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Journal Article
Biochemical Journal, ISSN 0264-6021, 07/2011, Volume 438, Issue 1, pp. 177 - 189
Pancreatic β-cell apoptosis induced by palmitate requires high glucose concentrations. Ceramides have been suggested to be important mediators of... 
Journal Article
Cell Death and Differentiation, ISSN 1350-9047, 09/2010, Volume 17, Issue 9, pp. 1474 - 1485
Ischemia/reperfusion injury (IRI) causes inflammation and cell injury as a result of activating innate immune signaling. Toll-like receptor 4 (TLR4) has a key... 
kidney | apoptosis | NAD(P)H oxidase 4 | gp96 | Toll-like receptor 4 | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEATH | ENDOPLASMIC-RETICULUM STRESS | CELL BIOLOGY | ISCHEMIA-REPERFUSION INJURY | REACTIVE OXYGEN | EPITHELIAL-CELLS | NF-KAPPA-B | NADPH OXIDASES | INNATE IMMUNITY | RNA, Small Interfering - genetics | Cell Hypoxia - physiology | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | Apoptosis - drug effects | Epithelial Cells - drug effects | TNF Receptor-Associated Factor 2 - genetics | NADPH Oxidases - metabolism | JNK Mitogen-Activated Protein Kinases - metabolism | Kidney - metabolism | Isoenzymes - metabolism | NADPH Oxidases - genetics | Female | p38 Mitogen-Activated Protein Kinases - metabolism | MAP Kinase Kinase Kinase 5 - metabolism | Kidney Tubules - metabolism | Reperfusion Injury - genetics | Reperfusion Injury - metabolism | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mice, Inbred C57BL | Myeloid Differentiation Factor 88 - genetics | bcl-2-Associated X Protein - metabolism | TNF Receptor-Associated Factor 2 - metabolism | Toll-Like Receptor 4 - genetics | Kidney - cytology | NADPH Oxidase 4 | Toll-Like Receptor 4 - metabolism | Membrane Glycoproteins - genetics | Mice, Knockout | Kidney Tubules - cytology | Animals | Signal Transduction - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Signal Transduction - physiology | Mice | Protein Kinase Inhibitors - pharmacology | Apoptosis - physiology | Myeloid Differentiation Factor 88 - metabolism | Protein Binding - physiology
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 06/2010, Volume 30, Issue 11, pp. 2636 - 2650
Journal Article
Oncogene, ISSN 0950-9232, 11/2017, Volume 36, Issue 47, pp. 6649 - 6657
Journal Article
Oncogene, ISSN 0950-9232, 07/2018, Volume 37, Issue 28, pp. 3852 - 3863
Journal Article
Journal Article
Journal Article
FASEB Journal, ISSN 0892-6638, 05/2018, Volume 32, Issue 5, pp. 2339 - 2353
Journal Article
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, ISSN 1388-1981, 02/2013, Volume 1831, Issue 2, pp. 251 - 262
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, p. e113998
Sphingosine kinase 1 (SK1), one of two SK enzymes, is highly regulated and has been shown to act as a focal point for the action of many growth factors and... 
CHEMOTAXIS | MULTIDISCIPLINARY SCIENCES | ULCERATIVE-COLITIS | SPHINGOSINE-1-PHOSPHATE | EGRESS | TNF-ALPHA | KNOCKOUT MICE | RECEPTORS | CERAMIDE | NEUTROPHIL-LYMPHOCYTE RATIO | CELL-DEATH | Lysophospholipids - metabolism | Phosphotransferases (Alcohol Group Acceptor) - physiology | Mice, Inbred C57BL | Colitis - pathology | Phosphotransferases (Alcohol Group Acceptor) - genetics | Inflammatory Bowel Diseases - metabolism | Mice, Knockout | Phosphotransferases (Alcohol Group Acceptor) - metabolism | Sphingosine - analogs & derivatives | Animals | Hematopoietic System - metabolism | Colitis - chemically induced | Inflammatory Bowel Diseases - pathology | Inflammation - genetics | Mice | Sphingosine - metabolism | Receptors, Lysosphingolipid - metabolism | Enzymes | Inflammation | Colitis | Cytokines | Gastrointestinal diseases | Sphingosine | Inflammatory bowel diseases | Transcription | Syngeneic grafts | Bone marrow transplantation | Inflammatory response | Activation | Kinases | Sphingosine 1-phosphate | Prostaglandin endoperoxide synthase | Receptors | Biological effects | Intestine | Rodents | Bone marrow | Dextran sulfate | Tumor necrosis factor-TNF | Colon | Autocrine signalling | Growth factors | Damage assessment | Sphingosine kinase | Stat3 protein | Transplants | Epithelium | Hemopoiesis | Inflammatory bowel disease | Dextran | Sodium | Neutrophilia | Cyclooxygenase-2
Journal Article