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1. Full Text Mild cognitive impairment due to Alzheimer disease in the community
by Petersen, Ronald C and Aisen, Paul and Boeve, Bradley F and Geda, Yonas E and Ivnik, Robert J and Knopman, David S and Mielke, Michelle and Pankratz, Vernon S and Roberts, Rosebud and Rocca, Walter A and Weigand, Stephen and Weiner, Michael and Wiste, Heather and Jack, Clifford R
Annals of Neurology, ISSN 0364-5134, 08/2013, Volume 74, Issue 2, pp. 199 - 208
Objective The newly proposed National Institute on Aging–Alzheimer's Association (NIA‐AA) criteria for mild cognitive impairment (MCI) due to Alzheimer disease... 
MCI | MRI | ATROPHY | ROCHESTER EPIDEMIOLOGY PROJECT | CLINICAL DEMENTIA | HIPPOCAMPAL | CSF BIOMARKERS | MEDICAL-RECORDS LINKAGE | HYPOTHETICAL MODEL | DYNAMIC BIOMARKERS | NEUROSCIENCES | CLINICAL NEUROLOGY | Residence Characteristics | Alzheimer Disease - complications | Cognitive Dysfunction - metabolism | Humans | Male | Random Allocation | Cognitive Dysfunction - etiology | Aging - pathology | Neuropsychological Tests | Amyloid - metabolism | Aged, 80 and over | Biomarkers | Female | Aged | Cognitive Dysfunction - diagnosis | Aging - metabolism | Alzheimers disease | Neurodegeneration
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2. Full Text TDP-43 is a key player in the clinical features associated with Alzheimer's disease
by Josephs, Keith A and Whitwell, Jennifer L and Weigand, Stephen D and Murray, Melissa E and Tosakulwong, Nirubol and Liesinger, Amanda M and Petrucelli, Leonard and Senjem, Matthew L and Knopman, David S and Boeve, Bradley F and Ivnik, Robert J and Smith, Glenn E and Jack Jr, Clifford R and Parisi, Joseph E and Petersen, Ronald C and Dickson, Dennis W
Acta Neuropathologica, ISSN 0001-6322, 2014, Volume 127, Issue 6, pp. 811 - 824
The aim of this study was to determine whether the TAR DNA-binding protein of 43 kDa (TDP-43) has any independent effect on the clinical and neuroimaging... 
APOE ε4 | Braak stage | Alzheimer disease | MRI | TDP-43 | Resilience | DEMENTIA | IMMUNOREACTIVITY | APOE epsilon 4 | PATHOLOGY | NEUROSCIENCES | CLINICAL NEUROLOGY | DEGENERATION | HIPPOCAMPAL SCLEROSIS | NEUROPATHOLOGICALLY DEFINED SUBTYPES | AGE | Immunohistochemistry | Severity of Illness Index | Memory Disorders - physiopathology | Alzheimer Disease - physiopathology | Apolipoprotein E4 - genetics | Memory Disorders - genetics | Brain - physiopathology | Humans | Middle Aged | Male | Alzheimer Disease - pathology | Atrophy | DNA-Binding Proteins - metabolism | Magnetic Resonance Imaging | Regression Analysis | Sclerosis - pathology | Aged, 80 and over | Brain - pathology | Cognition - physiology | Female | Aged | Alzheimer Disease - genetics | Alzheimer Disease - psychology | Memory Disorders - pathology | Diagnostic imaging | Apolipoproteins | Health aspects | Alzheimer's disease | DNA | Protein binding
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3. Full Text Preclinical Alzheimer's disease: a valid concept
by Jack, Clifford R
The Lancet Neurology, ISSN 1474-4422, 01/2020, Volume 19, Issue 1, pp. 31 - 31
CLINICAL NEUROLOGY
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4. Full Text FDG PET and MRI in Logopenic Primary Progressive Aphasia versus Dementia of the Alzheimer's Type
by Madhavan, Ajay and Whitwell, Jennifer L and Weigand, Stephen D and Duffy, Joseph R and Strand, Edythe A and Machulda, Mary M and Tosakulwong, Nirubol and Senjem, Matthew L and Gunter, Jeffrey L and Lowe, Val J and Petersen, Ronald C and Jack Jr, Clifford R and Josephs, Keith A
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e62471
Objectives: The logopenic variant of primary progressive aphasia is an atypical clinical variant of Alzheimer's disease which is typically characterized by... 
