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association (2) 2
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cells, cultured (2) 2
chikungunya (2) 2
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diffuse alveolar hemorrhage (2) 2
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enthesopathy (2) 2
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follow-up studies (2) 2
idiopathic inflammatory myopathies (2) 2
immunology (2) 2
immunosuppressive agents - therapeutic use (2) 2
interleukin-15 - biosynthesis (2) 2
interstitial lung-disease (2) 2
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lung diseases (2) 2
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rituximab (2) 2
single-center (2) 2
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1. Full Text Diagnostic accuracy of enthesis ultrasound in the diagnosis of early spondyloarthritis
by de Miguel, Eugenio and Muñoz-Fernández, Santiago and Castillo, Concepción and Cobo-Ibáñez, Tatiana and Martín-Mola, Emilio
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2011, Volume 70, Issue 3, pp. 434 - 439
Objective To determine the sensitivity and specificity of enthesis ultrasound for the diagnostic classification of early spondyloarthritis. Methods A... 
SPONDYLARTHRITIS | MULTICENTER | DOUBLE-BLIND | RHEUMATOLOGY | PSORIATIC-ARTHRITIS | SPINAL INFLAMMATION | ULTRASONOGRAPHY | INFLIXIMAB | CLASSIFICATION CRITERIA | ACTIVE ANKYLOSING-SPONDYLITIS | POWER DOPPLER | Diagnosis, Differential | Patellar Ligament - diagnostic imaging | Spondylarthritis - diagnostic imaging | Humans | Middle Aged | Male | Achilles Tendon - diagnostic imaging | Ultrasonography, Doppler - methods | Epidemiologic Methods | Tendons - diagnostic imaging | Adult | Female | Early Diagnosis | Usage | Diagnosis, Ultrasonic | Analysis | Spondyloarthropathies | Physiological aspects | Diagnosis | Research | Tendons
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2. Full Text Serious infections in patients with rheumatoid arthritis and other immune-mediated connective tissue diseases exposed to anti-TNF or rituximab: data from the Spanish registry BIOBADASER 2.0
by Cobo-Ibáñez, Tatiana and Descalzo, Miguel Ángel and Loza-Santamaría, Estibaliz and Carmona, Loreto and Muñoz-Fernández, Santiago
Rheumatology International, ISSN 0172-8172, 7/2014, Volume 34, Issue 7, pp. 953 - 961
Data on infections in patients exposed to biologic therapies are mainly focused on rheumatoid arthritis (RA). Little is known about the safety profile in other... 
Serious infections | Medicine & Public Health | Immune-mediated connective tissue diseases | Rheumatoid arthritis | Rheumatology | Anti-TNF | Rituximab | MORTALITY | RATES | RISK-FACTORS | THERAPY | SAFETY | RHEUMATOLOGY | Virus Diseases - epidemiology | Connective Tissue Diseases - epidemiology | Antirheumatic Agents - administration & dosage | Humans | Middle Aged | Antibodies, Monoclonal, Murine-Derived - administration & dosage | Male | Virus Diseases - complications | Arthritis, Rheumatoid - complications | Incidence | Bacterial Infections - complications | Arthritis, Rheumatoid - drug therapy | Registries - statistics & numerical data | Antirheumatic Agents - adverse effects | Adult | Female | Opportunistic Infections - complications | Opportunistic Infections - epidemiology | Comorbidity | Risk Factors | Arthritis, Rheumatoid - epidemiology | Connective Tissue Diseases - drug therapy | Bacterial Infections - epidemiology | Aged | Antibodies, Monoclonal, Murine-Derived - adverse effects | Connective Tissue Diseases - complications | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Antimitotic agents | Rheumatoid factor | Care and treatment | Tumor necrosis factor | Analysis | Mortality | Resveratrol | Arthritis | Antineoplastic agents | Health aspects
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3. Full Text IL-15 expression on RA synovial fibroblasts promotes B cell survival
by Benito-Miguel, Marta and García-Carmona, Yolanda and Balsa, Alejandro and Bautista-Caro, María-Belén and Arroyo-Villa, Irene and Cobo-Ibáñez, Tatiana and Bonilla-Hernán, María Gema and de Ayala, Carlos Pérez and Sánchez-Mateos, Paloma and Martín-Mola, Emilio and Miranda-Carús, María-Eugenia
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40620
Introduction: The purpose of this study was to examine the role of RA Synovial Fibroblast (RASFib) IL-15 expression on B cell survival. Methods: Magnetically... 
