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Cancer Discovery, ISSN 2159-8274, 09/2018, Volume 8, Issue 9, pp. 1062 - 1063
Two articles in this issue of Cancer Discovery show that deep profiling of advanced pancreatic cancer is feasible and identify many clinically actionable... 
ONCOLOGY
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 06/2015, Volume 21, Issue 11, pp. 2418 - 2420
The treatment of resected lung adenocarcinoma has ample room for improvement. Can genomic characterization aid us in deciding how and when to apply adjuvant... 
ONCOLOGY | CANCER | ASSAY | Lung Neoplasms - genetics | Retinoblastoma Protein - genetics | Genomics | Humans | Female | Male | Adenocarcinoma - genetics | DNA Copy Number Variations - genetics
Journal Article
by Hammerman, Peter S and Voet, Doug and Lawrence, Michael S and Voet, Doug and Jing, Rui and Cibulskis, Kristian and Sivachenko, Andrey and Stojanov, Petar and McKenna, Aaron and Lander, Eric S and Gabriel, Stacey and Getz, Gad and Imielinski, Marcin and Helman, Elena and Hernandez, Bryan and Pho, Nam H and Meyerson, Matthew and Chu, Andy and Hye-Chun, Jung E and Mungall, Andrew J and Pleasance, Erin and Robertson, A. Gordon and Sipahimalani, Payal and Stoll, Dominik and Balasundaram, Miruna and Birol, Inanc and Butterfield, Yaron S.N and Chuah, Eric and Coope, Robin J.N and Corbett, Richard and Dhalla, Noreen and Guin, Ranabir and He, An and Hirst, Carrie and Hirst, Martin and Holt, Robert A and Lee, Darlene and Li, Haiyan I and Mayo, Michael and Moore, Richard A and Mungall, Karen and Nip, Ka Ming and Olshen, Adam and Schein, Jacqueline E and Slobodan, Jared R and Tam, Angela and Thiessen, Nina and Varhol, Richard and Zeng, Thomas and Zhao, Yongjun and Jones, Steven J.M and Marra, Marco A and Saksena, Gordon and Cherniack, Andrew D and Schumacher, Stephen E and Tabak, Barbara and Carter, Scott L and Nguyen, Huy and Onofrio, Robert C and Crenshaw, Andrew and Ardlie, Kristin and Beroukhim, Rameen and Winckler, Wendy and Protopopov, Alexei and Zhang, Jianhua and Hadjipanayis, Angela and Lee, Semin and Xi, Ruibin and Yang, Lixing and Ren, Xiaojia and Zhang, Hailei and Shukla, Sachet and Chen, Peng-Chieh and Haseley, Psalm and Lee, Eunjung and Chin, Lynda and Park, Peter J and Kucherlapati, Raju and Socci, Nicholas D and Liang, Yupu and Schultz, Nikolaus and Borsu, Laetitia and Lash, Alex E and Viale, Agnes and Sander, Chris and Ladanyi, Marc and Auman, J. Todd and Hoadley, Katherine A and Wilkerson, Matthew D and Shi, Yan and Liquori, Christina and Meng, Shaowu and Li, Ling and Turman, Yidi J and Topal, Michael D and Tan, Donghui and Waring, Scot and Buda, Elizabeth and Walsh, Jesse and Jones, Corbin D and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and The Cancer Genome Atlas Research Network
Nature, ISSN 0028-0836, 09/2012, Volume 489, Issue 7417, pp. 519 - 525
Journal Article
by Collisson, Eric A and Campbell, Joshua D and Brooks, Angela N and Berger, Alice H and Lee, William and Chmielecki, Juliann and Beer, David G and Cope, Leslie and Creighton, Chad J and Danilova, Ludmila and Ding, Li and Getz, Gad and Hammerman, Peter S and Hayes, D. Neil and Hernandez, Bryan and Herman, James G and Heymach, John V and Jurisica, Igor and Kucherlapati, Raju and Kwiatkowski, David and Ladanyi, Marc and Robertson, Gordon and Schultz, Nikolaus and Shen, Ronglai and Sinha, Rileen and Sougnez, Carrie and Tsao, Ming-Sound and Travis, William D and Weinstein, John N and Wigle, Dennis A and Wilkerson, Matthew D and Chu, Andy and Cherniack, Andrew D and Hadjipanayis, Angela and Rosenberg, Mara and Weisenberger, Daniel J and Laird, Peter W and Radenbaugh, Amie and Ma, Singer and Stuart, Joshua M and Byers, Lauren Averett and Baylin, Stephen B and Govindan, Ramaswamy and Meyerson, Matthew and Gabriel, Stacey B and Cibulskis, Kristian and Kim, Jaegil and Stewart, Chip and Lichtenstein, Lee and Lander, Eric S and Lawrence, Michael S and Getz, E and Fulton, Robert and Fulton, Lucinda L and McLellan, Michael D and Wilson, Richard K and Ye, Kai and Fronick, Catrina C and Maher, Christopher A and Miller, Christopher A and Wendl, Michael C and Cabanski, Christopher and Mardis, Elaine and Wheeler, David and Balasundaram, Miruna and Butterfield, Yaron S. N and Carlsen, Rebecca and Chuah, Eric and Dhalla, Noreen and Guin, Ranabir and Hirst, Carrie and Lee, Darlene and Li, Haiyan I and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Varhol, Richard and Robertson, A. Gordon and Wye, Natasja and Thiessen, Nina and Holt, Robert A and Jones, Steven J.M and Marra, Marco A and Imielinski, Marcin and Onofrio, Robert C and Hodis, Eran and Zack, Travis and Helman, Elena and Pedamallu, Chandra Sekhar and Mesirov, Jill and Saksena, Gordon and Schumacher, Steven E and Carter, Scott L and Garraway, Levi and Beroukhim, Rameen and Lee, Semin and Mahadeshwar, Harshad S and ...
