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Diabetes, ISSN 0012-1797, 04/2008, Volume 57, Issue 4, pp. 1084 - 1092
Journal Article
The EMBO Journal, ISSN 0261-4189, 12/2006, Volume 25, Issue 24, pp. 5775 - 5782
The phosphatidyl inositol 3‐kinase‐like kinases (PIKKs), ataxia‐telangiectasia mutated (ATM) and ATM‐ and Rad3‐related (ATR) regulate parallel damage response... 
ataxia telangiectasia‐mutated protein | PIKKs | phosphorylation | DNA damage responses | Phosphorylation | Ataxia telangiectasia-mutated protein | RECRUITMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | ataxia telangiectasia-mutated protein | DNA-DAMAGE | COMPLEXES | PROTEIN-KINASES | CELL BIOLOGY | CHK1 | SECKEL-SYNDROME | CHECKPOINT | IONIZING-RADIATION | ATAXIA-TELANGIECTASIA | BINDING | Protein Kinases - metabolism | Hydroxyurea - pharmacology | Protein-Serine-Threonine Kinases - deficiency | DNA Replication - drug effects | Humans | G2 Phase - drug effects | DNA-Binding Proteins - metabolism | Ultraviolet Rays | DNA Replication - radiation effects | Phosphorylation - drug effects | Protein-Serine-Threonine Kinases - metabolism | Protein Structure, Tertiary | Tumor Suppressor Proteins - metabolism | Mitosis - radiation effects | G2 Phase - radiation effects | Cell Cycle Proteins - metabolism | Nuclear Proteins - metabolism | Ataxia Telangiectasia Mutated Proteins | Enzyme Activation - drug effects | Fibroblasts - pathology | Phosphoserine - metabolism | Enzyme Activation - radiation effects | Histones - deficiency | Phosphorylation - radiation effects | Animals | Mitosis - drug effects | Fibroblasts - radiation effects | Models, Biological | Fibroblasts - drug effects | Phosphoproteins - deficiency | Checkpoint Kinase 2 | Checkpoint Kinase 1 | Fibroblasts - cytology | Mice | Ions | Ultraviolet radiation | Molecular biology | Kinases | DNA damage | Index Medicus
Journal Article
Nature Genetics, ISSN 1061-4036, 12/2012, Volume 44, Issue 12, pp. 1336 - 1340
Journal Article
by Okada, Yukinori and Wu, Di and Trynka, Gosia and Raj, Towfique and Terao, Chikashi and Ikari, Katsunori and Kochi, Yuta and Ohmura, Koichiro and Suzuki, Akari and Yoshida, Shinji and Graham, Robert R and Manoharan, Arun and Ortmann, Ward and Bhangale, Tushar and Denny, Joshua C and Carroll, Robert J and Eyler, Anne E and Greenberg, Jeffrey D and Kremer, Joel M and Pappas, Dimitrios A and Jiang, Lei and Yin, Jian and Ye, Lingying and Su, Ding-Feng and Yang, Jian and Xie, Gang and Keystone, Ed and Westra, Harm-Jan and Esko, Tõnu and Metspalu, Anes and Zhou, Xuezhong and Gupta, Namrata and Mirel, Daniel and Stahl, Eli A and Diogo, Dorothée and Cui, Jing and Liao, Katherine and Guo, Michael H and Myouzen, Keiko and Kawaguchi, Takahisa and Coenen, Marieke J. H and van Riel, Piet L. C. M and van de Laar, Mart A. F. J and Guchelaar, Henk-Jan and Huizinga, Tom W. J and Dieudé, Philippe and Mariette, Xavier and Bridges, S. Louis and Zhernakova, Alexana and Toes, Rene E. M and Tak, Paul P and Miceli-Richard, Corinne and Bang, So-Young and Lee, Hye-Soon and Martin, Javier and Gonzalez-Gay, Miguel A and Roiguez-Roiguez, Luis and Rantapää-Dahlqvist, Solbritt and Arlestig, Lisbeth and Choi, Hyon K and Kamatani, Yoichiro and Galan, Pilar and Lathrop, Mark and Eyre, Steve and Bowes, John and Barton, Anne and de Vries, Niek and Moreland, Larry W and Criswell, Lindsey A and Karlson, Elizabeth W and Taniguchi, Atsuo and Yamada, Ryo and Kubo, Michiaki and Liu, Jun S and Bae, Sang-Cheol and Worthington, Jane and Padyukov, Leonid and Klareskog, Lars and Gregersen, Peter K and Raychaudhuri, Soumya and Stranger, Barbara E and de Jager, Philip L and Franke, Lude and Visscher, Peter M and Brown, Matthew A and Yamanaka, Hisashi and Mimori, Tsuneyo and Takahashi, Atsushi and Xu, Huji and Behrens, Timothy W and Siminovitch, Katherine A and Momohara, Shigeki and Matsuda, Fumihiko and Yamamoto, Kazuhiko and Plenge, Robert M and Lee, Annette and Martin, Paul and Stahl, Eli and Viatte, Sebastien and McAllister, Kate and ... and RACI Consortium and GARNET Consortium and RACI consortium and GARNET consortium and the RACI consortium and the GARNET consortium and Medicinska fakulteten and Institutionen för folkhälsa och klinisk medicin and Umeå universitet and Reumatologi
Nature, ISSN 0028-0836, 2014, Volume 506, Issue 7488, pp. 376 - +
A major challenge in human genetics is to devise a systematic strategy to integrate disease-associated variants with diverse genomic and biological data sets... 
