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1. Modelling methodology for physiology and medicine
by Carson, Ewart and Cobelli, Claudio
2014, Second edition., Elsevier insights, ISBN 0124115578
Medicine | Physiology | Mathematical models
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2. Full Text Glucose variability: Timing, risk analysis, and relationship to hypoglycemia in diabetes
by Kovatchev, Boris and Cobelli, Claudio
Diabetes Care, ISSN 0149-5992, 04/2016, Volume 39, Issue 4, pp. 502 - 510
Glucose control, glucose variability (GV), and risk for hypoglycemia are intimately related, and it is now evident that GV is important in both the physiology... 
MATTER | GLYCEMIC VARIABILITY | COUNTERREGULATION | BLOOD-GLUCOSE | ENDOCRINOLOGY & METABOLISM | COMPLICATIONS | INTENSIVE INSULIN THERAPY | INDEXES | Hypoglycemic Agents - therapeutic use | Models, Theoretical | Risk Assessment | Glycated Hemoglobin A - metabolism | Humans | Risk Factors | Biomarkers - blood | Diabetes Mellitus, Type 1 - drug therapy | Diabetes Mellitus, Type 2 - blood | Hyperglycemia - blood | Hypoglycemia - etiology | Diabetes Mellitus, Type 1 - blood | Blood Glucose Self-Monitoring | Hypoglycemia - blood | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Principal Component Analysis | Peptides - therapeutic use | Care and treatment | Usage | Glucose monitors | Blood sugar | Analysis | Diabetes | Hypoglycemia | Risk factors | Glucose | Risk assessment | Optimization | s in Care
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3. Full Text Artificial pancreas: Past, present, future
by Cobelli, Claudio and Renard, Eric and Kovatchev, Boris
Diabetes, ISSN 0012-1797, 11/2011, Volume 60, Issue 11, pp. 2672 - 2682
GLYCEMIC CONTROL | TO-RUN CONTROL | TYPE-1 DIABETIC-PATIENTS | BLOOD-GLUCOSE STABILITY | INTRAPERITONEAL INSULIN | INTERSTITIAL GLUCOSE | ENDOCRINOLOGY & METABOLISM | PLASMA-GLUCOSE | METABOLIC SYSTEMS | LOOP INSULIN DELIVERY | MODEL-PREDICTIVE CONTROL | Blood Chemical Analysis - methods | Blood Glucose - analysis | Pancreas, Artificial - adverse effects | Humans | Pancreas, Artificial - trends | Diabetes Mellitus, Type 1 - metabolism | Insulin Infusion Systems - adverse effects | Insulin - administration & dosage | Insulin Infusion Systems - trends | Diabetes Mellitus, Type 1 - drug therapy | Animals | Computer Simulation | Diabetes Mellitus, Type 1 - blood | Blood Chemical Analysis - trends | Insulin - adverse effects | Insulin - pharmacokinetics | Insulin - therapeutic use | Usage | Care and treatment | Type 1 diabetes | Artificial organs | Diagnosis | Research | Health aspects | Diabetes therapy | s in Diabetes
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4. Modelling methodology for physiology and medicine
by Carson, Ewart R and Cobelli, Claudio
2014, Second edition., Elsevier insights, ISBN 0124115578
Medicine | Models, Theoretical | Physiology
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5. Full Text Modelling methodology for physiology and medicine
by Carson, Ewart R and Cobelli, Claudio
2001, Academic Press series in biomedical engineering, ISBN 0121602451, 437
"Modelling Methodology for Physiology and Medicine" offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modelling... 
Medicine | Physiology | Mathematical models | Mathematics
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6. Full Text Tracer kinetics in biomedical research
: from data to model
by Cobelli, Claudio and Foster, David and Toffolo, Gianna and SpringerLink (Online service)
2000, ISBN 0306464276, 455
1. Introduction. 2. Fundamentals of Tracer Kinetics. 3. The Noncompartmental Model of Multipool Systems. 4. The Compartmental Model. 5. Identifiability of the... 
