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Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2017, Volume 76, Issue Suppl 1, p. A36
BackgroundMonocytes play an important role in autoimmune disease including rheumatoid arthritis (RA) or systemic sclerosis (SSc). Monocytes are the first... 
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e115596
Background: Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterised by skin and internal organs fibrosis due to accumulation of extra... 
PATHOGENESIS | MATRIX METALLOPROTEINASES | COLLAGEN EXPRESSION | MYOCARDIAL-INFARCTION | TAK1 | MULTIDISCIPLINARY SCIENCES | LIVER FIBROSIS | GENE-EXPRESSION | TISSUE INHIBITOR | GROWTH-FACTOR | MICRORNAS | Dermis - metabolism | Extracellular Matrix Proteins - biosynthesis | Tissue Inhibitor of Metalloproteinase-1 - biosynthesis | Extracellular Matrix Proteins - genetics | Humans | Scleroderma, Systemic - metabolism | Gene Expression Regulation | Scleroderma, Systemic - genetics | Scleroderma, Systemic - pathology | 3' Untranslated Regions - genetics | Male | MicroRNAs - biosynthesis | Fibroblasts - pathology | Tissue Inhibitor of Metalloproteinase-1 - genetics | Proteolysis | Adaptor Proteins, Signal Transducing - genetics | Dermis - pathology | Female | Adaptor Proteins, Signal Transducing - biosynthesis | MicroRNAs - genetics | HeLa Cells | Fibroblasts - metabolism | Protectors | Control methods | Pathogenesis | Matrix metalloproteinase | Kinases | Tissue inhibitor of metalloproteinase 1 | Western blotting | Proteins | Connective tissues | Immunology | Transfection | Rodents | Fibroblasts | Skin diseases | Extracellular matrix | Growth factors | Enzyme-linked immunosorbent assay | Interstitial collagenase | Binding | Secretion | Organs | Blocking | Pharmacology | Gene expression | Medicine | 3' Untranslated regions | Biopsy | Systemic sclerosis | Collagen | Fibrosis | Transduction | Genetic engineering | Skin | Binding sites
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2014, Volume 73, Issue Suppl 1, pp. A47 - A48
Background and Objectives Systemic sclerosis (SSc) is an autoimmune connective tissue disease characterised by fibrosis of skin and internal organs via... 
Journal Article
Cells, ISSN 2073-4409, 08/2019, Volume 8, Issue 9, p. 953
Rheumatoid arthritis (RA) is a long-term autoimmune disease of unknown etiology that leads to progressive joint destruction and ultimately to disability. RA... 
DNA methylation | autoimmunity | rheumatoid arthritis | biomarkers | therapy | epigenetics
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2017, Volume 76, Issue Suppl 1, pp. A36 - A36
BackgroundMonocytes play an important role in autoimmune disease including rheumatoid arthritis (RA) or systemic sclerosis (SSc). Monocytes are the first... 
Journal Article
European Journal of Clinical Investigation, ISSN 0014-2972, 08/2017, Volume 47, Issue 8, pp. 555 - 564
Background Systemic sclerosis (SSc) is a chronic autoimmune disease characterised by tissue fibrosis and immune abnormalities. Recent evidence suggests that... 
monocytes | systemic sclerosis | RNA | inflammation | micro | Epigenetics | fibrosis | microRNA | MEDICINE, RESEARCH & EXPERIMENTAL | TIMP-1 | PROTEIN | MEDICINE, GENERAL & INTERNAL | SCLERODERMA | MMP-1 | PATHWAY | GENE-EXPRESSION | FRA-2 | SKIN | Leukocytes, Mononuclear - metabolism | Reactive Oxygen Species - metabolism | Humans | Middle Aged | Oxidative Stress - physiology | Male | MicroRNAs - metabolism | Peptides, Cyclic - pharmacology | Case-Control Studies | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Scleroderma, Systemic - etiology | Toll-Like Receptor 8 - antagonists & inhibitors | Transfection | Fos-Related Antigen-2 - metabolism | Aged, 80 and over | Adult | Female | Interleukin-8 - metabolism | Biomarkers - metabolism | Adenosine - pharmacology | Adenosine - analogs & derivatives | Histone Deacetylase Inhibitors - pharmacology | Aged | Tissue Inhibitor of Metalloproteinase-1 - secretion | Matrix Metalloproteinases - metabolism | MicroRNAs - physiology | Histones | Epigenetic inheritance | MicroRNA | Methyltransferases | Systemic scleroderma | Scleroderma (Disease) | Reactive oxygen species | Transcription factors | Pathogenesis | Abnormalities | Activator protein 1 | MiRNA | Superoxide dismutase | Stimulation | Gene expression | Tissue inhibitor of metalloproteinase 1 | Ribonucleic acid--RNA | Monocytes | Inhibitors | 3' Untranslated regions | Systemic sclerosis | MicroRNAs | Fibrosis | Peripheral blood | Biomarkers | Histone methyltransferase | Skin | Bioindicators | Interleukin 8
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 08/2013, Volume 72, Issue 8, pp. 1382 - 1389
Journal Article