BETA-CHAIN | NECROSIS-FACTOR | MULTIDISCIPLINARY SCIENCES | DISEASE | FOLLICULAR DENDRITIC CELLS | SYNOVIOCYTES | RECEPTOR | PROLIFERATION | T-CELL | DIFFERENTIATION | RHEUMATOID-ARTHRITIS PATIENTS | Cell Survival - drug effects | Coculture Techniques | Humans | Middle Aged | Synovial Membrane - immunology | Male | Receptors, Interleukin-15 - metabolism | Synovial Membrane - metabolism | Arthritis, Rheumatoid - metabolism | B-Lymphocytes - drug effects | Interleukin-15 - pharmacology | B-Cell Activating Factor - metabolism | B-Lymphocytes - immunology | Interleukin-15 - metabolism | Aged, 80 and over | Female | Immunologic Memory | Aged | Arthritis, Rheumatoid - immunology | Vascular Cell Adhesion Molecule-1 - metabolism | B-Lymphocytes - metabolism | Fibroblasts - metabolism | B cells | Lymphocyte receptors | Cell culture | Memory cells | Vascular cell adhesion molecule 1 | Immunological memory | Cell survival | Chains | T cell receptors | Joint surgery | Interleukin 15 | Survival | Blood | Lymphocytes B | Lymphocytes | BLyS protein | Neutralizing | Peripheral blood | Fibroblasts | Interleukin 15 receptors | Apoptosis
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4. Full Text Multidisciplinary dermatology–rheumatology management for patients with moderate-to-severe psoriasis and psoriatic arthritis: a systematic review
by Cobo-Ibáñez, Tatiana and Cobo-Ibáñez, Tatiana and Villaverde, Virginia and Villaverde, Virginia and Seoane-Mato, Daniel and Seoane-Mato, Daniel and Muñoz-Fernández, Santiago and Muñoz-Fernández, Santiago and Guerra, Mercedes and Guerra, Mercedes and del Campo, Petra Díaz and del Campo, Petra Díaz and Cañete, Juan D and Cañete, Juan D
Rheumatology International, ISSN 0172-8172, 2/2016, Volume 36, Issue 2, pp. 221 - 229
The aim of the study was to analyze the efficacy and satisfaction of multidisciplinary dermatology–rheumatology management for patients with moderate-to-severe... 
Medicine & Public Health | Psoriasis | Rheumatology | Systematic review | Management | Consultations | Multidisciplinary | Psoriatic arthritis | SYMPTOMS | PREVALENCE | RHEUMATOLOGY | MODULAR APPROACH | DISEASE | UVEITIS | EXPERIENCE | SCREENING QUESTIONNAIRE | EPIDEMIOLOGY | Severity of Illness Index | Dermatology | Humans | Psoriasis - diagnosis | Patient Care Team | Arthritis, Psoriatic - diagnosis | Treatment Outcome | Remission Induction | Patient Satisfaction | Interdisciplinary Communication | Time Factors | Waiting Lists | Referral and Consultation | Arthritis, Psoriatic - therapy | Psoriasis - therapy | Care and treatment | Analysis
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5. Full Text Overlap myositis, a distinct entity beyond primary inflammatory myositis: A retrospective analysis of a large cohort from the REMICAM registry
by Nuño‐Nuño, Laura and Joven, Beatriz Esther and Carreira, Patricia E and Maldonado‐Romero, Valentina and Larena‐Grijalba, Carmen and Llorente Cubas, Irene and Tomero, Eva and Barbadillo‐Mateos, María Carmen and García de la Peña Lefebvre, Paloma and Ruiz‐Gutiérrez, Lucía and López‐Robledillo, Juan Carlos and Moruno‐Cruz, Henry and Pérez, Ana and Cobo‐Ibáñez, Tatiana and Almodóvar, Raquel and Lojo, Leticia and García de Yébenes, María Jesús and López‐Longo, Francisco Javier
International Journal of Rheumatic Diseases, ISSN 1756-1841, 08/2019, Volume 22, Issue 8, pp. 1393 - 1401
Background Inflammatory idiopathic myositis (IIM) comprises a heterogeneous group of systemic muscular diseases that can occur together with other connective... 
