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The Electricity Journal, ISSN 1040-6190, 07/2016, Volume 29, Issue 6, pp. 52 - 58
Journal Article
The Journal of Clinical Pharmacology, ISSN 0091-2700, 08/2018, Volume 58, Issue 8, pp. 1067 - 1073
The primary objective of this phase 1, open‐label, multicenter, 3‐period, fixed‐sequence study was to evaluate the effect of multiple doses of vemurafenib on... 
pharmacokinetics | vemurafenib | drug‐drug interactions | P‐glycoprotein | digoxin | P-glycoprotein | drug-drug interactions | Statistical analysis | Digoxin | Drug interactions | Glycoprotein | Pharmacology | Malignancy | Metastasis | Variance analysis | Patients | Substrates | Metastases | Drug interaction | In vivo methods and tests | Mutation | Pharmacokinetics | Drug dosages
Journal Article
British Journal of Haematology, ISSN 0007-1048, 2018, Volume 185, Issue 3, pp. 595 - 598
Table S3. Adverse events of all grades occurring in a[yen]20% of all treated patients. 
stem cells | leukaemia | vismodegib | Hedgehog signalling | MALIGNANCIES | HEMATOLOGY | Clinical trials | Stem cells | Vismodegib | Refractory materials | Leukemia
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 07/2017, Volume 80, Issue 1, pp. 29 - 36
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 7/2016, Volume 78, Issue 1, pp. 41 - 49
The Hedgehog pathway inhibitor vismodegib exhibits pH-dependent solubility, and in vitro studies have shown that vismodegib is a substrate of P-glycoprotein... 
Medicine & Public Health | CYP inhibitors | Clinical pharmacology | Oncology | Cancer Research | Pharmacology/Toxicology | Clinical drug–drug interaction | Pharmacokinetic | Proton-pump inhibitor | P-glycoprotein inhibitor | SINGLE | HUMAN PLASMA | ORAL ABSORPTION | MASS-SPECTROMETRY | GDC-0449 | ONCOLOGY | Clinical drug-drug interaction | PHARMACOLOGY & PHARMACY | HEALTHY-VOLUNTEERS | HEDGEHOG SIGNALING PATHWAY | SOLID-PHASE EXTRACTION | Fluconazole - pharmacology | Proton Pump Inhibitors - pharmacology | Cytochrome P-450 CYP3A Inhibitors - administration & dosage | Pyridines - administration & dosage | Cytochrome P-450 CYP3A Inhibitors - pharmacology | Area Under Curve | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Fluconazole - administration & dosage | Solubility | Pyridines - pharmacokinetics | Anilides - pharmacokinetics | ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors | Itraconazole - pharmacology | Cytochrome P-450 CYP2C9 Inhibitors - administration & dosage | Cytochrome P-450 CYP2C9 Inhibitors - pharmacology | Drug Interactions | Anilides - administration & dosage | Proton Pump Inhibitors - administration & dosage | Rabeprazole - pharmacology | Female | Itraconazole - administration & dosage | Hydrogen-Ion Concentration | Rabeprazole - administration & dosage | Drug interactions | Cytochrome P-450 | Index Medicus | Original
Journal Article
Journal of clinical pharmacology, ISSN 0091-2700, 04/2018, Volume 58, Issue 8, pp. 1067 - 1073
The primary objective of this phase 1, open-label, multicenter, 3-period, fixed-sequence study was to evaluate the effect of multiple doses of vemurafenib on... 
Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 1/2013, Volume 71, Issue 1, pp. 193 - 202
Vismodegib, a first-in-class oral hedgehog pathway inhibitor, is an effective treatment for advanced basal cell carcinoma. Based on in vitro data, a clinical... 
Medicine & Public Health | Erivedge | Drug–drug interaction | Rosiglitazone | Oncology | Cancer Research | Oral contraceptive | Vismodegib | Pharmacology/Toxicology | Drug-drug interaction | SONIC HEDGEHOG | Erivedge (TM) | CANCER | GDC-0449 | FEMALE SUBJECTS | METABOLISM | ONCOLOGY | MEDULLOBLASTOMAS | PHARMACOLOGY & PHARMACY | MUTATIONS | INHIBITOR | HUMAN HOMOLOG | HEDGEHOG SIGNALING PATHWAY | Cytochrome P-450 CYP2C8 | Ethinyl Estradiol - pharmacokinetics | Area Under Curve | Contraceptives, Oral, Combined - pharmacokinetics | Humans | Middle Aged | Pyridines - pharmacokinetics | Male | Anilides - pharmacokinetics | Antineoplastic Agents - administration & dosage | Norethindrone - administration & dosage | Thiazolidinediones - pharmacokinetics | Neoplasm Metastasis | Drug Interactions | Norethindrone - pharmacokinetics | Female | Antineoplastic Agents - pharmacokinetics | Antineoplastic Agents - pharmacology | Ethinyl Estradiol - administration & dosage | Contraceptives, Oral, Combined - administration & dosage | Pyridines - administration & dosage | Aryl Hydrocarbon Hydroxylases - drug effects | Aryl Hydrocarbon Hydroxylases - metabolism | Neoplasms - drug therapy | Anilides - administration & dosage | Cytochrome P-450 CYP3A - metabolism | Anilides - pharmacology | Aged | Pyridines - pharmacology | Neoplasms - pathology | Cohort Studies | Complications and side effects | Analysis | Drug interactions | Cytochrome P-450 | Ethinyl estradiol | Metastasis | Oral contraceptives | Thiazolidinediones | Skin cancer | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 08/2015, Volume 75, Issue 15 Supplement, pp. CT308 - CT308
Journal Article
Journal Article
Journal of Applied Social Psychology, ISSN 0021-9029, 10/2008, Volume 38, Issue 10, pp. 2495 - 2517
The present study examined relationships between the variables of depression, shame, guilt, psychological maltreatment, and dispositional forgiveness. The... 
DEPRESSION | PSYCHOLOGY, SOCIAL | PSYCHOLOGICAL MALTREATMENT | INDIVIDUAL-DIFFERENCES | GUILT | ABUSE | SHAME | SELF | ANGER ATTACKS | CHILDHOOD | ASSOCIATION | Emotional abuse
Journal Article
Journal of Thoracic Oncology, ISSN 1556-0864, 09/2014, Volume 9, Issue 9, pp. 1411 - 1417
Journal Article
Cancer, ISSN 0008-543X, 07/2001, Volume 92, Issue 2, pp. 406 - 413
Journal Article