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NATURE COMMUNICATIONS, ISSN 2041-1723, 07/2019, Volume 10, Issue 1, pp. 3399 - 13
Identifying driver genes from somatic mutations is a central problem in cancer biology. Existing methods, however, either lack explicit statistical models, or... 
HETEROGENEITY | EVOLUTION | SIGNATURES | SERVER | MULTIDISCIPLINARY SCIENCES | PATTERNS | ONTOLOGY | EXPRESSION | SOMATIC MUTATIONS | RNA modification | Statistical analysis | Computer simulation | Genes | Positive selection | Methyltransferase | Bladder | mRNA | Mutation rates | Clustering | Annotations | Statistical models | Tumor suppressor genes | Tumorigenesis | Mathematical models | Mutation | Statistical modelling | Cancer | Tumors
Journal Article
Clinical Nuclear Medicine, ISSN 0363-9762, 12/2019, Volume 44, Issue 12, pp. 936 - 942
PURPOSEAs well as in many others cancers, FDG uptake is correlated with the degree of malignancy in gliomas, that is, commonly high FDG uptake in high-grade... 
Journal Article
HPB, ISSN 1365-182X, 2019
Background: Posthepatectomy liver failure (PHLF) is the main limitation to extending liver resection but its pathophysiology is not yet fully understood. The... 
Journal Article
IEEE/ACM Transactions on Computational Biology and Bioinformatics, ISSN 1545-5963, 9/2019, pp. 1 - 1
Genome-scale reconstructed metabolic networks have provided an organism specific understanding of cellular processes and their relations to phenotype. As they... 
Genome-scale reconstructed metabolic networks | metabolism | online workbench | metabolomics
Journal Article
Bioinformatics, ISSN 1367-4803, 09/2019, Volume 35, Issue 18, pp. 3433 - 3440
Abstract Motivation Whole exome sequencing (WES) studies for autism spectrum disorder (ASD) could identify only around six dozen risk genes to date because the... 
PATHWAYS | NETWORK | PROTEIN | BIOCHEMICAL RESEARCH METHODS | AUTISM SPECTRUM DISORDER | HAPLOINSUFFICIENCY | DE-NOVO MUTATIONS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MATHEMATICAL & COMPUTATIONAL BIOLOGY | REGULATORS | EPILEPSY | DIFFERENTIATION | IMPLICATE
Journal Article
IEEE/ACM Transactions on Computational Biology and Bioinformatics, ISSN 1545-5963, 8/2019, pp. 1 - 1
Phenotypic heritability of complex traits and diseases is seldom explained by individual genetic variants identified in genome-wide association studies (GWAS).... 
Greedy algorithms | SNP-SNP Networks | GWAS | Hi-C | Genomics | Submodular Function | Prediction algorithms | Phenotype Prediction | Bioinformatics | SNP Selection | Optimization
Journal Article
IEEE/ACM Transactions on Computational Biology and Bioinformatics, ISSN 1545-5963, 6/2019, pp. 1 - 1
1H High-Resolution Magic Angle Spinning (HRMAS) Nuclear Magnetic Resonance (NMR) is a reliable technology used for detecting metabolites in solid tissues. Fast... 
Spectroscopy | Metabolomics | Correlation | HSQC NMR | HRMAS NMR | Two dimensional displays | Surgery | Cavity resonators | Nuclear magnetic resonance | Tumors
Journal Article
02/2019
A large proportion of the basepairs in the long reads that third-generation sequencing technologies produce possess sequencing errors. These errors propagate... 
Journal Article
Bioinformatics, ISSN 1367-4803, 02/2019, Volume 35, Issue 3, pp. 365 - 371
Abstract Motivation Genomic data-sharing beacons aim to provide a secure, easy to implement and standardized interface for data-sharing by only allowing yes/no... 
PRIVACY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | BIOCHEMICAL RESEARCH METHODS | MATHEMATICAL & COMPUTATIONAL BIOLOGY
Journal Article
Nucleic Acids Research, ISSN 0305-1048, 11/2018, Volume 46, Issue 21, pp. e125 - e125
Abstract Choosing whether to use second or third generation sequencing platforms can lead to trade-offs between accuracy and read length. Several types of... 
ACCURATE | HUMAN GENOME | ALIGNMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | Computational Biology - methods | Reproducibility of Results | Algorithms | Humans | Software | High-Throughput Nucleotide Sequencing - methods | Machine Learning | Methods Online
Journal Article
The American Journal of Human Genetics, ISSN 0002-9297, 06/2018, Volume 102, Issue 6, pp. 1169 - 1184
Journal Article
ONCOTARGET, ISSN 1949-2553, 09/2017, Volume 8, Issue 42, pp. 71597 - 71617
Pediatric high grade glioma (pHGGs), including sus-tentorial and diffuse intrinsic pontine gliomas, are known to have a very dismal prognosis. For instance,... 
CANCER-CELLS | HIF1alpha | ANGIOGENESIS | TOPOISOMERASE-I | HYPOXIA | targets | pediatric | CELL BIOLOGY | GLIOBLASTOMA | DIFFUSE INTRINSIC PONTINE | MYC | mTor | CENTRAL-NERVOUS-SYSTEM | high grade glioma | HISTONE H3.3 | MUTATIONS
Journal Article
Turkish Journal of Biology, ISSN 1300-0152, 2017, Volume 41, Issue 2, pp. 333 - 341
Neurodevelopment is a dynamic and complex process, which involves interactions of thousands of genes. Understanding the mechanisms of brain development is... 
Neurodevelopment | BrainSpan | k-Shell decomposition | Bioinformatics | Coexpression network | Computational biology | computational biology | HUMAN BRAIN | AUTISM | INTERNET | TRANSCRIPTOME | SCHIZOPHRENIA | DISORDERS | YEAST | neurodevelopment | DE-NOVO MUTATIONS | bioinformatics | BIOLOGY | coexpression network | IMPLICATE | WORLD
Journal Article
European Neuropsychopharmacology, ISSN 0924-977X, 2017, Volume 27, p. S437
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1016/j.euroneuro.2016.09.497... 
Autism | Brain | Chromatin | Neural circuitry | Neurons | Analysis | Genetic transcription | Neurophysiology
Journal Article