mortality | overlap myositis | polymyositis | dermatomyositis | inflammatory idiopathic myositis | SURVIVAL | PROGNOSTIC-FACTORS | LABORATORY FEATURES | CONNECTIVE-TISSUE DISEASE | CLINICAL-FEATURES | TERM | RHEUMATOLOGY | SYSTEMIC-SCLEROSIS | INTERSTITIAL LUNG-DISEASE | Rheumatoid factor | Systemic lupus erythematosus | Systemic scleroderma | Analysis | Mortality | Scleroderma (Disease) | Myositis | Respiratory tract diseases | Arthritis | Health aspects | Thrombocytopenia | Sjogren's syndrome | Muscular diseases | Connective tissue diseases | Lung diseases | Dermatomyositis | Infections | Inflammation | Survival | Patients | Polymyositis | Rheumatoid arthritis | Systemic sclerosis | Medical prognosis | Dysphagia | Mixed connective tissue disease
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6. Full Text Long-term pulmonary outcomes and mortality in idiopathic inflammatory myopathies associated with interstitial lung disease
by Cobo-Ibáñez, Tatiana and López-Longo, Francisco-Javier and Joven, Beatriz and Carreira, Patricia E and Muñoz-Fernández, Santiago and Maldonado-Romero, Valentina and Larena-Grijalba, Carmen and Cubas, Irene Llorente and Muriel, Eva Tomero and Mateos, Carmen Barbadillo and de la Peña Lefebvre, Paloma García and Gomez-Gomez, Alejandro and Nogal, Laura Barrio and Pérez, Ana and Almodovar, Raquel and Lojo, Leticia and Ruiz-Gutiérrez, Lucía and López-Robledillo, Juan Carlos and García de Yébenes, María Jesús and Nuño-Nuño, Laura
Clinical Rheumatology, ISSN 0770-3198, 03/2019, Volume 38, Issue 3, pp. 803 - 815
ObjectiveTo study prognostic factors in different types of idiopathic inflammatory myopathies (IIM) associated with interstitial lung disease (ILD).Patients... 
Myositis | Prognosis | Oxygen therapy | Interstitial lung disease | Survival | Respiratory function tests | DERMATOMYOSITIS | PROGNOSTIC-FACTORS | POLYMYOSITIS | SINGLE-CENTER | CONNECTIVE-TISSUE DISEASE | RHEUMATOLOGY | CLINICAL-MANIFESTATIONS | REVISED CRITERIA | COHORT | RETROSPECTIVE ANALYSIS | Medical research | Mortality | Analysis | Lung diseases | Medicine, Experimental | Pulmonary function tests | Health aspects | Respiratory function | Polymyositis | Medical prognosis | Dermatomyositis | Inflammation | Regression analysis | Diagnosis | Multivariate analysis | Erythema
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7. Full Text Efficacy and safety of rituximab in the treatment of non-renal systemic lupus erythematosus: A systematic review
by Cobo-Ibáñez, Tatiana, MD, PhD and Loza-Santamaría, Estíbaliz, MD and Pego-Reigosa, José María, MD, PhD and Marqués, Alejandro Olivé, MD, PhD and Rúa-Figueroa, Íñigo, MD and Fernández-Nebro, Antonio, MD, PhD and Cáliz, Rafael Cáliz, MD and López Longo, Francisco Javier, MD, PhD and Muñoz-Fernández, Santiago, MD, PhD
Seminars in Arthritis and Rheumatism, ISSN 0049-0172, 2014, Volume 44, Issue 2, pp. 175 - 185
Abstract Objective To analyse the efficacy and safety of rituximab in the treatment of non-renal systemic lupus erythematosus (SLE). Methods We systematically... 
