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American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 06/2011, Volume 300, Issue 6, pp. 929 - 938
Inflammatory bowel diseases (IBDs), mainly Crohn's disease and ulcerative colitis, are dynamic, chronic inflammatory conditions that are associated with an... 
Citrullination | Inflammation | Apoptosis | PROTEIN ARGININE DEIMINASE-4 | RHEUMATOID-ARTHRITIS | PHYSIOLOGY | citrullination | ULCERATIVE-COLITIS | apoptosis | COLON-CANCER | INFLAMMATORY-BOWEL-DISEASE | MULTIPLE-SCLEROSIS | inflammation | GASTROENTEROLOGY & HEPATOLOGY | SPHINGOSINE KINASE | EXPRESSION | ASSOCIATION | Dextran Sulfate | Up-Regulation | Colon - enzymology | Apoptosis - drug effects | Humans | Citrulline - metabolism | Colon - drug effects | Gastrointestinal Agents - administration & dosage | Ornithine - analogs & derivatives | Colitis - pathology | Dose-Response Relationship, Drug | Enzyme Inhibitors - administration & dosage | Protein Processing, Post-Translational - drug effects | Colitis - chemically induced | Enzyme Inhibitors - toxicity | Anti-Inflammatory Agents - administration & dosage | Gastrointestinal Agents - toxicity | Disease Models, Animal | Hydrolases - metabolism | Administration, Oral | Anti-Inflammatory Agents - pharmacology | Colon - pathology | Anti-Inflammatory Agents - toxicity | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Ornithine - pharmacology | HT29 Cells | Gastrointestinal Agents - pharmacology | Animals | Colitis - enzymology | Ornithine - administration & dosage | Mice | Ornithine - toxicity | Colitis - prevention & control | Arginine - metabolism | Protein-Arginine Deiminases | Hydrolases - antagonists & inhibitors | Physiological aspects | Amidines | Colitis | Research | Inflammatory bowel disease | Side effects | Cytokines | Risk assessment | Rodents | Crohns disease | Index Medicus | Mediators | Immunity
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2012, Volume 109, Issue 35, pp. 14007 - 14012
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e53791 - e53791
Protein Arginine Deiminases (PADs) catalyze the post-translational conversion of peptidyl-Arginine to peptidyl-Citrulline in a calcium-dependent, irreversible... 
CITRULLINATION | PAD4 | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | PEPTIDYLARGININE DEIMINASE | GENE-EXPRESSION | DOWN-REGULATION | INACTIVATORS | SUPPRESSION | MIR-16 FAMILY | P53 | Colonic Neoplasms - genetics | Hydrolases - genetics | Colonic Neoplasms - drug therapy | Humans | MicroRNAs - metabolism | G1 Phase - drug effects | Enzyme Inhibitors - chemical synthesis | Cyclin E - genetics | Colonic Neoplasms - metabolism | Tumor Suppressor Protein p53 - genetics | Protein Isoforms - metabolism | Tumor Suppressor Protein p53 - agonists | Cell Cycle Checkpoints - genetics | G1 Phase - genetics | Gene Expression Regulation, Neoplastic - drug effects | Amidines - chemical synthesis | Hydrolases - metabolism | Signal Transduction | Cyclin-Dependent Kinase 6 - genetics | Enzyme Inhibitors - pharmacology | Tumor Suppressor Protein p53 - metabolism | Cyclin-Dependent Kinase 6 - metabolism | Cell Cycle Checkpoints - drug effects | Colonic Neoplasms - pathology | Cell Line, Tumor | Amidines - pharmacology | MicroRNAs - genetics | Cyclin E - metabolism | Cyclin D - genetics | Cyclin D - metabolism | Protein-Arginine Deiminases | Hydrolases - antagonists & inhibitors | Protein Isoforms - genetics | Colon cancer | MicroRNA | Arginine | Tumor proteins | Cancer cells | Cell cycle | Cell culture | Calcium | Laboratories | p53 Protein | Colorectal cancer | Kinases | Carcinogenesis | Arginine deiminase | Proteins | Carcinogens | Penicillin | Post-translation | Colon | Inhibition | Chronic illnesses | Medical research | Enzymes | Research & development--R&D | MiRNA | Citrulline | Mammals | Gene expression | Cyclins | Inflammatory bowel disease | Ribonucleic acids | MicroRNAs | Pharmacy | Tumor suppressor genes | Cancer | Apoptosis | Index Medicus | Research & development | R&D
Journal Article
Current Cancer Drug Targets, ISSN 1568-0096, 10/2015, Volume 15, Issue 8, pp. 739 - 749
CDK8 and its paralog CDK19, in complex with CCNC, MED12 and MED13, are transcriptional regulators that mediate several carcinogenic pathways and the... 
MED12 | CDK8 | CDK19 | MED13 | Cyclin C | Tissue microarrays | Breast cancer | Microarray data mining | SURVIVAL | PHYLLODES TUMORS | ACTIVATION | MEDIATOR | KINASE | microarray data mining | tissue microarrays | FREQUENT MED12 MUTATIONS | ONCOLOGY | TUMOR-SUPPRESSOR | SUBCOMPLEX | MICROARRAY DATA | PROGRESSION
Journal Article
Cancer Research, ISSN 0008-5472, 12/2018, Volume 78, Issue 23, pp. 6594 - 6606
Unresectable hepatic metastases of colon cancer respond poorly to existing therapies and are a major cause of colon cancer lethality. In this study, we... 
TRANSITION | DEPENDENT KINASE 8 | ACTIVATION | TGF-BETA | MICROENVIRONMENT | ONCOLOGY | PHOSPHORYLATION | ELONGATION | STIMULATE | TRANSCRIPTION | TISSUE INHIBITOR
Journal Article
Cancer Research, ISSN 0008-5472, 05/2015, Volume 75, Issue 9 Supplement, pp. P4 - P4-15-13
Journal Article
Cancer Research, ISSN 0008-5472, 10/2014, Volume 74, Issue 19 Supplement, pp. 2101 - 2101
Journal Article
Journal Article
Current cancer drug targets, 2015, Volume 15, Issue 8, p. 739
CDK8 and its paralog CDK19, in complex with CCNC, MED12 and MED13, are transcriptional regulators that mediate several carcinogenic pathways and the... 
Cyclin C - genetics | Breast Neoplasms - genetics | Humans | Cyclin-Dependent Kinase 8 - genetics | Female | Biomarkers, Tumor - genetics | Breast Neoplasms - diagnosis | Transcription Factors | Cyclin-Dependent Kinases - genetics
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 08/2012, Volume 109, Issue 35, pp. 14007 - 14012
The role of NF-[kappa]B activation in tumor initiation has not been thoroughly investigated. We generated Ikk[beta][(EE).sup.IEC] transgenic mice expressing... 
Epithelial cells | Tumor necrosis factor | DNA damage | Physiological aspects | Genetic aspects | Research | Health aspects | Phosphotransferases | Enzymes | Rodents | Colon | Kinases | Cells | Tumors
Journal Article
Cancer Research, ISSN 0008-5472, 04/2012, Volume 72, Issue 8 Supplement, pp. LB-168 - LB-168
Journal Article
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