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by Birney, Ewan and Stamatoyannopoulos, John A and Dutta, Anindya and Guigó, Roderic and Gingeras, Thomas R and Margulies, Elliott H and Weng, Zhiping and Snyder, Michael and Dermitzakis, Emmanouil T and Thurman, Robert E and Kuehn, Michael S and Taylor, Christopher M and Neph, Shane and Koch, Christoph M and Asthana, Saurabh and Malhotra, Ankit and Adzhubei, Ivan and Greenbaum, Jason A and Andrews, Robert M and Flicek, Paul and Boyle, Patrick J and Cao, Hua and Carter, Nigel P and Clelland, Gayle K and Davis, Sean and Day, Nathan and Dhami, Pawandeep and Dillon, Shane C and Dorschner, Michael O and Fiegler, Heike and Giresi, Paul G and Goldy, Jeff and Hawrylycz, Michael and Haydock, Andrew and Humbert, Richard and James, Keith D and Johnson, Brett E and Johnson, Ericka M and Frum, Tristan T and Rosenzweig, Elizabeth R and Karnani, Neerja and Lee, Kirsten and Lefebvre, Gregory C and Navas, Patrick A and Neri, Fidencio and Parker, Stephen C. J and Sabo, Peter J and Sandstrom, Richard and Shafer, Anthony and Vetrie, David and Weaver, Molly and Wilcox, Sarah and Yu, Man and Collins, Francis S and Dekker, Job and Lieb, Jason D and Tullius, Thomas D and Crawford, Gregory E and Sunyaev, Shamil and Noble, William S and Dunham, Ian and Denoeud, France and Reymond, Alexandre and Kapranov, Philipp and Rozowsky, Joel and Zheng, Deyou and Castelo, Robert and Frankish, Adam and Harrow, Jennifer and Ghosh, Srinka and Sandelin, Albin and Hofacker, Ivo L and Baertsch, Robert and Keefe, Damian and Dike, Sujit and Cheng, Jill and Hirsch, Heather A and Sekinger, Edward A and Lagarde, Julien and Abril, Josep F and Shahab, Atif and Flamm, Christoph and Fried, Claudia and Hackermüller, Jörg and Hertel, Jana and Lindemeyer, Manja and Missal, Kristin and Tanzer, Andrea and Washietl, Stefan and Korbel, Jan and Emanuelsson, Olof and Pedersen, Jakob S and Holroyd, Nancy and Taylor, Ruth and Swarbreck, David and Matthews, Nicholas and Dickson, Mark C and Thomas, Daryl J and Weirauch, Matthew T and Gilbert, James and ... and ENCODE Project Consortium and Baylor College of Medicine Human Genome Sequencing Center and Washington University Genome Sequencing Center and Children's Hospital Oakland Research Institute and NISC Comparative Sequencing Program and Broad Institute and The ENCODE Project Consortium
Nature, ISSN 0028-0836, 06/2007, Volume 447, Issue 7146, pp. 799 - 816
Journal Article
Stem Cells, ISSN 1066-5099, 05/2008, Volume 26, Issue 5, pp. 1174 - 1185
Activation of Hox gene clusters is an early event in embryonic development since individual members play important roles in patterning of the body axis. Their... 
Journal Article
Genome Research, ISSN 1088-9051, 06/2007, Volume 17, Issue 6, pp. 708 - 719
Butyrate is a histone deacetylase inhibitor (HDACi) with anti-neoplastic properties, which theoretically reactivates epigenetically silenced genes by... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | PERICENTRIC HETEROCHROMATIN | TRICHOSTATIN-A | BREAST-CANCER CELLS | ACETYLTRANSFERASE ACTIVITY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | CORE PROMOTER | DEACETYLASE INHIBITORS | SODIUM-BUTYRATE | IN-VIVO | GENETICS & HEREDITY | HEPG2 CELLS | GENOME-WIDE | Oligonucleotide Array Sequence Analysis | Butyrates - pharmacology | Humans | Enzyme Inhibitors - pharmacology | Histone Deacetylases - metabolism | Gene Expression Profiling | Neoplasm Proteins - metabolism | Colonic Neoplasms - metabolism | Acetylation - drug effects | Adenocarcinoma - metabolism | Protein Processing, Post-Translational - drug effects | Cell Line, Tumor | Histone Deacetylase Inhibitors | Gene Expression Regulation, Neoplastic - drug effects | Histones - metabolism | Histones | Gene silencing | Genetic transcription | Genetic regulation | Analysis | Biological Sciences | Acetylation/drug effects | Medical and Health Sciences | Butyrates/pharmacology | Medicin och hälsovetenskap | Gene Expression Regulation; Neoplastic/drug effects | Protein Processing; Post-Translational/drug effects | Biology | MEDICINE | Enzyme Inhibitors/pharmacology | Histones/metabolism | Histone Deacetylases/antagonists & inhibitors/metabolism | Naturvetenskap | MEDICIN | Biologiska vetenskaper | Cell Line; Tumor | Colonic Neoplasms/metabolism | Adenocarcinoma/metabolism | Biologi | Natural Sciences | Neoplasm Proteins/metabolism
Journal Article
Genome Research, ISSN 1088-9051, 06/2007, Volume 17, Issue 6, pp. 708 - 719
Butyrate is a histone deacetylase inhibitor (HDACi) with anti-neoplastic properties, which theoretically reactivates epigenetically silenced genes by... 