Rheumatology | Rituximab | Systematic review | Systemic lupus erythematosus | CYCLOPHOSPHAMIDE | B-CELL DEPLETION | RHEUMATOLOGY | SLE | TERM EFFICACY | PHASE II/III | THERAPY | PREDICTORS | ANTI-CD20 | LONGITUDINAL ANALYSIS | REMISSION | Outcome Assessment (Health Care) | Humans | Lupus Erythematosus, Systemic - drug therapy | Antirheumatic Agents - adverse effects | Treatment Outcome | Antibodies, Monoclonal, Murine-Derived - adverse effects | Antibodies, Monoclonal, Murine-Derived - therapeutic use | Antirheumatic Agents - therapeutic use | Lupus | Care and treatment | Analysis
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8. Full Text Mortality and prognostic factors in idiopathic inflammatory myositis: a retrospective analysis of a large multicenter cohort of Spain
by Nuño-Nuño, Laura and Joven, Beatriz Esther and Carreira, Patricia E and Maldonado-Romero, Valentina and Larena-Grijalba, Carmen and Cubas, Irene Llorente and Tomero, Eva Gloria and Barbadillo-Mateos, María Carmen and De la Peña Lefebvre, Paloma García and Ruiz-Gutiérrez, Lucía and López-Robledillo, Juan Carlos and Moruno-Cruz, Henry and Pérez, Ana and Cobo-Ibáñez, Tatiana and Almodóvar González, Raquel and Lojo, Leticia and García De Yébenes, María Jesús and López-Longo, Francisco Javier
Rheumatology International, ISSN 0172-8172, 11/2017, Volume 37, Issue 11, pp. 1853 - 1861
The present study was undertaken to assess mortality, causes of death, and associated prognostic factors in a large cohort of patients diagnosed with... 
Idiopathic inflammatory myositis | Prognosis | Medicine & Public Health | Overlap myositis | Survival | Rheumatology | CRITERIA | DERMATOMYOSITIS | LONG-TERM SURVIVAL | POLYMYOSITIS | CLASSIFICATION | LABORATORY FEATURES | RHEUMATOLOGY | SYSTEMIC-SCLEROSIS | INTERSTITIAL LUNG-DISEASE | MYOPATHIES | PREDICTIVE FACTORS | Humans | Middle Aged | Myositis - mortality | Adult | Female | Male | Aged | Retrospective Studies | Cause of Death | Myositis | Respiratory tract diseases | Health aspects | Analysis | Mortality | Medical prognosis
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9. Full Text The effect of smoking on clinical and structural damage in patients with axial spondyloarthritis: a systematic literature review
by Villaverde-García, Virginia and Cobo-Ibáñez, Tatiana and Candelas-Rodríguez, Gloria and Seoane-Mato, Daniel and Campo-Fontecha, Petra Díaz del and Guerra, Mercedes and Muñoz-Fernández, Santiago and Cañete, Juan D
Seminars in Arthritis and Rheumatism, ISSN 0049-0172, 2016, Volume 46, Issue 5, pp. 569 - 583
Abstract Objectives To evaluate the association between smoking and clinical parameters and structural damage in axial spondyloarthritis (axSpA). Methods We... 