3 VARIANTS | DEFINED SUBTYPES | MULTIDISCIPLINARY SCIENCES | FRONTOTEMPORAL DEMENTIA | STRUCTURAL MRI | DISEASE | SEGMENTATION | PATHOLOGY | SPEECH | MILD COGNITIVE IMPAIRMENT | BRAIN | Diagnosis, Differential | Humans | Middle Aged | Image Interpretation, Computer-Assisted | Male | Positron-Emission Tomography | Alzheimer Disease - diagnosis | Aphasia, Primary Progressive - diagnosis | Magnetic Resonance Imaging | Aged, 80 and over | Brain - pathology | Female | Fluorodeoxyglucose F18 | Aged | Aphasia | PET imaging | Magnetic resonance imaging | Alzheimer's disease
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5. Full Text Amyloid PET and Changes in Clinical Management for Patients with Cognitive Impairment
by Jack, Clifford R and Petersen, Ronald C
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 04/2019, Volume 321, Issue 13, pp. 1258 - 1260
The article discusses the findings o9f a study to evaluate the association, if any, between amyloid Positron Emission Tomography (PET) and subsequent changes... 
PATHOLOGIES | DIAGNOSIS | TRIALS | MEDICINE, GENERAL & INTERNAL | NATIONAL INSTITUTE | DEMENTIA | TASK-FORCE | ALZHEIMERS-DISEASE | GUIDELINES | Usage | Care and treatment | Diagnosis | PET imaging | Dementia | Health care | Scanning | Medicare | Medical treatment | Cognitive ability | Positron emission | Government programs | Dementia disorders | Tomography | Amyloid | Diagnostic systems | Medicaid | Positron emission tomography
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6. Full Text A brief history of “Alzheimer disease”: Multiple meanings separated by a common name
by Knopman, David S and Petersen, Ronald C and Jack, Clifford R
Neurology, ISSN 0028-3878, 05/2019, Volume 92, Issue 22, pp. 1053 - 1059
The field of Alzheimer disease (AD) has a nosologic problemThe diagnostic label “Alzheimer disease” has several distinctive meanings. The term probable AD was... 
NATIONAL INSTITUTE | HIPPOCAMPAL SCLEROSIS | CLINICAL-DIAGNOSIS | AMYLOID-BETA | P-TAU | DIAGNOSTIC GUIDELINES | CSF T-TAU | MILD COGNITIVE IMPAIRMENT | CLINICAL NEUROLOGY | ASSOCIATION WORKGROUPS | NEUROPATHOLOGIC ASSESSMENT | Alzheimer Disease - diagnosis | Terminology as Topic | Alzheimer Disease - history | History, 21st Century | History, 20th Century | Humans
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7. Full Text Factors Associated With Meningioma Detected in a Population-Based Sample
by Cerhan, Jane H and Butts, Alissa M and Syrjanen, Jeremy A and Aakre, Jeremiah A and Brown, Paul D and Petersen, Ronald C and Jack, Clifford R and Roberts, Rosebud O
Mayo Clinic Proceedings, ISSN 0025-6196, 02/2019, Volume 94, Issue 2, pp. 254 - 261
To determine the frequency of incidental meningioma and identify associated factors in a population-based sample of participants who systematically underwent... 
TUMOR | MEDICINE, GENERAL & INTERNAL | RISK-FACTORS | CANCER | GLIOMA | BRAIN | Neuroimaging | Usage | Analysis | Diagnosis | Research | Meningioma | Prevalence studies (Epidemiology) | Nuclear magnetic resonance--NMR | Antiinflammatory agents | Brain tumors | Coronary artery | Central nervous system | Medical records | Population studies | Inflammation | Body mass index | Autopsy | Aging | Hormone replacement therapy | Blood pressure | Anxiety | Nonsteroidal anti-inflammatory drugs | Health risk assessment | Heart diseases | Cancer
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8. Full Text Cardiorespiratory Fitness and Brain Volumes
by Petersen, Ronald C and Joyner, Michael J and Jack, Clifford R
Mayo Clinic Proceedings, ISSN 0025-6196, 01/2020, Volume 95, Issue 1, pp. 6 - 8
MEDICINE, GENERAL & INTERNAL | RISK | EXERCISE | AGE
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9. Full Text Clinical and neuroimaging characteristics of clinically unclassifiable primary progressive aphasia
by Utianski, Rene L and Botha, Hugo and Martin, Peter R and Schwarz, Christopher G and Duffy, Joseph R and Clark, Heather M and Machulda, Mary M and Butts, Alissa M and Lowe, Val J and Jack, Clifford R and Senjem, Matthew L and Spychalla, Anthony J and Whitwell, Jennifer L and Josephs, Keith A
Brain and Language, ISSN 0093-934X, 10/2019, Volume 197, p. 104676
Many patients who meet core/root criteria for Primary Progressive Aphasia (PPA) are not classifiable as a recognized variant and are often excluded from... 