Journal Article
Genome Research, ISSN 1088-9051, 06/2007, Volume 17, Issue 6, pp. 691 - 707
We generated high-resolution maps of histone H3 lysine 9/14 acetylation (H3ac), histone H4 lysine 5/8/12/16 acetylation (H4ac), and histone H3 at lysine 4... 
Journal Article
Stem Cells, ISSN 1066-5099, 05/2008, Volume 26, Issue 5, pp. 1174 - 1185
Journal Article
by Wong, Hanna and Wong, Danny J.N and Wong, Rachel and Wong, D.J.N and Wong, Gabriela and Harris, Meredith and Harris, Stephen and Harris, Catherine and Harris, Rebecca and Harris, Steve K and Harris, S.K and Moonesinghe, S. Ramani and Moonesinghe, S.R and Bedford, James and Boney, Oliver and Chazapis, Maria and Drake, Sharon and Drake, Jeremy and Farmer, Nicola and Farmer, Laura and Gilhooly, David and Goodwin, Naomi and Goodwin, James and Lourtie, Jose and Wagstaff, Duncan and Wagstaff, Adrian and Grocott, Jeanette and Grocott, Mike and Sneyd, Robert and Batchelor, Anna and Brett, Stephen and Brett, Michael and Plowright, Catherine and Shrestha, Suman and Shawyer, Richard and Ahmed, Dabeeruddeen and Ahmed, Raheel and Ahmed, Mohamed and Ahmed, Sameer and Ahmed, Muneeba and Ahmed, Sajjad and Ahmed, Shafi and Ahmed, Zaid and Khondoker, Mizan and Nathanson, Mike and Cripps, Paul and Research & Audit Federation of Trainees (RAFT) and Anaesthetic Audit and Research Matrix of Yorkshire (AARMY) and Intensive Care & Anaesthesia Research Network of North East Trainees (INCARNNET) and Merseyside Anaesthetic Group for Improving Quality (MAGIQ) and Midlands East Research by Critical Care and Anaesthetic Trainees (MERCAT) and North West Research and Audit Group (NWRAG) and Oxford Critical Care Anaesthetic Research Enterprise (OxCCARE) and Pan-London Peri-operative Audit & Research Network (PLAN) and Scottish East Quality Improvement & Research Academy (SEQuoIA) and SESSA Quality Improvement and Research Network (SQUARES) and Severn Trainees Anaesthetic Research (STAR) and South West Anaesthetic Research Matrix (SWARM) and South Yorkshire Hospitals Audit and Research Collaboration (SHARC) and Southcoast Peri-operative Audit and Research Collaboration (SPARC) and Welsh Anaesthetic Audit Research & Engagement Network (WAAREN) and West Midlands Trainee Research Anaesthesia & Intensive Care Network (WMTRAIN) and Rawat, Shilpa and Sathe, Sonia and Campbell, Matthew and Campbell, Bridget and Campbell, Debbie and Campbell, Alison and Campbell, Marta and Campbell, Euan and Campbell, Rachel and Campbell, Brian and Anandarajah, Janakan and Ball, Nicola and Bandara, Lalindra and Barnes, Dennis and Barnes, Elizabeth and Barnes, Veronica and Chapman, Susie and Chapman, Andy and Chapman, Roddy and Chapman, Catherine and Connor, Lynda and Cook, Amanda and Cook, Prof Tim and Cook, Angela and Ebejer, Amanda and Evans, Sandra and Evans, Alison and Evans, Samantha and Evans, Peter and Evans, Hywel and Evans, Gail and Evans, James and Evans, Jackie and Evans, Lucy and Evans, Elizabeth and Gallagher, Maire and Gallagher, Kate and Gallagher, Susan and ... and SNAP-2 EPICCS Collaborators and NHS Shetland and University Hospital of North Midlands NHS Trust and Gateshead Health NHS Foundation Trust and St George's Healthcare NHS Trust and Cardiff and Vale University Health Board and South Eastern Health and Social Care Trust and Frimley Health NHS Foundation Trust and Cwm Taf University Health Board and Trainee Research Networks and Colchester Hospital University NHS Foundation Trust and Barts Health NHS Trust and Oxford University Hospitals NHS Foundation Trust and Royal Bournemouth & Christchurch Hospitals NHS