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Journal Article
PLoS ONE, ISSN 1932-6203, 06/2016, Volume 11, Issue 6, p. e0157458
Objective In developed countries with westernized diets, the excessive consumption of added sugar in beverages and highly refined and processed foods is... 
DIABETES-MELLITUS | KIDNEY-DISEASE | METABOLIC SYNDROME | CIRCULATING CONCENTRATIONS | SOFT DRINK CONSUMPTION | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | FRUCTOSE INFUSION | SUGAR-SWEETENED BEVERAGES | OVERWEIGHT/OBESE HUMANS | CHOW-FED RATS | Hypertriglyceridemia - drug therapy | Phytochemicals - chemistry | Phytochemicals - administration & dosage | Plant Extracts - chemistry | Petroselinum - chemistry | Humans | Hypertriglyceridemia - metabolism | Garcinia mangostana - chemistry | Angelica archangelica - chemistry | Fructose - metabolism | Hep G2 Cells | Enzyme Inhibitors - administration & dosage | Plant Extracts - administration & dosage | Insulin - metabolism | Fructokinases - antagonists & inhibitors | Enzyme Inhibitors - chemistry | Fructokinases - chemistry | Oxidative Stress - drug effects | Fructose - chemistry | Sugar substitutes | Physiological aspects | Metabolic diseases | Research | Health aspects | Risk factors | Fructose | Developed countries | Oxidative stress | Liver | Cardiovascular disease | Glucose | Kinases | Metabolic syndrome | Proteins | Ketohexokinase | Lysates | Elevation | Rodents | Inhibition | Beverages | Heart diseases | Sugar | Sugars | Recombinant | Food | Hypertension | Obesity | Research & development--R&D | Diabetes mellitus | Health risks | Uric acid | Food processing | Acid production | Metabolism | Medical screening | Insulin | Biological activity | Medicine | Nutrition research | Weight control | Depletion | Diet | Acids | Hypertriglyceridemia | Insulin resistance | Lifestyles | Kidney diseases | Cardiovascular diseases | Human behavior | In vitro methods and tests | ATP | Research & development | R&D
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47948
Excessive dietary fructose intake may have an important role in the current epidemics of fatty liver, obesity and diabetes as its intake parallels the... 
HYPERINSULINEMIC MEN | HOMEOSTASIS | ACTIVATED PROTEIN-KINASE | RISK-FACTORS | RAT | GLUCOSE | MULTIDISCIPLINARY SCIENCES | DISEASE | STEATOHEPATITIS | EXPRESSION | DIETARY FRUCTOSE | Fatty Liver - genetics | Liver - pathology | Fatty Liver - metabolism | Uric Acid - metabolism | Fatty Liver - pathology | Humans | Liver - metabolism | Transcriptional Activation | Enzyme Inhibitors - pharmacology | Rats | Hepatocytes - pathology | Male | Hepatocytes - metabolism | Rats, Sprague-Dawley | Fructokinases - metabolism | Fructose - metabolism | Hep G2 Cells | Up-Regulation - drug effects | Animals | Uric Acid - antagonists & inhibitors | Fructokinases - genetics | Allopurinol - pharmacology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Hepatocytes - drug effects | Type 2 diabetes | Phosphates | Obesity | Fatty liver | Physiological aspects | Insulin resistance | Triglycerides | Uric acid | Fructose | Epidemics | Oxidative stress | Nephrology | Liver | Activation | Glucose | Kinases | Experiments | Proteins | Hyperuricemia | Rodents | Transcription activation | Sensitizing | Hypertension | Liver diseases | Diabetes mellitus | Metabolic diseases | Dietary intake | Metabolism | Acid production | Insulin | Medicine | Diet | Acids | Hepatocytes | Hypertriglyceridemia | Fructokinase | Diabetes | Kidney diseases | Laboratory animals | Metabolic disorders
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2017, Volume 12, Issue 1, p. e0169137
Background Epidemics of chronic kidney disease (CKD) not due to diabetes mellitus (DM) or hypertension have been observed among individuals working in hot... 
NICARAGUAN SUGARCANE WORKERS | MARKER | DEHYDRATION | MULTIDISCIPLINARY SCIENCES | VASOPRESSIN | URINE VOLUME | WATER-INTAKE | COPEPTIN | RENAL INJURY | MESOAMERICAN NEPHROPATHY | PROGRESSION | Urinary Calculi - blood | Prevalence | Cross-Sectional Studies | Renal Insufficiency, Chronic - etiology | Humans | Japan | Middle Aged | Risk Factors | Urinary Calculi - epidemiology | Male | Sodium - blood | Renal Insufficiency, Chronic - blood | Renal Insufficiency, Chronic - epidemiology | Osmolar Concentration | Adolescent | Sex Factors | Adult | Female | Retrospective Studies | Urinary Calculi - complications | Complications and side effects | Osmosis | Research | Chronic kidney failure | Sodium | Risk factors | Health care | Epidemics | Salts | Nephrology | Heart attacks | Transplants & implants | Laboratories | Dyslipidemia | Dehydration | Body mass index | Hyperuricemia | Rodents | Population | Heat stress | Drug therapy | Cardiology | Sugarcane | Hypertension | Creatinine | Obesity | Osmolarity | Diabetes mellitus | Health risks | Risk reduction | Regression analysis | Preventive medicine | Risk analysis | Vasopressin | Studies | Injury prevention | Hospitals | Body mass | Body size | Aldehyde reductase | Fructokinase | Heat tolerance | Kidney diseases | Diabetes | Osmotic pressure | Potassium | Kidney transplantation | Reductase
Journal Article
Journal Article
American journal of physiology. Renal physiology, ISSN 1931-857X, 08/2019, Volume 317, Issue 4, pp. F941 - F948
Obesity, as well as the metabolic syndrome, are well known risk factors for chronic kidney disease (CKD), but less is known about the mechanism(s) by which... 
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2012, Volume 7, Issue 11, p. e48801
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, p. e0123509
Journal Article