Rheumatology | BASDAI | Disease activity | ASQoL | mSASSS | Systematic review | radiographic progression | Euro-QoL | BASRI | HAQ-S | Spondyloarthritis | BASMI | Tobacco | BASFI | quality of life | Ankylosing spondylitis | ASDAS | Smoking | RHEUMATOID-ARTHRITIS | FUNCTIONAL ABILITY | LUPUS-ERYTHEMATOSUS | SPINAL MOBILITY | ANKYLOSING-SPONDYLITIS PATIENTS | BASEL | QUALITY-OF-LIFE | RISK-FACTORS | RHEUMATOLOGY | SOCIETY CLASSIFICATION CRITERIA | DISEASE-ACTIVITY | CIGARETTE-SMOKING | Severity of Illness Index | Prospective Studies | Cross-Sectional Studies | Smoking - epidemiology | Humans | Female | Male | Spondylitis, Ankylosing - physiopathology | Spondylitis, Ankylosing - pathology | Case-Control Studies | Disease Progression | Medicine, Experimental | Medical research | Care and treatment
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10. Full Text Efficacy and safety of biological therapy compared to synthetic immunomodulatory drugs or placebo in the treatment of Behçet’s disease associated uveitis: a systematic review
by Urruticoechea-Arana, Ana and Urruticoechea-Arana, Ana and Cobo-Ibáñez, Tatiana and Cobo-Ibáñez, Tatiana and Villaverde-García, Virginia and Villaverde-García, Virginia and Santos Gómez, Montserrat and Santos Gómez, Montserrat and Loza, Estíbaliz and Loza, Estíbaliz and Vargas-Osorio, Kelly and Vargas-Osorio, Kelly and Fariñas Padrón, Leslie and Fariñas Padrón, Leslie and Diaz-Gonzalez, Federico and Diaz-Gonzalez, Federico and Calvo-Río, Vanesa and Calvo-Río, Vanesa and Blanco, Ricardo and Blanco, Ricardo
Rheumatology International, ISSN 0172-8172, 1/2019, Volume 39, Issue 1, pp. 47 - 58
The aim of this study is to compare the efficacy and safety of biological therapy with cyclosporin A (CsA), azathioprine (AZA), or placebo in uveitis flares... 
Medicine & Public Health | Behçet’s disease | Rheumatology | Uveitis | Systematic literature review | Biologic therapy
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11. Full Text Efficacy and safety of biological therapy compared to synthetic immunomodulatory drugs or placebo in the treatment of Behcet's disease associated uveitis: a systematic review
by Urruticoechea-Arana, A and Cobo-Ibanez, T and Villaverde-Garcia, V and Gomez, MS and Loza, E and Vargas-Osorio, K and Padron, LF and Diaz-Gonzalez, F and Calvo-Rio, V and Blanco, R
RHEUMATOLOGY INTERNATIONAL, ISSN 0172-8172, 01/2019, Volume 39, Issue 1, pp. 47 - 58
The aim of this study is to compare the efficacy and safety of biological therapy with cyclosporin A (CsA), azathioprine (AZA), or placebo in uveitis flares... 
REFRACTORY UVEITIS | MULTICENTER | ADALIMUMAB | AZATHIOPRINE | Behcet's disease | RHEUMATOLOGY | OCULAR COMPLICATIONS | INTERFERON ALPHA-2A | Uveitis | INFLIXIMAB | CORTICOSTEROIDS | Systematic literature review | Biologic therapy | CYCLOSPORINE
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12. Full Text Lipoprotein(a) concentrations in rheumatoid arthritis on biologic therapy: Results from the CARdiovascular in rheuMAtology study project
by García-Gómez, Carmen, MD, PhD and Martín-Martínez, Maria A., MD and Castañeda, Santos, MD, PhD and Sanchez-Alonso, Fernando, MD and Uriarte-Ecenarro, Miren, MD and González-Juanatey, Carlos, MD, PhD and Romera-Baures, Montserrat, MD, PhD and Santos-Rey, José, MD and Pinto-Tasende, José Antonio, MD, PhD and Quesada-Masachs, Estefanía, MD and Tornero-Molina, Jesús, MD, PhD and Martínez-González, Olga, MD, PhD and Cobo-Ibáñez, Tatiana, MD, PhD and Chamizo-Carmona, Eugenio, MD and Manrique-Arija, Sara, MD, PhD and Fábregas-Canales, Dolores, MD and Díaz-González, Federico, MD, PhD and Llorca, Javier, MD, PhD and González-Gay, Miguel A., MD, PhD and CARMA Project Collaborative Grp and CARMA Project Collaborative Group
Journal of Clinical Lipidology, ISSN 1933-2874, 2017, Volume 11, Issue 3, pp. 749 - 756.e3
Background Plasma concentrations of lipoprotein (a) (Lp(a)), a lipoprotein with atherogenic and thrombogenic properties, have a strong genetic basis, although... 
