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BMC CANCER, ISSN 1471-2407, 11/2019, Volume 19, Issue 1, pp. 1 - 16
Background DNA-crosslinking agents like cisplatin and mitomycin C (MMC) are indispensible for the treatment of many solid malignancies. These anticancer drugs... 
TARGET | CELLS | Fanconi anemia | CUL4 | CANCER | Cisplatin | DAMAGE | Chemotherapy | ONCOLOGY | FANCD2 | S-PHASE | INTERSTRAND CROSS-LINKS | NEDD8-ACTIVATING ENZYME | Crosslink | MOLECULAR-BASIS | ssDNA | ATR | Ubiquitin | Nucleases | DNA replication | Care and treatment | Mitomycin | RNA | Research | Fanconi's anemia | Crosslinked polymers | Ligases | Cell death | Analysis | DNA | Cancer | Crosslink - CUL4 - Fanconi anemia
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2017, Volume 36, Issue 22, pp. 3372 - 3386
Ultraviolet (UV) light induces mutagenic cyclobutane pyrimidine dimers (CPDs) in nucleosomal DNA that is tightly wrapped around histone octamers. How... 
chromatin remodeling | skin cancer | UV light | DNA damage | nucleosomes | DAMAGED DNA | COMPLEX | TRANSCRIPTION ELONGATION-FACTORS | UBIQUITIN LIGASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-BINDING PROTEIN | CELL BIOLOGY | CIS-SYN | CYCLOBUTANE PYRIMIDINE DIMERS | STRUCTURAL BASIS | DUAL INCISION | 6-4 PHOTOPRODUCTS | Pyrimidine Dimers - metabolism | Chromatin - metabolism | Cell Death - radiation effects | Xeroderma Pigmentosum - metabolism | Humans | DNA Repair - radiation effects | Nucleosomes - metabolism | DNA-Binding Proteins - metabolism | DNA Helicases - metabolism | Ultraviolet Rays | Chromatin Assembly and Disassembly - radiation effects | HEK293 Cells | Nucleosomes - radiation effects | Transcription Factor TFIIH - metabolism | DNA Damage | HeLa Cells | Genome, Human | RNA, Small Interfering - metabolism | Chromatin | Immunoprecipitation | DNA polymerase | Toxicity | Downstream effects | Xeroderma pigmentosum | Cytotoxicity | Genomes | Compounds | Recruitment | DNA helicase | XPC protein | Sensors | Lesions | Localization | Repair | Relocation | Deoxyribonucleic acid--DNA | Fractionation | U.V. radiation | Nucleotide excision repair | Damage localization | Ultraviolet radiation | Depletion | Irradiation | Nucleosomes | Dimers | Cyclobutane | Immunofluorescence | Cyclobutane pyrimidine dimers | Chromatin, Epigenetics, Genomics & Functional Genomics | DNA Replication, Repair & Recombination
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 04/2019, Volume 129, Issue 4, pp. 1596 - 1611
Journal Article
The EMBO Journal, ISSN 0261-4189, 11/2017, Volume 36, Issue 22, pp. 3372 - 3386
Journal Article
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