Nature, ISSN 0028-0836, 2014, Volume 511, Issue 7511, pp. 543 - 550
Journal Article
by Weinstein, John N and Collisson, Eric A and Mills, Gordon B and Shaw, Kenna R Mills and Ozenberger, Brad A and Ellrott, Kyle and Sander, Chris and Stuart, Joshua M and Chang, Kyle and Creighton, Chad J and Davis, Caleb and Donehower, Lawrence and Drummond, Jennifer and Wheeler, David and Ally, Adrian and Balasundaram, Miruna and Birol, Inanc and Butterfield, Yaron S.N and Chu, Andy and Chuah, Eric and Chun, Hye-Jung E and Dhalla, Noreen and Guin, Ranabir and Hirst, Martin and Hirst, Carrie and Holt, Robert A and Jones, Steven J.M and Lee, Darlene and Li, Haiyan I and Marra, Marco A and Mayo, Michael and Moore, Richard A and Mungall, Andrew J and Robertson, A Gordon and Schein, Jacqueline E and Sipahimalani, Payal and Tam, Angela and Thiessen, Nina and Varhol, Richard J and Beroukhim, Rameen and Bhatt, Ami S and Brooks, Angela N and Cherniack, Andrew D and Freeman, Samuel S and Gabriel, Stacey B and Helman, Elena and Jung, Joonil and Meyerson, Matthew and Ojesina, Akinyemi I and Pedamallu, Chandra Sekhar and Saksena, Gordon and Schumacher, Steven E and Tabak, Barbara and Zack, Travis and Lander, Eric S and Bristow, Christopher A and Hadjipanayis, Angela and Haseley, Psalm and Kucherlapati, Raju and Lee, Semin and Lee, Eunjung and Luquette, Lovelace J and Mahadeshwar, Harshad S and Pantazi, Angeliki and Parfenov, Michael and Park, Peter J and Protopopov, Alexei and Ren, Xiaojia and Santoso, Netty and Seidman, Jonathan and Seth, Sahil and Song, Xingzhi and Tang, Jiabin and Xi, Ruibin and Xu, Andrew W and Yang, Lixing and Zeng, Dong and Auman, J Todd and Balu, Saianand and Buda, Elizabeth and Fan, Cheng and Hoadley, Katherine A and Jones, Corbin D and Meng, Shaowu and Mieczkowski, Piotr A and Parker, Joel S and Perou, Charles M and Roach, Jeffrey and Shi, Yan and Silva, Grace O and Tan, Donghui and Veluvolu, Umadevi and Waring, Scot and Wilkerson, Matthew D and Wu, Junyuan and Zhao, Wei and Bodenheimer, Tom and Hayes, D Neil and Hoyle, Alan P and Jeffreys, Stuart R and ... and Canc Genome Atlas Res Network and Cancer Genome Atlas Research Network and The Cancer Genome Atlas Research Network and Department of Mathematical Sciences, Mathematical Statistics and Naturvetenskapliga fakulteten and Institutionen för matematiska vetenskaper, matematisk statistik and Faculty of Sciences and Göteborgs universitet and Gothenburg University
Nature Genetics, ISSN 1061-4036, 10/2013, Volume 45, Issue 10, pp. 1113 - 1120
The Cancer Genome Atlas (TCGA) Research Network has profiled and analyzed large numbers of human tumors to discover molecular aberrations at the DNA, RNA,... 
ONCOGENE | FUSION | GENE | GENETICS & HEREDITY | MUTATIONS | IDENTIFICATION | HALLMARKS | Gene Expression Profiling | Neoplasms - genetics | Genome | Neoplasms - pathology | Humans | Medical research | Breast cancer | Mutation | Genomics | Tumors | Genetik | Medicinsk genetik | Medical Genetics | Genetics
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2015, Volume 10, Issue 10, p. e0140712
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 05/2012, Volume 25, Issue 3, pp. 292 - 293
Journal Article
Nature Genetics, ISSN 1061-4036, 02/2015, Volume 47, Issue 3, pp. 250 - 256
Resistance to RAF-and MEK-targeted therapy is a major clinical challenge(1-4). RAF and MEK inhibitors are initially but only transiently effective in some but... 
COLON-CANCER | SURVIVAL | LUNG | ACTIVATION | INHIBITION | MELANOMA | SIGNALING PATHWAY | TRANSCRIPTION | GENETICS & HEREDITY | BRAF | KRAS | Humans | Molecular Targeted Therapy | Phosphoproteins - metabolism | Gene Knockdown Techniques | Heterografts | MAP Kinase Signaling System - genetics | HEK293 Cells | Female | MAP Kinase Kinase Kinases - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Proto-Oncogene Proteins B-raf - metabolism | MAP Kinase Kinase Kinases - genetics | Protein-Serine-Threonine Kinases - genetics | MAP Kinase Kinase Kinases - metabolism | Phosphoproteins - genetics | Mice, SCID | HT29 Cells | Proto-Oncogene Proteins B-raf - antagonists & inhibitors | Drug Resistance, Neoplasm - genetics | Animals | MAP Kinase Signaling System - drug effects | Proto-Oncogene Proteins B-raf - genetics | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Protein Kinase Inhibitors - pharmacology | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Genes, ras | Antimitotic agents | Gene mutations | Genetic aspects | Research | Antineoplastic agents | Drug resistance | Health aspects | Thyroid cancer | Lung cancer | Colorectal cancer | Melanoma | Kinases | Charitable foundations | Cancer therapies | Design of experiments | Tumors
Journal Article
Journal Article