Foundation Trust and Royal Cornwall Hospitals NHS Trust and Isle of Wight NHS Trust and County Durham and Darlington NHS Foundation Trust and Sheffield Teaching Hospitals NHS Foundation Trust and University Hospitals of Morecambe Bay NHS Foundation Trust and Northern Health and Social Care Trust and Surrey and Sussex Healthcare NHS Trust and Chelsea and Westminster Hospital NHS Foundation Trust and Croydon Health Services NHS Trust and Airedale NHS Foundation Trust and Weston Area Health NHS Trust and Northern Lincolnshire and Goole Hospitals NHS Foundation Trust and Royal Wolverhampton Hospitals NHS Trust and Abertawe Bro Morgannwg University Health Board and Northumbria Healthcare NHS Foundation Trust and Brighton and Sussex University Hospitals NHS Trust and NHS Lothian and Lewisham and Greenwich NHS Trust and Homerton University Hospital NHS Foundation Trust and East Kent Hospitals University NHS Foundation Trust and Milton Keynes University Hospital NHS Foundation Trust and Great Western Hospitals NHS Foundation Trust and Lancashire Teaching Hospitals NHS Foundation Trust and City Hospitals Sunderland NHS Foundation Trust and Northampton General Hospital NHS Trust and North Tees and Hartlepool NHS Trust and Hywel Dda Health Board and Royal Devon and Exeter NHS Foundation Trust and Dorset County Hospital NHS Foundation Trust and Dudley Group NHS Foundation Trust and Liverpool Women's NHS Foundation Trust and Bedford Hospital NHS Trust and Royal National Orthopaedic Hospital NHS Trust and Medway NHS Foundation Trust and University Hospitals Birmingham NHS Foundation Trust and Gloucestershire Hospitals NHS Foundation Trust and Pennine Acute NHS Trust and Northern Devon Healthcare NHS Trust and Betsi Cadwaladr University Health Board and Epsom and St Helier University Hospitals NHS Trust and Ipswich Hospital NHS Trust and Chesterfield Royal Hospital NHS Foundation Trust and NHS Greater Glasgow & Clyde and Western Sussex Hospitals NHS Foundation Trust and NHS Lanarkshire and Blackpool Teaching Hospitals NHS Foundation Trust and Central Manchester University Hospitals NHS Foundation Trust and Buckinghamshire Healthcare NHS Trust and Hillingdon Hospitals NHS Foundation Trust and Salford Royal NHS Foundation Trust and Tameside Hospital NHS Foundation Trust and Walsall Healthcare NHS Trust and York Teaching Hospital NHS Foundation Trust and Burton Hospitals NHS Foundation Trust and Mid Essex Hospital Services NHS Trust and Birmingham Women's NHS Foundation Trust and Dartford and Gravesham NHS Trust and Kingston Hospital NHS Foundation Trust and NHS Tayside and Salisbury NHS Foundation Trust and Study Steering Group and Royal Berkshire NHS Foundation Trust and Mid Yorkshire Hospitals NHS Trust and Robert Jones and Agnes Hunt Orthopaedic Hospital Foundation Trust and East Sussex Healthcare NHS Trust and King's College Hospital NHS Foundation Trust and Aintree University Hospitals NHS Foundation Trust and NHS Highland and West Herts Hospitals NHS Trust and Worcestershire Acute Hospitals NHS Trust and Guy's and St Thomas' NHS Foundation Trust and Hull and East Yorkshire Hospitals NHS Trust and Shrewsbury and Telford Hospital NHS Trust and Hampshire Hospitals NHS Foundation Trust and Torbay and South Devon NHS Foundation Trust and SNAP-2: EPICCS collaborators and Derby Hospitals NHS Foundation Trust and North West Anglia NHS Foundation Trust and Plymouth Hospitals NHS Trust and Wye Valley NHS Trust and Leeds Teaching Hospitals NHS Trust and NHS Fife and South Tees Hospitals NHS Foundation Trust and University Hospitals Coventry and Warwickshire