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Journal of the American Society of Nephrology, ISSN 1046-6673, 01/2016, Volume 27, Issue 1, pp. 120 - 131
Journal Article
Blood, ISSN 0006-4971, 09/2008, Volume 112, Issue 5, pp. 1696 - 1703
Abstract Second messenger-mediated inside-out activation of integrin αIIbβ3 is a key step in platelet aggregation. We recently showed strongly impaired but not... 
Hemostasis, Thrombosis, and Vascular Biology
Journal Article
Blood, ISSN 0006-4971, 02/2013, Volume 121, Issue 6, pp. 1008 - 1015
The majority of peripheral serotonin is stored in platelets, which secrete it on activation. Serotonin releases Weibel-Palade bodies (WPBs) and we asked... 
PULMONARY-HYPERTENSION | PERMEABILITY | 5-HYDROXYTRYPTAMINE | ENDOTHELIAL-CELLS | MAST-CELLS | P-SELECTIN | RECEPTOR | SMOOTH-MUSCLE-CELLS | HEMATOLOGY | VON-WILLEBRAND-FACTOR | SELECTIN-DEFICIENT MICE | Blood Platelets - immunology | Endothelium, Vascular - drug effects | Male | Shock, Septic - immunology | Lipopolysaccharides | Serotonin - blood | Inflammation - metabolism | L-Selectin - immunology | Leukocytosis - metabolism | Weibel-Palade Bodies - metabolism | Chemotaxis - immunology | Neutrophils - metabolism | Serotonin - immunology | Serotonin Uptake Inhibitors - immunology | Endothelium, Vascular - immunology | Neutrophil Infiltration - immunology | Fluoxetine - pharmacology | Acute Disease | Neutrophils - drug effects | Leukocytosis - immunology | Chemotaxis - drug effects | Mice, Knockout | Blood Platelets - metabolism | Endothelium, Vascular - metabolism | Mice | Serotonin Uptake Inhibitors - pharmacology | Leukocyte Rolling - drug effects | Weibel-Palade Bodies - immunology | Histamine - immunology | L-Selectin - metabolism | Flow Cytometry | Tryptophan Hydroxylase - deficiency | Blood Platelets - drug effects | Fluoxetine - immunology | Shock, Septic - genetics | Leukocyte Rolling - genetics | Histamine - pharmacology | Shock, Septic - chemically induced | Mice, Inbred C57BL | Kaplan-Meier Estimate | Neutrophils - immunology | Inflammation - immunology | Leukocyte Rolling - immunology | Tryptophan Hydroxylase - genetics | Weibel-Palade Bodies - drug effects | Animals | Serotonin - metabolism | Inflammation - genetics | Leukocytosis - genetics | Phagocytes, Granulocytes, and Myelopoiesis | Platelets and Thrombopoiesis
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2006, Volume 103, Issue 45, pp. 16900 - 16905
GPIbα binding to von Willebrand factor (VWF) exposed at a site of vascular injury is thought to be the first step in the formation of a hemostatic plug.... 
Receptors | Arterioles | Blood vessels | Antibodies | Ligands | Platelets | Thrombosis | Adhesion | Blood | Integrins | BETA-3-INTEGRIN-DEFICIENT MICE | MULTIDISCIPLINARY SCIENCES | FACTOR-VIII | MONOCLONAL-ANTIBODY | adhesion | HIGH-SHEAR | IX-V COMPLEX | INTEGRIN MAC-1 | platelets | GLYCOPROTEIN IB-ALPHA | BERNARD-SOULIER-SYNDROME | P-SELECTIN | INJURED ARTERIOLES | Biological Sciences
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 21, pp. 37 - 37
Abstract Abstract 37 Transfusion-related acute lung injury (TRALI) is a serious complication of blood transfusion occurring within 6 hours of transfusion. It... 
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2017, Volume 12, Issue 12, p. e0188341
Journal Article
Blood, ISSN 0006-4971, 11/2010, Volume 116, Issue 21, pp. 2102 - 2102
Abstract Abstract 2102 Aberrant blood brain barrier (BBB) permeability is a hallmark pathology in many diseases of the central nervous system (CNS) including... 
Journal Article
Blood, ISSN 0006-4971, 05/2008, Volume 111, Issue 10, pp. 4958 - 4964
Journal Article
Journal Article
Cancer Research, ISSN 0008-5472, 08/2008, Volume 68, Issue 16, pp. 6851 - 6858
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 08/2010, Volume 88, Issue 2, pp. 313 - 319
Chemotaxis and integrin activation are essential processes for neutrophil transmigration in response to injury. CalDAG-GEFI plays a key role in the activation... 
Journal Article