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Current Medicinal Chemistry, ISSN 0929-8673, 06/2016, Volume 23, Issue 18, p. 1802
In this review we discuss drug design strategies directed to the development of potential anti-influenza A(H1N1) inhibitors of M2 ion channel, neuraminidase... 
Viruses | Drug development | Ribonucleic acid--RNA | DNA-directed RNA polymerase | Design optimization | Polymerase | Swine flu | Exo-a-sialidase | Influenza | Computer applications | Hemagglutinins | Ion channels | Chronology
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 09/2016, Volume 55, Issue 38, pp. 11303 - 11303
Non‐enzymatic variations of posttranslational modifications (nPTMs) form through reactions of electrophilic metabolites (here, in the eye) with nucleophilic... 
chaperone proteins | biological activity | protein modifications | argpyrimidine | protein semisynthesis | Proteins | Eye | Arginine | Metabolites | Workers | Hsp27 protein | Heat shock proteins | Heat shock
Journal Article
Journal Article
Journal of Enzyme Inhibition and Medicinal Chemistry, ISSN 1475-6366, 01/2017, Volume 32, Issue 1, pp. 214 - 230
The 5-hydroxytryptamine (5-HT 1A ) receptors represent an attractive target in drug discovery. In particular, 5-HT 1A agonists and partial agonists are deeply... 
3D-QSAR | Adrenoreceptor | 5HT1A-ligands | CoMFA | CoMSIA | 5HT | ligands | CHEMISTRY, MEDICINAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | RECEPTOR | ALPHA | MOLECULAR DOCKING | DISCOVERY | STRUCTURE-AFFINITY/ACTIVITY RELATIONSHIPS | POTENCY | INHIBITORS | DERIVATIVES | TOOL | Ligands | Index Medicus
Journal Article
Journal Article
RSC Advances, ISSN 2046-2069, 2016, Volume 6, Issue 66, pp. 61088 - 61108
The development of selective ligands binding to specific PDE isoforms represents an urgent need in medicinal chemistry, being a necessary strategy to identify... 
CELLS | AND-4 DUAL INHIBITOR | MODELS | CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES | CLONING | DOCKING | EXPRESSION | BINDING | CHEMISTRY, MULTIDISCIPLINARY | YM-393059 | Enzymes | Inhibitors | Computation | Strategy | Mathematical models | Selectivity | Derivatives | Computer programs
Journal Article