikko and Nöthen, Markus M and White, Charles C and Hamilton-Nelson, Kara L and Epelbaum, Jacques and Maier, Wolfgang and Choi, Seung-Hoan and Beecham, Gary W and Dulary, Cécile and Herms, Stefan and Smith, Albert V and Funk, Cory C and Derbois, Céline and Forstner, Andreas J and Ahmad, Shahzad and Li, Hongdong and Bacq, Delphine and Harold, Denise and Satizabal, Claudia L and Valladares, Otto and Squassina, Alessio and Thomas, Rhodri and Brody, Jennifer A and Qu, Liming and Sánchez-Juan, Pascual and Morgan, Taniesha and Wolters, Frank J and Zhao, Yi and Garcia, Florentino Sanchez and Denning, Nicola and Fornage, Myriam and Malamon, John and Naranjo, Maria Candida Deniz and Majounie, Elisa and Mosley, Thomas H and Dombroski, Beth and Wallon, David and Lupton, Michelle K and Dupuis, Josée and Whitehead, Patrice and Fratiglioni, Laura and Medway, Christopher and Jian, Xueqiu and Mukherjee, Shubhabrata and Keller, Lina and Brown, Kristelle and Lin, Honghuang and Cantwell, Laura B and Panza, Francesco and McGuinness, Bernadette and Moreno-Grau, Sonia and Burgess, Jeremy D and Solfrizzi, Vincenzo and Proitsi, Petra and Adams, Hieab H and Allen, Mariet and Seripa, Davide and Pastor, Pau and Cupples, L Adrienne and Price, Nathan D and Hannequin, Didier and Frank-García, Ana and Levy, Daniel and Chakrabarty, Paramita and Caffarra, Paolo and Giegling, Ina and Beiser, Alexa S and Giedraitis, Vilmantas and Hampel, Harald and Garcia, Melissa E and Wang, Xue and Lannfelt, Lars and Mecocci, Patrizia and Eiriksdottir, Gudny and Crane, Paul K and Pasquier, Florence and Boccardi, Virginia and ... and EADI and GERAD PERADES and ARUKConsortium and CHARGE and ADGC and GERAD/PERADES, CHARGE, ADGC, EADI and ARUK Consortium and Stockholms universitet and Centrum för forskning om äldre och åldrande (ARC), (tills m KI) and Samhällsvetenskapliga fakulteten
Nature Genetics, ISSN 1061-4036, 09/2017, Volume 49, Issue 9, pp. 1373 - 1384
We identified rare coding variants associated with Alzheimer's disease in a three-stage case-control study of 85,133 subjects. In stage 1, we genotyped 34,174... 
COMMON VARIANTS | IDENTIFIES VARIANTS | METAANALYSIS | GENOTYPE IMPUTATION | LOW-FREQUENCY | SUSCEPTIBILITY | GENETICS & HEREDITY | RISK | LOCI | WAVE2 COMPLEX | GENOME-WIDE ASSOCIATION | Amino Acid Sequence | Microglia - metabolism | Genetic Predisposition to Disease - genetics | Gene Frequency | Humans | Immunity, Innate - genetics | Genotype | Gene Expression Profiling | Case-Control Studies | Linkage Disequilibrium | Membrane Glycoproteins - genetics | Sequence Homology, Amino Acid | Exome - genetics | Protein Interaction Maps - genetics | Adaptor Proteins, Signal Transducing - genetics | Phospholipase C gamma - genetics | Polymorphism, Single Nucleotide | Alzheimer Disease - genetics | Odds Ratio | Receptors, Immunologic - genetics | Immune response | Genetic variation | Physiological aspects | Development and progression | Genetic aspects | Research | Alzheimer's disease | Neurodegenerative diseases | Genes | Genomics | Health risks | Innate immunity | Genomes | Disease control | Immunity | Microglia | Proteins | Immune systems | Studies | Consortia | DNA microarrays | Genotyping | Gene frequency | DNA methylation | Alzheimers disease | Protein interaction | Bioinformatics | Genotypes | Index Medicus | Biological Sciences | Naturvetenskap | Natural Sciences | Biologiska vetenskaper
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15. Full Text RACIAL-ETHNIC DISPARITIES IN ALZHEIMER’S RISK: ROLE OF EXPOSURE TO AMBIENT FINE PARTICLES
by Younan, Diana and Wang, Xinhui and Lurmann, Fred and Serre, Marc and Vizuete, William and He, Ka and Braskie, Meredith N and Gatz, Margaret and Chui, Helena C and Espeland, Mark A and Chen, Jiu-Chiuan
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P1613 - P1613
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16. Full Text DOPAMINE RESPONSIVE FEATURES IN ALZHEIMER'S DISEASE, ALZHEIMER'S DISEASE WITH LEWY BODIES (LB), AND PURE LB DISEASE
by Ringman, John M and Caceres, Nenette and Clark, Kristi and Chui, Helena C
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 2016, Volume 12, Issue 7, pp. P737 - P738
Neurology
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17. Full Text QUANTIFYING MEMORY RESERVE VIA VARIANCE DECOMPOSITION IN A GEOGRAPHICALLY DIVERSE SAMPLE OF OLDER WOMEN
by Petkus, Andrew J and Espeland, Mark A and Resnick, Susan M and Wang, Xinhui and Younan, Diana and Rapp, Stephen R and Hayden, Kathleen M and Gatz, Margaret and Chui, Helena C and Shumaker, Sally A and Chen, Jiu-Chiuan
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2018, Volume 14, Issue 7, pp. P570 - P571
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18. Full Text DEVELOPMENT OF AN IPSC-BASED BIOMARKER STRATEGY TO IDENTIFY NEUROREGENERATIVE RESPONDERS TO ALLOPREGNANOLONE
by Solinsky, Christine M and Park, Jenny Ayoung and Chui, Helena C and Blurton-Jones, Mathew and Ichida, Justin K and Brinton, Roberta Diaz
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P998 - P998
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19. Full Text Ambient air pollution and neurotoxicity on brain structure: Evidence from women's health initiative memory study
: Neurotoxic Air Pollution and WMV
by Chen, Jiu-Chiuan and Wang, Xinhui and Wellenius, Gregory A and Serre, Marc L and Driscoll, Ira and Casanova, Ramon and McArdle, John J and Manson, JoAnn E and Chui, Helena C and Espeland, Mark A
Annals of Neurology, ISSN 0364-5134, 09/2015, Volume 78, Issue 3, pp. 466 - 476
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20. Full Text THE ABCA-1 AGONIST (CS-6253) REVERSES APOE4 HYPOLIPIDATION IN ALZHEIMER’S DISEASE
by Rawat, Varun and Feng, Qingru and Michaelson, Daniel M and Chui, Helena C and Fonteh, Alfred and Johansson, Jan O and Bielicki, John K and Harrington, Michael and Yassine, Hussein N
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, ISSN 1552-5260, 07/2017, Volume 13, Issue 7, pp. P1257 - P1257
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