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Medecine sciences : M/S, 04/2019, Volume 35, Issue 4, p. 332
Recent progres in massive deep sequencing have paved the way to routine exploration of the current panorama of inherited predisposition to breast cancer,... 
Journal Article
M S-MEDECINE SCIENCES, ISSN 0767-0974, 02/2019, Volume 35, Issue 2, pp. 138 - 151
The main objective of oncogenetics is to characterize a subpopulation of patients at high risk of cancer development at an early age in order to provide... 
LI-FRAUMENI SYNDROME | MEDICINE, RESEARCH & EXPERIMENTAL | BRCA2 MUTATIONS | HISTOPATHOLOGICAL FEATURES | GASTRIC-CANCER | INCREASED RISK | GERMLINE MUTATIONS | PEUTZ-JEGHERS SYNDROME | OVARIAN-CANCER | ATM MUTATIONS | ATAXIA-TELANGIECTASIA
Journal Article
International Journal of Cancer, ISSN 0020-7136, 04/2019, Volume 144, Issue 8, pp. 1962 - 1974
Journal Article
Current Gene Therapy, ISSN 1566-5232, 04/2013, Volume 13, Issue 2, pp. 73 - 92
The unlimited proliferation capacity of embryonic stem cells (ESCs) combined with their pluripotent differentiation potential in various lineages raised great... 
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 4, pp. 1017 - 1029.e3
Background & Aims Patients with bi-allelic germline mutations in mismatch repair (MMR) genes ( MLH1 , MSH2 , MSH6 , or PMS2 ) develop a rare but severe variant... 
Gastroenterology and Hepatology | Tumor | Colon Cancer | Predisposition | Functional Tests | SYSTEM | CELLS | BIALLELIC MUTATIONS | SOMATIC MUTATIONS | HEREDITARY | COLORECTAL-CANCER | PMS2 | MSH6 MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | GOLD STANDARD | NEUROFIBROMATOSIS TYPE-1 | MutL Protein Homolog 1 | Predictive Value of Tests | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Drug Resistance, Neoplasm | Male | Neoplastic Syndromes, Hereditary - metabolism | Colorectal Neoplasms - diagnosis | Young Adult | DNA Mutational Analysis | Colorectal Neoplasms - drug therapy | Germ-Line Mutation | Mismatch Repair Endonuclease PMS2 | Neoplastic Syndromes, Hereditary - genetics | Caco-2 Cells | Lymphocytes - metabolism | Genetic Predisposition to Disease | Colorectal Neoplasms, Hereditary Nonpolyposis - drug therapy | Brain Neoplasms - diagnosis | HCT116 Cells | Brain Neoplasms - genetics | Neoplastic Syndromes, Hereditary - diagnosis | Heredity | MutS Homolog 2 Protein - genetics | Brain Neoplasms - drug therapy | Multiplex Polymerase Chain Reaction | Antineoplastic Agents, Alkylating - therapeutic use | Colorectal Neoplasms, Hereditary Nonpolyposis - metabolism | Phenotype | Adenosine Triphosphatases - genetics | Biomarkers, Tumor - genetics | Neoplastic Syndromes, Hereditary - drug therapy | Microsatellite Instability | Neoplastic Syndromes, Hereditary - pathology | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Genetic Testing - methods | Brain Neoplasms - metabolism | Case-Control Studies | Transfection | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Adult | Female | Nuclear Proteins - genetics | Colorectal Neoplasms - metabolism | Reproducibility of Results | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | DNA-Binding Proteins - genetics | Lymphocytes - drug effects | Adaptor Proteins, Signal Transducing - genetics | Colorectal Neoplasms - pathology | Methylation | Lymphomas | Diagnosis | Gene mutations | Lymphocytes | Leukemia | Colorectal cancer
Journal Article
Journal Article
by Sinilnikova, Olga M and Dondon, Marie-Gabrielle and Eon-Marchais, Séverine and Damiola, Francesca and Barjhoux, Laure and Marcou, Morgane and Verny-Pierre, Carole and Sornin, Valérie and Toulemonde, Lucie and Beauvallet, Juana and Le Gal, Dorothée and Mebirouk, Noura and Belotti, Muriel and Caron, Olivier and Gauthier-Villars, Marion and Coupier, Isabelle and Buecher, Bruno and Lortholary, Alain and Dugast, Catherine and Gesta, Paul and Fricker, Jean-Pierre and Noguès, Catherine and Faivre, Laurence and Luporsi, Elisabeth and Berthet, Pascaline and Delnatte, Capucine and Bonadona, Valérie and Maugard, Christine M and Pujol, Pascal and Lasset, Christine and Longy, Michel and Bignon, Yves-Jean and Adenis, Claude and Venat-Bouvet, Laurence and Demange, Liliane and Dreyfus, Hélène and Frenay, Marc and Gladieff, Laurence and Mortemousque, Isabelle and Audebert-Bellanger, Séverine and Soubrier, Florent and Giraud, Sophie and Lejeune-Dumoulin, Sophie and Chevrier, Annie and Limacher, Jean-Marc and Chiesa, Jean and Fajac, Anne and Floquet, Anne and Eisinger, François and Tinat, Julie and Colas, Chrystelle and Fert-Ferrer, Sandra and Penet, Clotilde and Frebourg, Thierry and Collonge-Rame, Marie-Agnès and Barouk-Simonet, Emmanuelle and Layet, Valérie and Leroux, Dominique and Cohen-Haguenauer, Odile and Prieur, Fabienne and Mouret-Fourme, Emmanuelle and Cornélis, François and Jonveaux, Philippe and Bera, Odile and Cavaciuti, Eve and Tardivon, Anne and Lesueur, Fabienne and Mazoyer, Sylvie and Stoppa-Lyonnet, Dominique and Andrieu, Nadine
BMC Cancer, ISSN 1471-2407, 01/2016, Volume 16, Issue 1, pp. 13 - 606
Journal Article
Bulletin du Cancer, ISSN 0007-4551, 10/2018, Volume 105, Issue 10, pp. 907 - 917
Introduction: Next generation sequencing allows the simultaneous analysis of large panel of genes for families or individuals with a strong suspicion of... 
Cancer genetics | Mutigene panels | Breast cancer | Genetic counseling | Guidelines | Ovarian cancer
Journal Article