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International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, ISSN 0020-7292, 01/2020
To determine whether participating in childbirth classes is associated with pregnancy outcomes. A retrospective study was conducted to review the medical... 
Journal Article
by Kim, SJ and Chun, M and Wan, JX and Lee, CH and Yen, K and Cohen, P
SCIENTIFIC REPORTS, ISSN 2045-2322, 04/2019, Volume 9, Issue 1, pp. 5546 - 9
Senescent cells that accumulate in multiple tissues with age are thought to increase pathological phenotypes. The removal of senescent cells can improve... 
CELLS | CLEARANCE | DNA METHYLATION | NONCODING RNAS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTIONAL REPRESSION | MODULATE | MITOCHONDRIAL-DNA | RNA-BINDING-PROTEIN | CELLULAR SENESCENCE | GENOME | Phenotypes | Senescence | Animal models | Nucleotide sequence | Ribonucleic acid--RNA | Doxorubicin | RNA-binding protein | Mitochondria | Life span | Fibroblasts | Aging | DNA methylation | Age | Deoxyribonucleic acid--DNA
Journal Article
Innovation in Aging, ISSN 2399-5300, 11/2019, Volume 3, Issue Supplement_1, pp. S940 - S940
Abstract The APOE4 allele is the greatest genetic risk factor for sporadic Alzheimer’s disease, yet select APOE4 carriers remain cognitively intact and become... 
Journal Article
Innovation in Aging, ISSN 2399-5300, 11/2019, Volume 3, Issue Supplement_1, pp. S555 - S555
Abstract We identified multiple open-reading-frames (ORFs) within the mitochondrial genome. These ORFs encode putative peptides that we call... 
Journal Article
Innovation in Aging, ISSN 2399-5300, 11/2019, Volume 3, Issue Supplement_1, pp. S838 - S838
Abstract Mitochondrial DNA (mtDNA) variants are associated with a wide range of diseases of aging, from diabetes to Alzheimer’s, as well as with longevity... 
Journal Article
08/2019
MOTS3 is a novel polypeptide. Methods of treating diseases such as diabetes, obesity, fatty liver, and cancer using MOTS3 and pharmaceutical compositions... 
METALLURGY | PEPTIDES | HYGIENE | PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES | ORGANIC CHEMISTRY | CHEMISTRY | MEDICAL OR VETERINARY SCIENCE | HUMAN NECESSITIES
Patent
Prostate cancer and prostatic diseases, ISSN 1365-7852, 08/2019
M2-like macrophages are associated with the pathogenesis of castrate-resistant prostate cancer (CRPC). We sought to determine if dietary omega-3 fatty acids... 
Journal Article
Physiological Reports, 07/2019, Volume 7, Issue 13, pp. e14171 - n/a
MOTS‐c is an exercise mimetic and improves insulin sensitivity in aged and diet‐induced obese mice. Although plasma markers are good markers for the metabolic... 
High‐fat diet | metabolomics | insulin resistance | MOTS‐c | Metabolomics | Obesity | Enzymes | Peptides | Liver | Body weight | Roles | Glucose | Metabolic syndrome | Insulin | Flexibility | Fatty acids | Musculoskeletal system | Osteoporosis | Mitochondria | Fatty liver | Metabolites | Diet | Insulin resistance | Oxidation | Diabetes | Lipid metabolism
Journal Article
07/2019
A user profile and messaging bots can be joined to participate in a group chat session. A first natural language requirement set can be received from the... 
ELECTRIC COMMUNICATION TECHNIQUE | TRANSMISSION OF DIGITAL INFORMATION, e.g. TELEGRAPHICCOMMUNICATION | COMPUTING | COUNTING | PHYSICS | ELECTRIC DIGITAL DATA PROCESSING | ELECTRICITY | CALCULATING
Patent
Metabolomics, ISSN 1573-3882, 6/2019, Volume 15, Issue 6, pp. 1 - 12
The mitochondrial-derived peptides (MDPs) are a novel group of natural occurring peptides that have important signaling functions and biological activity. Both... 
Life Sciences | Biochemistry, general | Biomedicine, general | Obesity | Mitochondrial-derived peptide | Aging | Insulin resistance | UPLC-MS/MS | Molecular Medicine | Sphingolipids | Developmental Biology | Cell Biology | Membrane lipids | Gerontology | Peptides | Metabolites | Analysis | Physiological aspects | Insulin | UPLC-MS | Original
Journal Article
European Journal of Paediatric Neurology, ISSN 1090-3798, 05/2019, Volume 23, Issue 3, pp. 418 - 426
The human WW Domain Containing Oxidoreductase (WWOX) gene was originally described as a tumor suppressor gene. However, recent reports have demonstrated its... 
Intellectual disability | Early infantile epileptic encephalopathy | 3′ splice site | WW Domain Containing Oxidoreductase | GENE | WW Domain Containing Oxidore-ductase | 3 ' splice site | PEDIATRICS | SPECTRUM | ATAXIA | CLINICAL NEUROLOGY | Jews | Encephalopathy
Journal Article
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