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Cytokine, ISSN 1043-4666, 11/2015, Volume 76, Issue 1, pp. 112 - 112
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2013, Volume 9, Issue 9
  The LRSAM1 protein contains a leucine-rich repeat (LRR) domain, a common feature of PRRs that is often instrumental in the direct binding of microbe-derived... 
Proteins | Salmonella | Membranes | Discrimination | Bacterial infections | Bacteria | Ligands | Autophagy | Immune system
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2014, Volume 111, Issue 16, pp. 6046 - 6051
IFN receptor signaling induces cell-autonomous immunity to infections with intracellular bacterial pathogens. Here, we demonstrate that IFN-inducible guanylate... 
Pathogens | Cell death | Bacteria | Infections | Legionella | Macrophages | Immunity | Cytosol | Vacuoles | Gram negative bacteria | Interferon | Nos2 | Immunity-related GTPases | LEGIONELLA-PNEUMOPHILA INFECTION | IMMUNITY | FLAGELLIN | cell death | RECOGNITION | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | MECHANISMS | interferon | NONCANONICAL INFLAMMASOME ACTIVATION | immunity-related GTPases | VACUOLE | HOST-DEFENSE | TOXOPLASMA-GONDII | Membrane Glycoproteins - metabolism | Apoptosis - drug effects | NADPH Oxidases - metabolism | Cytoplasm - metabolism | Legionella pneumophila - growth & development | Caspases - metabolism | Legionnaires' Disease - microbiology | Salmonella typhimurium - drug effects | Macrophages - microbiology | Salmonella typhimurium - physiology | Mice, Inbred C57BL | Legionella pneumophila - drug effects | Enzyme Activation - drug effects | Mutation - genetics | NADPH Oxidase 2 | Macrophages - metabolism | Animals | Legionnaires' Disease - pathology | Lipopolysaccharides - pharmacology | Legionella pneumophila - physiology | Macrophages - drug effects | Mice | Macrophage Activation - drug effects | Cytoplasm - drug effects | Interferon-gamma - pharmacology | GTP-Binding Proteins - metabolism | Nitric Oxide Synthase Type II - metabolism | Physiological aspects | Protein research | Research | Binding proteins | Apoptosis | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2015, Volume 112, Issue 41, pp. E5628 - E5637
Journal Article
Cytokine, ISSN 1043-4666, 11/2015, Volume 76, Issue 1, p. 112
Many microbes create and maintain pathogen-containing vacuoles (PVs) as an intracellular niche permissive for microbial growth and survival. The destruction of... 
Ubiquitin
Journal Article
Communicative & Integrative Biology, ISSN 1942-0889, 11/2015, Volume 8, Issue 6, pp. 1 - 3
Many intracellular bacterial and protozoan pathogens reside within host cell vacuoles customized by the microbial invaders to fit their needs. Within such... 
Toxoplasma | autophagy | Chlamydia | vacuolar lysis | interferon | guanylate binding proteins | pathogen-containing vacuoles | ubiquitin | immunity related GTPases | Ubiquitin | Guanylate binding proteins | Immunity related GTPases | Interferon | Autophagy | Pathogen-containing vacuoles | Vacuolar lysis | Pathogens | Protozoa
Journal Article
Infection and Immunity, ISSN 0019-9567, 12/2015, Volume 83, Issue 12, pp. 4740 - 4749
Interferon (IFN)-inducible guanylate binding proteins (GBPs) mediate cell-autonomous host resistance to bacterial pathogens and promote inflammasome... 
IFN | AIM2 INFLAMMASOME | IMMUNITY | INFECTIOUS DISEASES | CASPASE-1 | SUSCEPTIBILITY | TRACHOMATIS | INNATE | PYROPTOSIS | IMMUNOLOGY | HOST-RESISTANCE | PROTECTS | Interleukin-18 - immunology | Caspases - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Chlamydia trachomatis - immunology | Interleukin-1beta - genetics | GTP-Binding Proteins - genetics | Chlamydia muridarum - immunology | Chlamydia Infections - immunology | Chlamydia Infections - pathology | Vacuoles - immunology | Chlamydia Infections - genetics | Inclusion Bodies - microbiology | Fibroblasts - microbiology | Interferon-gamma - genetics | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Chlamydia trachomatis - genetics | Inclusion Bodies - immunology | Vacuoles - microbiology | DNA-Binding Proteins - immunology | GTP-Binding Proteins - immunology | Signal Transduction | Caspases - genetics | Mice, Inbred C57BL | Chlamydia muridarum - genetics | Gene Expression Regulation | Interleukin-1beta - immunology | DNA-Binding Proteins - genetics | Inflammasomes - genetics | Mice, Knockout | Host-Pathogen Interactions | Carrier Proteins - genetics | Animals | Chlamydia Infections - microbiology | Chlamydia muridarum - pathogenicity | Inflammasomes - immunology | Interferon-gamma - immunology | Chlamydia trachomatis - pathogenicity | Fibroblasts - immunology | Mice | Primary Cell Culture | Interleukin-18 - genetics | Cellular Microbiology | Pathogen-Host Cell Molecular Interactions | Spotlight
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