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Journal of Clinical Oncology, ISSN 0732-183X, 05/2019, Volume 37, Issue 15_suppl, pp. e14160 - e14160
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 05/2018, Volume 36, Issue 15_suppl, pp. TPS4152 - TPS4152
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 02/2018, Volume 36, Issue 4_suppl, pp. 447 - 447
447 Background: BTC are aggressive tumors with limited treatment options and poor overall survival. Aberrant FGFR signaling has been implicated in BTC... 
Journal Article
JAMA Pediatrics, ISSN 2168-6203, 11/2015, Volume 169, Issue 11, p. 996
  Racial disparities in use of analgesia in emergency departments have been previously documented. Further work to understand the causes of these disparities... 
Pediatrics | Racial differences | Appendicitis | Pain management | Emergency medical care
Journal Article
Investigational New Drugs, ISSN 0167-6997, 2/2017, Volume 35, Issue 1, pp. 68 - 78
Background HER3/EGFR heterodimers have been implicated as a mode of resistance to EGFR-directed therapies. Methods This Phase 1 trial assessed the... 
Seribantumab | Medicine & Public Health | Oncology | Pharmacology/Toxicology | Cetuximab | EGFR | HER3 | TARGETED THERAPY | PLUS CETUXIMAB | ACQUIRED-RESISTANCE | RECEPTOR | ANTITUMOR-ACTIVITY | METASTATIC COLORECTAL-CANCER | TYROSINE KINASE INHIBITORS | LUNG-CANCER | ONCOLOGY | SQUAMOUS-CELL CARCINOMA | PHARMACOLOGY & PHARMACY | Receptor, Epidermal Growth Factor - genetics | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antineoplastic Combined Chemotherapy Protocols - pharmacokinetics | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Antineoplastic Agents - therapeutic use | Cetuximab - therapeutic use | Antineoplastic Combined Chemotherapy Protocols - pharmacology | Cetuximab - adverse effects | Young Adult | Antineoplastic Agents - adverse effects | Receptor, ErbB-3 - immunology | Aged, 80 and over | Adult | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Camptothecin - analogs & derivatives | Camptothecin - adverse effects | Camptothecin - therapeutic use | Antibodies, Monoclonal - pharmacokinetics | Cetuximab - pharmacology | Treatment Outcome | Maximum Tolerated Dose | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Aged | Camptothecin - pharmacology | Care and treatment | Drug therapy, Combination | Patient outcomes | Methods | Cancer | Index Medicus
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 2019, Volume 25, Issue 9, pp. 2699 - 2707
Purpose: To investigate tolerability, efficacy, and pharmacokinetics/pharmacodynamics of Debio 1347, a selective FGFR inhibitor. Patients and Methods: This was... 
CANCER-CELLS | FREQUENT | ONCOLOGY | FIBROBLAST | SENSITIVITY | MUTATIONS | RECEPTORS | CELL-CARCINOMA
Journal Article
Radiation Oncology, ISSN 1748-717X, 12/2017, Volume 12, Issue 1, pp. 201 - 7
Background: Our previous studies showed that vasoconstrictor applied topically to rat skin minutes before irradiation completely prevented radiodermatitis.... 
Phase IIa clinical trial | ROS | MANAGEMENT | TREATMENT INTERRUPTIONS | IRRADIATION | PROPHYLAXIS | IMPACT | THERAPY | ONCOLOGY | RADIOTHERAPY | OF-THE-LITERATURE | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | SKIN REACTIONS | Lumpectomy | Cancer patients | Care and treatment | Analysis | Radiation | Carcinoma, Ductal | Skin | Inflammation | Research | Radiotherapy | Dermatitis | Cancer
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 05/2015, Volume 372, Issue 20, pp. 1909 - 1919
Journal Article
Ophthalmology, ISSN 0161-6420, 2018, Volume 125, Issue 12, pp. 1913 - 1928
PURPOSE: To analyze the prevalence, incidence, and clinical characteristics of eyes with geographic atrophy (GA) in age-related macular degeneration (AMD),... 
PHOTOGRAPHS | DEFINITION | EYE DISEASE | COMPLEMENT | INFLAMMATION | GROWTH | FUNDUS AUTOFLUORESCENCE IMAGES | OPHTHALMOLOGY | END-POINTS | ASSOCIATION | APOLIPOPROTEIN-E
Journal Article
Nature, ISSN 0028-0836, 07/2017, Volume 547, Issue 7664, pp. 453 - 457
Plasticity of the cell state has been proposed to drive resistance to multiple classes of cancer therapies, thereby limiting their effectiveness(1-4). A... 
EPITHELIAL-MESENCHYMAL TRANSITION | METABOLISM | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | HUMAN-MELANOMA CELLS | SENSITIVITY | DEATH | INHIBITOR | EXPRESSION | SIGNATURE | REVEALS | Prostatic Neoplasms - metabolism | Cadherins - metabolism | Humans | Mesoderm - drug effects | Melanoma - enzymology | Male | Lipid Peroxides - metabolism | Zinc Finger E-box-Binding Homeobox 1 - genetics | Neoplasms - genetics | Mesoderm - enzymology | Cell Death | Epithelial-Mesenchymal Transition | Lipid Peroxidation - drug effects | Cell Transdifferentiation | Prostatic Neoplasms - drug therapy | Melanoma - metabolism | Glutathione Peroxidase - metabolism | Prostatic Neoplasms - pathology | Reproducibility of Results | Neoplasms - enzymology | Melanoma - pathology | Iron - metabolism | Neoplasms - drug therapy | Cell Lineage | Drug Resistance, Neoplasm - genetics | Proto-Oncogene Proteins B-raf - genetics | Melanoma - drug therapy | Proteomics | Cell Line, Tumor | Prostatic Neoplasms - enzymology | Mesoderm - metabolism | Neoplasms - pathology | Mesoderm - pathology | Peroxidase | Research | Chemical properties | Chemical synthesis | Analysis | Cancer cells | Therapy | Biotechnology | Carcinoma | Mesenchyme | Genes | Lipid peroxidation | Lipids | Iron | Genomes | Phospholipids | Kinases | Cancer therapies | Proteins | Organoids | Dissipation | Peroxides | Lipid metabolism | Glutathione | Transfer RNA | Peroxidation | Glutathione peroxidase | Enzymes | Mortality | Melanoma | Selenocysteine | Tumor cell lines | Metabolism | Substrates | Cell death | Lipoxygenase | Prostate cancer | Prostate | Tumors | Apoptosis | Cancer | Index Medicus
Journal Article
Ophthalmology, ISSN 0161-6420, 2019, Volume 126, Issue 2, pp. 261 - 273
PURPOSE: To investigate the natural history and genetic associations of drusenoid pigment epithelial detachment (DPED) associated with age-related macular... 
ARMS2 | EYE DISEASE | EVOLUTION | OPHTHALMOLOGY | CLASSIFICATION | RISK | POLYMORPHISM | VARIANT | GEOGRAPHIC ATROPHY
Journal Article