PET imaging | Primary progressive aphasia | Frontotemporal dementia | Hypometabolism | Amyloid imaging | CRITERIA | PPA | 3 VARIANTS | DIAGNOSIS | FORM | FRONTOTEMPORAL PATHOLOGY | ALZHEIMERS-DISEASE | AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY | CLASSIFICATION | APRAXIA | NEUROSCIENCES | PSYCHOLOGY, EXPERIMENTAL | LINGUISTICS | IQ-ADJUSTED NORMS | Brain | Medical imaging | Age of onset | Magnetic resonance imaging (MRI) | Aphasia | Sound duration (Phonetics) | Patients | Neuroimaging techniques
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10. Full Text Biomarker modeling of alzheimer's disease
by Jack, Clifford R and Holtzman, David M
Neuron, ISSN 0896-6273, 12/2013, Volume 80, Issue 6, pp. 1347 - 1358
Alzheimer's disease (AD) is a slowly progressing disorder in which pathophysiological abnormalities, detectable invivo by biomarkers, precede overt clinical... 
NATIONAL INSTITUTE | POSITRON-EMISSION-TOMOGRAPHY | AMYLOID-BETA DEPOSITION | A-BETA | CEREBROSPINAL-FLUID A-BETA | MILD COGNITIVE IMPAIRMENT | NEUROSCIENCES | PITTSBURGH COMPOUND-B | GENOME-WIDE ASSOCIATION | VOXEL-BASED MORPHOMETRY | APOLIPOPROTEIN-E | Biomarkers - metabolism | Neuroimaging | Peptide Fragments - metabolism | Peptide Fragments - cerebrospinal fluid | Humans | tau Proteins - metabolism | tau Proteins - cerebrospinal fluid | Aging - cerebrospinal fluid | Alzheimer Disease - cerebrospinal fluid | Plaque, Amyloid - cerebrospinal fluid | Aging - pathology | Alzheimer Disease - pathology | Alzheimer Disease - diagnosis | Brain - metabolism | Time Factors | Models, Biological | Alzheimer Disease - metabolism | Amyloid beta-Peptides - metabolism | Amyloid beta-Peptides - cerebrospinal fluid | Brain - pathology | Plaque, Amyloid - metabolism | Biomarkers - cerebrospinal fluid | Aging - metabolism | Alzheimer's disease | Models | Amyloid beta-protein | Pathology | Mutation | Alzheimers disease | Neurodegeneration | Rodents | Genes | amyloid imaging | MRI AND Alzheimer's | Alzheimer's modeling | PET AND Alzheimer's | Alzheimer's biomarkers | Alzheimer's imaging
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11. Full Text Regional multimodal relationships between tau, hypometabolism, atrophy, and fractional anisotropy in atypical Alzheimer's disease
by Sintini, Irene and Schwarz, Christopher G and Martin, Peter R and Graff‐Radford, Jonathan and Machulda, Mary M and Senjem, Matthew L and Reid, Robert I and Spychalla, Anthony J and Drubach, Daniel A and Lowe, Val J and Jack, Clifford R and Josephs, Keith A and Whitwell, Jennifer L
Human Brain Mapping, ISSN 1065-9471, 04/2019, Volume 40, Issue 5, pp. 1618 - 1631
Alzheimer's disease (AD) can present with atypical clinical forms where the prominent domain of deficit is not memory, that is, atypical AD. Atypical AD... 
