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Cancer Research, ISSN 0008-5472, 07/2017, Volume 77, Issue 14, pp. 3894 - 3907
Oncolytic viruses selectively lyse tumor cells, disrupt immunosuppression within the tumor, and reactivate antitumor immunity, but they have yet to live up to... 
OX40 | VIRUS | COLONY-STIMULATING FACTOR | EFFICACY | ONCOLOGY | B7-H1 EXPRESSION | GLIOMA | ANTIBODY | CHECKPOINTS | OX40 Ligand - genetics | Cancer Vaccines - pharmacology | Humans | OX40 Ligand - biosynthesis | Neoplasms - virology | Neoplasms - therapy | Melanoma, Experimental - immunology | Glioma - therapy | HEK293 Cells | Melanoma, Experimental - virology | A549 Cells | Immunomodulation | Melanoma, Experimental - therapy | Mice, Inbred C57BL | Glioma - immunology | Oncolytic Viruses - genetics | Lung Neoplasms - therapy | Lung Neoplasms - virology | B7-H1 Antigen - immunology | Oncolytic Virotherapy - methods | Lung Neoplasms - immunology | Animals | B7-H1 Antigen - antagonists & inhibitors | OX40 Ligand - immunology | Mice, Nude | Neoplasms - immunology | Oncolytic Viruses - immunology | Oncolytic Viruses - physiology | Cell Line, Tumor | Mice | CD8-Positive T-Lymphocytes - immunology | Glioma - virology | Cell proliferation | Therapy | Toxicity | CD8 antigen | Vaccination | Viruses | Activation | Lymphocytes T | Immunity | Modulators | Recruitment | Cell activation | Lymphocytes | Oncolysis | Antigens | Immunological memory | Effectiveness | Tumor cells | Immunodeficiency | Costimulator | Immunosuppression | Ox40L protein | Immune checkpoint | Immunogenicity | Tumor necrosis factor | Cell death | Antigen (tumor-associated) | PD-L1 protein | Ligands | Cancer | Apoptosis | Index Medicus | PD-L1 | oncolytic adenovirus | Delta-24-RGDOX | OX40L | Delta-24-RGD
Journal Article
Blood, ISSN 0006-4971, 11/2019, Volume 134, Issue Supplement_1, pp. 1746 - 1746
Background: In secondary lymphatic organs (SLO), chronic lymphocytic leukemia (CLL) cells form characteristic pseudo-follicles, also called proliferation... 
Journal Article
Cancer Research, ISSN 0008-5472, 10/2017, Volume 77, Issue 19, pp. 5374 - 5383
Early-phase clinical trials evaluating CD8(+) T cell-eliciting, HER2-derived peptide vaccines administered to HER2(+) breast cancer patients in the adjuvant... 
RESPONSES IN-VIVO | IMMUNE-COMPLEXES | FC-GAMMA RECEPTORS | ONCOLOGY | BREAST-CANCER PATIENTS | ANTIGEN PRESENTATION | MONOCLONAL-ANTIBODIES | EXPRESSION | CD8(+) T-CELLS | TUMOR-IMMUNITY | TRANSGENIC MICE | T-Lymphocytes, Cytotoxic - immunology | Cell Proliferation | Trastuzumab - therapeutic use | Breast Neoplasms - immunology | Dendritic Cells - immunology | Humans | Receptor, ErbB-2 - metabolism | Mice, Transgenic | Breast Neoplasms - drug therapy | Breast Neoplasms - metabolism | Cancer Vaccines - therapeutic use | Vaccines, Subunit - therapeutic use | Animals | Female | Mice | Mice, Inbred BALB C | Ovarian Neoplasms - metabolism | Receptor, ErbB-2 - immunology | Tumor Cells, Cultured | CD8-Positive T-Lymphocytes - immunology | Ovarian Neoplasms - drug therapy | Apoptosis | Ovarian Neoplasms - immunology | Flow cytometry | Therapy | Animal models | CD8 antigen | Vaccination | Medical services | Clinical trials | Cytotoxicity | Lymphocytes T | Vaccines | Immunity | Cell activation | Lymphocytes | Immune system | Medical research | Antigen presentation | Immune response | Dendritic cells | Granulocyte-macrophage colony-stimulating factor | Breast cancer | T cell receptors | Adaptive immunity | Patients | ErbB-2 protein | Fc receptors | Cytometry | Monoclonal antibodies | Antitumor activity | Trastuzumab | Cancer | trastuzumab | breast cancer | dendritic cells | cross-presentation | HER2
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, p. e97407
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 174 - 174
Abstract DNA damage and the attendant cellular responses of apoptosis, senescence, and altered differentiation are major drivers of hematopoietic stem cell... 
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 03/2018, Volume 115, Issue 10, pp. E2311 - E2319
Blood cell formation must be appropriately maintained throughout life to provide robust immune function, hemostasis, and oxygen delivery to tissues, and to... 
Inflammation | Ubc13 | Hematopoiesis | STAT3 | PROGENITOR CELLS | STEM-CELLS | UBIQUITIN-CONJUGATING ENZYME | MULTIDISCIPLINARY SCIENCES | EMERGENCY GRANULOPOIESIS | SELF-RENEWAL | INNATE IMMUNE | MYELODYSPLASTIC SYNDROME | HYPER-IGE SYNDROME | hematopoiesis | inflammation | IN-VIVO | NF-KAPPA-B | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 1807 - 1807
Abstract Introduction PD-1 is a negative costimulatory receptor on activated T lymphocytes which counters the activation signal provided by T cell receptor... 
Journal Article
Blood, ISSN 0006-4971, 11/2018, Volume 132, Issue Supplement 1, pp. 4542 - 4542
Abstract Many aggressive hematologic malignancies are exquisitely responsive to immunotherapy. While allogeneic (allo) hematopoietic stem cell transplantation... 
Journal Article
Journal Article
Blood, ISSN 0006-4971, 12/2014, Volume 124, Issue 21, pp. 4110 - 4110
Abstract Proteinase 3 (P3), a serine protease constitutively expressed on the membrane on a fraction of resting granulocytes and commonly existed in primary... 
Journal Article