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by Gu, KN and Bang, SY and Lee, HS and Park, Y and Kang, JY and Kim, JS and Nam, B and Yoo, HS and Shin, JM and Lee, YK and Lee, TH and Chun, S and Cho, SK and Choi, CB and Sung, YK and Kim, TH and Jun, JB and Yoo, DH and Kim, K and Bae, SC
ARTHRITIS RESEARCH & THERAPY, ISSN 1478-6354, 08/2019, Volume 21, Issue 1, pp. 195 - 7
Background Structural variations such as copy number variations (CNVs) have a functional impact on various human traits. This study profiled genome-wide CNVs... 
CONCOMITANT METHOTREXATE | ADALIMUMAB | GOLIMUMAB | VALIDATION | MONOCLONAL-ANTIBODY | RHEUMATOLOGY | ANTITUMOR NECROSIS FACTOR | THERAPY | Copy number variations | Rheumatoid arthritis | TNF-alpha blockers | Drug efficacy | ETANERCEPT | INFLIXIMAB | DISEASE-ACTIVITY SCORE | Genomes | Health risk assessment | Drug therapy | Binding sites | TNF-α blockers
Journal Article
Gastrointestinal Endoscopy, ISSN 0016-5107, 06/2019, Volume 89, Issue 6, pp. AB403 - AB403
Journal Article
by Kwon, YC and Chun, S and Kim, K and Mak, A
CELLS, ISSN 2073-4409, 10/2019, Volume 8, Issue 10, p. 1180
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease of complex etiology that primarily affects women of childbearing age. The development of SLE... 
IMMUNE-RESPONSE | SUSCEPTIBILITY LOCI | HLA ALLELES | IGA DEFICIENCY | lupus | SLE | epigenetics | FC-GAMMA-RIIB | CELL BIOLOGY | genome | INTERFERON | genetics | IMMUNOGLOBULIN-A | MYASTHENIA-GRAVIS | RISK VARIANTS | T-CELLS | sle
Journal Article
by Lee, H and Lee, E and Kim, N and Kim, JH and Park, K and Chun, J and Shin, JI and Chang, JS and Kim, JS
FRONTIERS IN ONCOLOGY, ISSN 2234-943X, 04/2019, Volume 9, p. 239
Background: While atlas segmentation (AS) has proven to be a time-saving and promising method for radiation therapy contouring, optimal methods for its use... 
atlas-based auto-segmentation | IMRT | ONCOLOGY | auto-contouring | PERFORMANCE | segmentation | TIMESAVINGS | atlas segmentation | contouring | Image segmentation | Evaluation | Usage | Head and neck cancer | Diagnosis | Health aspects | Computer-aided medical diagnosis | Methods
Journal Article
Arthritis Research & Therapy, ISSN 1478-6354, 08/2019, Volume 21, Issue 1
Structural variations such as copy number variations (CNVs) have a functional impact on various human traits. This study profiled genome-wide CNVs in Korean... 
Care and treatment | Genome-wide association studies | Usage | Arthritics | Tumor necrosis factor inhibitors | Copy number variations | Analysis | Genetic aspects
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2013, Volume 435, Issue 2, pp. 274 - 281
Glycogen synthase kinase-3 (GSK-3) is emerging as a prominent therapeutic target of Alzheimer’s disease (AD). A number of studies have been undertaken to... 
TAU | GSK-3 inhibitor | Alzheimer’s disease | Amyloid-beta
Journal Article
Journal Article
Journal Article
Journal Article
World Journal of Oncology, ISSN 1920-4531, 2015, Volume 6, Issue 4, pp. 410 - 415
Chemotherapy-induced neutropenia (CIN) may compromise planned chemotherapy, resulting in severe infection, dose reduction or delayed treatment. Orally... 
Chemotherapy-induced neutropenia | Gemcitabine | G-CSF | Pancreatic cancer | PLAG | Original
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 08/2012, Volume 21, Issue 8, p. 1533
A series of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors, 5-oxo-2,4,5,6-tetrahydro-1H-thiopyrano[3,4-c]quinoline-9-carboxamide derivatives, were... 
Alkaloids | Enzymes | Biological products | Analysis | Quinoline
Journal Article
Medicinal Chemistry Research, ISSN 1054-2523, 8/2012, Volume 21, Issue 8, pp. 1533 - 1543
A series of poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors, 5-oxo-2,4,5,6-tetrahydro-1H-thiopyrano[3,4-c]quinoline-9-carboxamide derivatives, were... 
Biochemistry, general | Biomedicine | Poly(ADP-ribose)polymerase | PARP-1 inhibitor | Pharmacology/Toxicology | Thiopyranoquinoline derivatives | Cell Biology | SITE | CHEMISTRY, MEDICINAL | DNA-DAMAGE | DEPLETION | CANCER | DISCOVERY | CELL-DEATH | TEMOZOLOMIDE | POTENT | NAD(+) | CHEMOPOTENTIATION
Journal Article
Bulletin of the Korean Chemical Society, ISSN 0253-2964, 05/2011, Volume 32, Issue 5, pp. 1650 - 1656
A series of potent tricyclic derivatives with a non-aromatic amide as potent PARP-1 inhibitors were successfully synthesized and their PARP-1 inhibitory... 
Phenanthridines | Poly(ADP-ribose)polymerase | PARP-1 inhibitor | POLYMERASE-1 INHIBITORS | POTENT | INFLAMMATION | ISCHEMIA | CANCER | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY
Journal Article
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