Cardiovascular | Cardiovascular disease | Lipoprotein(a) | Tocilizumab | Rheumatoid arthritis | Biologics | VASCULAR-DISEASE | IMPACT | LIPID PROFILE | INFLAMMATION | PREDICTORS | SERUM-LEVELS | PHARMACOLOGY & PHARMACY | GENETIC RISK-FACTOR | ASSOCIATION | Arthritis, Rheumatoid - therapy | Biological Therapy | Cross-Sectional Studies | Arthritis, Rheumatoid - blood | Humans | Middle Aged | Adult | Female | Male | Risk | Lipoprotein(a) - blood | Proteolipids | Care and treatment | Lipoproteins | Physiological aspects | Research | Blood lipoproteins
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13. Full Text A Dual Action of Rheumatoid Arthritis Synovial Fibroblast IL-15 Expression on the Equilibrium between CD4+CD25+ Regulatory T Cells and CD4+CD25- Responder T Cells
by Benito-Miguel, Marta and Garcia-Carmona, Yolanda and Balsa, Alejandro and Perez de Ayala, Carlos and Cobo-Ibanez, Tatiana and Martin-Mola, Emilio and Miranda-Carus, Maria-Eugenia
The Journal of Immunology, ISSN 0022-1767, 12/2009, Volume 183, Issue 12, pp. 8268 - 8279
We previously described that fibroblast-like cells from the synovium of rheumatoid arthritis patients (RASFib) constitutively express intracellular and surface... 
TOLL-LIKE | IN-VITRO | ACTIVATION | DENDRITIC CELLS | MEDIATED SUPPRESSION | REG-CELLS | RECEPTOR | PERIPHERAL-BLOOD | GROWTH-FACTOR | IMMUNOLOGY | FOXP3 | Interleukin-15 - physiology | T-Lymphocytes, Regulatory - metabolism | Coculture Techniques | Humans | Middle Aged | Synovial Membrane - immunology | Synovial Membrane - pathology | Male | CD4-Positive T-Lymphocytes - pathology | Interleukin-15 - biosynthesis | T-Lymphocytes, Regulatory - pathology | T-Lymphocytes, Regulatory - immunology | CD4-Positive T-Lymphocytes - immunology | Young Adult | Arthritis, Rheumatoid - metabolism | Lymphocyte Activation - immunology | Inflammation Mediators - metabolism | Aged, 80 and over | Adult | Female | Osteoarthritis - pathology | Inflammation Mediators - physiology | Fibroblasts - metabolism | Gene Expression Regulation - immunology | Osteoarthritis - immunology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Osteoarthritis - metabolism | Fibroblasts - pathology | Synovial Membrane - metabolism | Arthritis, Rheumatoid - pathology | Interleukin-15 - genetics | Up-Regulation - immunology | Down-Regulation - immunology | Fibroblasts - immunology | Aged | Arthritis, Rheumatoid - immunology
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14. Full Text Hydroxychloroquine is associated with a lower risk of polyautoimmunity: data from the RELESSER Registry
by Mena-Vázquez, Natalia and Fernández-Nebro, Antonio and Pego-Reigosa, José María and Galindo, María and Melissa-Anzola, Ana and Uriarte-Isacelay, Esther and Olivé-Marqués, Alejandro and Aurrecoechea, Elena and Freire, Mercedes and Tomero, Eva and García-Villanueva, María Jesús and Stoye, Claudia and Salas-Heredia, Esteban and Bernal-Vidal, Jose Antonio and Salgado, Eva and Blanco, Ricardo and