NHS Trust and Christie Hospital NHS Foundation Trust and Royal Free London NHS Foundation Trust and Wrightington, Wigan and Leigh NHS Foundation Trust and United Lincolnshire Hospitals NHS Trust and Bradford Teaching Hospitals NHS Foundation Trust and Newcastle upon Tyne Hospitals NHS Foundation Trust and Queen Elizabeth Hospital NHS Foundation Trust and Royal Marsden NHS Foundation Trust and Whittington Hospital NHS Trust and Portsmouth Hospitals NHS Trust and University College London Hospitals NHS Foundation Trust and University Hospitals of Leicester NHS Trust and Ashford & St Peters NHS Foundation Trust and Royal United Hospitals Bath NHS Trust and Royal Surrey County Hospital NHS Foundation Trust and East and North Hertfordshire NHS Trust and Kettering General Hospital NHS Foundation Trust and Rotherham NHS Foundation Trust and St Helens and Knowsley Teaching Hospitals NHS Trust and University Hospital Southampton NHS Foundation Trust and Health Services Research Centre, National Institute of Academic Anaesthesia and East Lancashire Hospitals NHS Trust and Warrington & Halton Hospitals NHS Foundation Trust and Calderdale and Huddersfield NHS Foundation Trust and Countess of Chester NHS Foundation Trust and University Hospitals Bristol NHS Foundation Trust and Harrogate and District NHS Foundation Trust and NHS Scotland Special Board and South Tyneside NHS Foundation Trust and Barnsley Hospital NHS Foundation Trust and Sandwell and West Birmingham Hospitals NHS Trust and North Cumbria University Hospitals NHS Trust and Aneurin Bevan Health Board and Barking, Havering and Redbridge University Hospitals NHS Trust and Bolton Hospital NHS Foundation Trust and Luton and Dunstable University Hospital NHS Foundation Trust and NHS Ayrshire & Arran and Queen Victoria Hospital NHS Foundation Trust and University Hospital of South Manchester NHS Foundation Trust and Wirral University Teaching Hospital NHS Foundation Trust and James Paget University Hospitals NHS Foundation Trust and North Bristol NHS Trust and Western Health and Social Care Trust and NHS Dumfries & Galloway and Imperial College Healthcare NHS Trust and South Warwickshire NHS Foundation Trust and Princess Alexandra Hospital NHS Trust and Poole Hospital NHS Foundation Trust and North Middlesex University Hospital NHS Trust and Belfast Health and Social Care Trust and Mid Cheshire Hospitals NHS Foundation Trust and Royal Orthopaedic Hospital NHS Foundation Trust and Taunton and Somerset NHS Foundation Trust and Yeovil District Hospital NHS Foundation Trust and Cambridge University Hospitals NHS Foundation Trust and Heart Of England NHS Foundation Trust and Net Solving Limited and Papworth Hospital NHS Foundation Trust and Basildon and Thurrock University Hospitals NHS Foundation Trust and Norfolk and Norwich University Hospitals NHS Foundation Trust and Southport and Ormskirk Hospital NHS Trust and Stockport NHS Foundation Trust and Royal Liverpool and Broadgreen University Hospitals NHS Trust and Nottingham University Hospitals NHS Trust and West Suffolk NHS Foundation Trust and Doncaster and Bassetlaw Hospitals NHS Foundation Trust
British Journal of Anaesthesia, ISSN 0007-0912, 10/2018, Volume 121, Issue 4, pp. 730 - 738
Cancellation of planned surgery impacts substantially on patients and health systems. This study describes the incidence and reasons for cancellation of... 
operating room management | Health Services Research | medical resource utilisation | surgery | NEED | VALIDATION | ANESTHESIOLOGY | CRITICAL-CARE | CANCELLATIONS | ELECTIVE SURGERY
Journal Article