atypical Alzheimer's disease | MRI | DTI | FDG | tau | multimodal imaging | multivariate analysis | WHITE-MATTER | VARIANTS | VOLUME | PATTERNS | NEUROSCIENCES | NEUROIMAGING | GLUCOSE-METABOLISM | REGISTRATION | BURDEN | RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING | PET | Pets | PET imaging | Anisotropy | Alzheimer's disease | Neuroimaging | Radiation | Substantia grisea | Atrophy | Neurodegeneration | Tomography | Thalamus | Cingulum | Degeneration | Hypometabolism | Medical imaging | Neurodegenerative diseases | Cortex | Positron emission | Fluorine isotopes | Metabolism | Substantia alba | Patients | Corpus callosum | Neurology | Tensors | Magnetic resonance imaging | Tau protein | Correlation analysis | Neural networks | Alzheimers disease | Positron emission tomography
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12. Full Text Longitudinal tau-PET uptake and atrophy in atypical Alzheimer's disease
by Sintini, Irene and Martin, Peter R and Graff-Radford, Jonathan and Senjem, Matthew L and Schwarz, Christopher G and Machulda, Mary M and Spychalla, Anthony J and Drubach, Daniel A and Knopman, David S and Petersen, Ronald C and Lowe, Val J and Jack, Clifford R and Josephs, Keith A and Whitwell, Jennifer L
NeuroImage: Clinical, ISSN 2213-1582, 2019, Volume 23, p. 101823
The aims of this study were: to examine regional rates of change in tau-PET uptake and grey matter volume in atypical Alzheimer's disease (AD); to investigate... 
Atrophy | Longitudinal tau-PET | Multimodal imaging | Atypical AD | PATTERNS | NEURODEGENERATION | ASSOCIATION GUIDELINES | AMYLOID LOAD | HYPOTHETICAL MODEL | NEUROIMAGING | NEUROPATHOLOGIC ASSESSMENT | BETA | NATIONAL INSTITUTE | IN-VIVO | PROPAGATION
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13. Full Text Multimodal neuroimaging relationships in progressive supranuclear palsy
by Sintini, Irene and Schwarz, Christopher G and Senjem, Matthew L and Reid, Robert I and Botha, Hugo and Ali, Farwa and Ahlskog, J. Eric and Jack, Clifford R and Lowe, Val J and Josephs, Keith A and Whitwell, Jennifer L
Parkinsonism and Related Disorders, ISSN 1353-8020, 09/2019, Volume 66, pp. 56 - 61
Progressive supranuclear palsy is characterized primarily by 4R tau inclusions, atrophy in the brainstem and basal ganglia, and neurodegeneration along the... 
DTI | Multimodal imaging | PSP | MRI | Tau-PET | DIAGNOSIS | ALZHEIMERS-DISEASE | CLINICAL NEUROLOGY | VOXEL-BASED MORPHOMETRY | DEGENERATION | POSITRON-EMISSION-TOMOGRAPHY | TRACER | BINDING | Pets | Diagnostic imaging | Progressive supranuclear palsy | Anisotropy
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14. Design mix manual for concrete construction
by Long, Leslie D
1982, ISBN 9780070386839, xiv, 386, [1]
Mixing | Concrete
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15. Full Text White Matter Integrity Determined With Diffusion Tensor Imaging in Older Adults Without Dementia: Influence of Amyloid Load and Neurodegeneration
by Kantarci, Kejal and Schwarz, Christopher G and Reid, Robert I and Przybelski, Scott A and Lesnick, Timothy G and Zuk, Samantha M and Senjem, Matthew L and Gunter, Jeffrey L and Lowe, Val and Machulda, Mary M and Knopman, David S and Petersen, Ronald C and Jack, Clifford R
JAMA Neurology, ISSN 2168-6149, 12/2014, Volume 71, Issue 12, pp. 1547 - 1554
IMPORTANCE: Pathophysiologic mechanisms leading to loss of white matter integrity and the temporal positioning of biomarkers of white matter integrity relative... 
EPISODIC MEMORY | HUMAN BRAIN | MRI | ALZHEIMERS-DISEASE | HYPOTHETICAL MODEL | REGISTRATION | MILD COGNITIVE IMPAIRMENT | DYNAMIC BIOMARKERS | ASSOCIATION | CLINICAL NEUROLOGY | DECLINE | Neurodegenerative Diseases - pathology | White Matter - metabolism | Cognitive Dysfunction - metabolism | Humans | Male | Positron-Emission Tomography | Cognitive Dysfunction - pathology | Neurodegenerative Diseases - metabolism | Cognitive Dysfunction - physiopathology | White Matter - pathology | Diffusion Tensor Imaging - methods | Neurodegenerative Diseases - physiopathology | Anisotropy | Gray Matter - metabolism | Amyloid beta-Peptides - metabolism | Gray Matter - pathology | Aged, 80 and over | Biomarkers | Female | Aged | Longitudinal Studies
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