RECEPTOR INHIBITION | VARIANTS | MULTIDISCIPLINARY SCIENCES | DISEASE | SUSCEPTIBILITY | RISK | LOCI | IDENTIFICATION | TRAITS | GENOME-WIDE ASSOCIATION | RESOURCE | European Continental Ancestry Group - genetics | Genetic Predisposition to Disease - genetics | Genome-Wide Association Study | Humans | Asian Continental Ancestry Group - genetics | Computational Biology | Male | Drug Repositioning | Molecular Targeted Therapy | Drug Discovery | Case-Control Studies | Arthritis, Rheumatoid - pathology | Mice, Knockout | Arthritis, Rheumatoid - metabolism | Arthritis, Rheumatoid - genetics | Animals | Arthritis, Rheumatoid - drug therapy | Alleles | Polymorphism, Single Nucleotide - genetics | Female | Hematologic Neoplasms - genetics | Mice | Hematologic Neoplasms - metabolism | Quantitative trait loci | Genome-wide association studies | Rheumatoid arthritis | Genetic research | Genetic aspects | Research | Human genetics | Disease | Hematology | Cytokines | Genes | Genomics | Genomes | Meta-analysis | Proteins | Confidence intervals | Hypotheses | Quality control | Epigenetics | Population | Genetics | Health risk assessment | Asians | Cancer | Index Medicus | Rheumatology and Autoimmunity | Clinical Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Reumatologi och inflammation | Virtual screening | Klinisk medicin
Journal Article
by Do, Ron and Stitziel, Nathan O and Won, Hong-Hee and Jørgensen, Anders Berg and Duga, Stefano and Angelica Merlini, Pier and Kiezun, Adam and Farrall, Martin and Goel, Anuj and Zuk, Or and Guella, Illaria and Asselta, Rosanna and Lange, Leslie A and Peloso, Gina M and Auer, Paul L and Girelli, Domenico and Martinelli, Nicola and Farlow, Deborah N and DePristo, Mark A and Roberts, Robert and Stewart, Alexander F. R and Saleheen, Danish and Danesh, John and Epstein, Stephen E and Sivapalaratnam, Suthesh and Hovingh, G. Kees and Kastelein, John J and Samani, Nilesh J and Schunkert, Heribert and Erdmann, Jeanette and Shah, Svati H and Kraus, William E and Davies, Robert and Nikpay, Majid and Johansen, Christopher T and Wang, Jian and Hegele, Robert A and Hechter, Eliana and Marz, Winfried and Kleber, Marcus E and Huang, Jie and Johnson, Anew D and Li, Mingyao and Burke, Greg L and Gross, Myron and Liu, Yongmei and Assimes, Themistocles L and Heiss, Gerardo and Lange, Ethan M and Folsom, Aaron R and Taylor, Herman A and Olivieri, Oliviero and Hamsten, Anders and Clarke, Robert and Reilly, Dermot F and Yin, Wu and Rivas, Manuel A and Donnelly, Peter and Rossouw, Jacques E and Psaty, Bruce M and Herrington, David M and Wilson, James G and Rich, Stephen S and Bamshad, Michael J and Tracy, Russell P and Cupples, L. Aienne and Rader, Daniel J and Reilly, Muredach P and Spertus, John A and Cresci, Sharon and Hartiala, Jaana and Tang, W. H. Wilson and Hazen, Stanley L and Allayee, Hooman and Reiner, Alex P and Carlson, Christopher S and Kooperberg, Charles and Jackson, Rebecca D and Boerwinkle, Eric and Lander, Eric S and Schwartz, Stephen M and Siscovick, David S and McPherson, Ruth and Tybjaerg-Hansen, Anne and Abecasis, Goncalo R and Watkins, Hugh and Nickerson, Deborah A and Ardissino, Diego and Sunyaev, Shamil R and O'Donnell, Christopher J and Altshuler, David and Gabriel, Stacey and Kathiresan, Sekar and Gabriel, Stacey B and Altshuler, David M and Abecasis, Gonçalo R and Daly, Mark J and de Bakker, Paul I. W and Fennell, Tim and Garimella, Kiran and ... and NHLBI Exome Sequencing Project
Nature, ISSN 0028-0836, 2015, Volume 518, Issue 7537, pp. 102 - +
Journal Article
Journal Article