Pharmacokinetics | Mathematics | Radioactive tracers in biochemistry | Chemistry, Physical organic | Statistics for Life Sciences, Medicine, Health Sciences | Mathematical and Computational Biology | Physical Chemistry | Mathematical Modeling and Industrial Mathematics | Biomedical Engineering and Bioengineering | Statistics | Biomedical engineering
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7. Full Text Yet Another Glucose Variability Index: Time for a Paradigm Change?
by Cobelli, Claudio and Facchinetti, Andrea
Diabetes Technology & Therapeutics, ISSN 1520-9156, 01/2018, Volume 20, Issue 1, pp. 1 - 3
Commentaries | GLYCEMIC CONTROL | ENDOCRINOLOGY & METABOLISM | Blood Glucose - analysis | Humans | Care and treatment | Glycemic index | Research | Diabetes | Glucose monitors | Analysis
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8. Full Text MOtoNMS: A MATLAB toolbox to process motion data for neuromusculoskeletal modeling and simulation
by Mantoan, Alice and Pizzolato, Claudio and Sartori, Massimo and Sawacha, Zimi and Cobelli, Claudio and Reggiani, Monica
Source Code for Biology and Medicine, ISSN 1751-0473, 11/2015, Volume 10, Issue 12, p. 12
Background: Neuromusculoskeletal modeling and simulation enable investigation of the neuromusculoskeletal system and its role in human movement dynamics. These... 
OpenSim | Data processing | Neuromusculoskeletal modeling | C3D | Motion data | Musculoskeletal system | Usage | Computer-generated environments | Computer simulation | Physiological aspects | Human mechanics | Models | Research | Studies | Biomechanics | Researchers | Simulation | Operating systems | Laboratories | User interface | Data collection | Proprietary
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9. Full Text Comparison of markerless and marker-based motion capture technologies through simultaneous data collection during gait: Proof of concept
by Ceseracciu, Elena and Sawacha, Zimi and Cobelli, Claudio
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e87640
During the last decade markerless motion capture techniques have gained an increasing interest in the biomechanics community. In the clinical field, however,... 
MOVEMENT | SHAPE | JOINT COORDINATE SYSTEM | STEREOPHOTOGRAMMETRY | MULTIDISCIPLINARY SCIENCES | HIP | Photography | Motion | Humans | Imaging, Three-Dimensional - methods | Data Collection | Calibration | Gait - physiology | Biomechanics | Comparative analysis | Computer animation | Data entry | Computer programs | Knee | Mean square values | Gait | Data acquisition | Synchronism | Data processing | Digital cameras | Knee (anatomy) | Systems analysis | Synchronization | Hip | Motion perception | Posture | Ankle | Engineering | Planes | Kinematics | Human mechanics | Data collection | Cameras | Motion capture | Protocol
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10. Full Text Accurate measurement of postprandial glucose turnover: Why is it difficult and how can it be done (relatively) simply?
by Rizza, Robert A and Toffolo, Gianna and Cobelli, Claudio
Diabetes, ISSN 0012-1797, 05/2016, Volume 65, Issue 5, pp. 1133 - 1145
Fasting hyperglycemia occurs when an excessive rate of endogenous glucose production (EGP) is not accompanied by an adequate compensatory increase in the rate... 
Deuterium | Reproducibility of Results | Blood Glucose - analysis | Humans | Carbohydrate Metabolism | Carbon Isotopes | Tritium | Dietary Carbohydrates - metabolism | Intestinal Absorption | Algorithms | Animals | Glycogen - metabolism | Models, Biological | Postprandial Period | Glucose - metabolism | Glycolysis | Glycogenolysis | Carbon Radioisotopes | Gluconeogenesis | Plasma | Hyperglycemia | Glucose | Diabetes | Meals | Index Medicus | Abridged Index Medicus | s in Diabetes
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11. Biological systems
: an engineering approach to physiology
by Albergoni, Vincenzo and Cobelli, Claudio and Francini, Giuseppe L
1974, 118
Biology | Physiology | Simulation methods
Book
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12. Full Text Insulin Sensitivity Index-Based Optimization of Insulin to Carbohydrate Ratio: In Silico Study Shows Efficacious Protection Against Hypoglycemic Events Caused by Suboptimal Therapy
by Schiavon, Michele and Dalla Man, Chiara and Cobelli, Claudio
Diabetes Technology & Therapeutics, ISSN 1520-9156, 02/2018, Volume 20, Issue 2, pp. 98 - 105
Background and Aim: The insulin to carbohydrate ratio (CR) is a parameter used by patients with type 1 diabetes (T1D) to calculate the premeal insulin bolus.... 
Original Articles | Continuous glucose monitoring | Type 1 diabetes | Bolus calculator | Insulin bolus | Diabetes therapy | SYSTEM | ARTIFICIAL PANCREAS | GLUCOSE CONTROL | SETTINGS | ADJUSTMENT | TYPE-1 DIABETES IMPLICATIONS | ORAL-TEST | PEDIATRIC-PATIENTS | ADAPTATION | ENDOCRINOLOGY & METABOLISM | Humans | Blood Glucose | Insulin - administration & dosage | Diabetes Mellitus, Type 1 - drug therapy | Hypoglycemia - prevention & control | Hypoglycemic Agents - administration & dosage | Computer Simulation | Diabetes Mellitus, Type 1 - blood | Blood Glucose Self-Monitoring | Insulin Infusion Systems | Hypoglycemia - blood | Hypoglycemia - chemically induced | Hypoglycemic Agents - adverse effects | Insulin - adverse effects | Measurement | Carbohydrates | Hypoglycemic agents | Research | Insulin | Glucose | Diabetes | Original
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13. Full Text One-Day Bayesian Cloning of Type 1 Diabetes Subjects: Toward a Single-Day UVA/Padova Type 1 Diabetes Simulator
by Visentin, Roberto and Dalla Man, Chiara and Cobelli, Claudio
IEEE Transactions on Biomedical Engineering, ISSN 0018-9294, 11/2016, Volume 63, Issue 11, pp. 2416 - 2424
Objective: The UVA/Padova Type 1 Diabetes (T1DM) Simulator has been shown to be representative of a T1DM population observed in a clinical trial, but has not... 
Artificial pancreas | circadian variability | Sociology | compartmental modeling | Data models | Plasmas | Bayes methods | closed-loop control | in silico | Mathematical model | Insulin | Sugar | INSULIN ACTION | ENGINEERING, BIOMEDICAL | AGE | Blood Glucose - analysis | Humans | Middle Aged | Insulin Resistance | Diabetes Mellitus, Type 1 - metabolism | Circadian Rhythm - physiology | Diabetes Mellitus, Type 1 - drug therapy | Computer Simulation | Bayes Theorem | Adult | Blood Glucose - metabolism | Insulin - therapeutic use | Pancreas, Artificial | Usage | Plasma physics | Mathematical models | Biochemistry | Research | Glucose | Parameters | Absorption | Computer simulation | Simulation | Bayesian analysis
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14. Full Text International Consensus on Use of Continuous Glucose Monitoring
by Danne, Thomas and Nimri, Revital and Battelino, Tadej and Bergenstal, Richard M and Close, Kelly L and DeVries, J. Hans and Garg, Satish and Heinemann, Lutz and Hirsch, Irl and Amiel, Stephanie A and Beck, Roy and Bosi, Emanuele and Buckingham, Bruce and Cobelli, Claudio and Dassau, Eyal and Doyle, Francis J and Heller, Simon and Hovorka, Roman and Jia, Weiping and Jones, Tim and Kordonouri, Olga and Kovatchev, Boris and Kowalski, Aaron and Laffel, Lori and Maahs, David and Murphy, Helen R and Nørgaard, Kirsten and Parkin, Christopher G and Renard, Eric and Saboo, Banshi and Scharf, Mauro and Tamborlane, William V and Weinzimer, Stuart A and Phillip, Moshe
Diabetes care, ISSN 0149-5992, 2017, Volume 40, Issue 12, pp. 1631 - 1640
Measurement of glycated hemoglobin (HbA(1c)) has been the traditional method for assessing glycemic control. However, it does not reflect intra- and interday... 
DEPENDENT DIABETES-MELLITUS | EXCHANGE CLINIC REGISTRY | COST-EFFECTIVENESS | GLYCEMIC VARIABILITY | SEVERE HYPOGLYCEMIA | INSULIN PUMP THERAPY | BLOOD-GLUCOSE | ENDOCRINOLOGY & METABOLISM | COUNTERREGULATORY RESPONSES | RANDOMIZED CONTROLLED-TRIAL | HEMOGLOBIN A(1C) LEVELS | Hypoglycemic Agents - therapeutic use | Blood Glucose Self-Monitoring - standards | Physicians | Glycated Hemoglobin A - metabolism | Humans | Clinical Trials as Topic | Hypoglycemia - drug therapy | Hyperglycemia - drug therapy | Consensus | Diabetes Mellitus, Type 1 - drug therapy | Diabetes Mellitus, Type 2 - blood | Reference Standards | Hyperglycemia - blood | International Agencies | Research Personnel | Diabetes Mellitus, Type 1 - blood | Hypoglycemia - blood | Blood Glucose - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Insulin - therapeutic use | Usage | Control | Care and treatment | Diabetes | Glucose monitors | Blood sugar | Medical personnel | Hyperglycemia | Complications | Diabetes mellitus | Hemoglobin | Data processing | Microvasculature | Glucose | Hypoglycemia | Monitoring | Life Sciences | Continuous Glucose Monitoring and Risk of Hypoglycemia | 0301
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15. Introduction to modeling in physiology and medicine
by Cobelli, Claudio and Carson, Ewart R
2008, 1st ed., Academic Press series in biomedical engineering, ISBN 0121602400
Medicine | Physiology | Mathematical models
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16. Introduction to modeling in physiology and medicine
by Cobelli, Claudio and Carson, Ewart R
2008, 1st ed., Academic Press series in biomedical engineering, ISBN 0121602400
This unified modeling textbook for students of biomedical engineering provides a complete course text on the foundations, theory and practice of modeling and... 
Medicine | Models, Biological | Physiology | Physiological Processes | Mathematical models
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17. Introduction to modeling in physiology and medicine
by Cobelli, Claudio and Carson, Ewart R and ebrary, Inc
2008, 1st ed., Academic Press series in biomedical engineering, ISBN 0121602400
Medicine | Physiology | Mathematical models
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18. Full Text Exocrine and endocrine interactions in cystic fibrosis: A potential key to understanding insulin secretion in health and disease?
by Cobelli, Claudio and Vella, Adrian
Diabetes, ISSN 0012-1797, 01/2017, Volume 66, Issue 1, pp. 20 - 22
  The study of ...-cell function in vivo has been hampered by the relative inaccessibility of the pancreas as well as the hybrid exocrine/endocrine nature of... 
GLP-1 | GLUCAGON-LIKE PEPTIDE-1 | Y GASTRIC BYPASS | MASS | ENDOCRINOLOGY & METABOLISM | HUMANS | ARGININE | ORAL GLUCOSE | MODEL | GLUCOSE-TOLERANCE | BETA-CELL FUNCTION | Exocrine glands | Cystic fibrosis | Pancreatic beta cells | Care and treatment | Research | Nutrients | Diabetes | Pancreas | Insulin | Index Medicus | Abridged Index Medicus | Commentaries
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19. Full Text Type-1 Diabetes Patient Decision Simulator for In Silico Testing Safety and Effectiveness of Insulin Treatments
by Vettoretti, Martina and Facchinetti, Andrea and Sparacino, Giovanni and Cobelli, Claudio
IEEE Transactions on Biomedical Engineering, ISSN 0018-9294, 06/2018, Volume 65, Issue 6, pp. 1281 - 1290
Objective: Type-1 diabetes (T1D) treatment requires exogenous insulin administrations finely tuned based on glucose monitoring to avoid hyper/hypoglycemia. The... 
Continuous glucose monitoring | type 1 diabetes | modeling | simulation | Biomedical measurement | Clinical trials | Diabetes | Insulin | Sugar | Monitoring | self-monitoring of blood glucose | Simulation | Type 1 diabetes | Modeling | Self-monitoring of blood glucose | VARIABILITY | TRIAL | ENGINEERING, BIOMEDICAL | GLUCOSE | HYPOGLYCEMIA | ADULTS | MODEL | Medical research | Computer simulation | Glucagon | Diabetes mellitus | Glucose | Hypoglycemia | Patients | Hyperglycemia | Data buses | Reliability analysis | Kinetics | Safety
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20. Full Text The UVA/PADOVA Type 1 Diabetes Simulator
: New Features
by Man, Chiara Dalla and Micheletto, Francesco and Lv, Dayu and Breton, Marc and Kovatchev, Boris and Cobelli, Claudio
Journal of Diabetes Science and Technology, ISSN 1932-2968, 1/2014, Volume 8, Issue 1, pp. 26 - 34
Objective: Recent studies have provided new insights into nonlinearities of insulin action in the hypoglycemic range and into glucagon kinetics as it relates... 
Computer simulation | Modeling | Diabetes control | computer simulation | modeling | Original | diabetes control
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