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Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2012, Volume 109, Issue 41, pp. 16570 - 16575
MicroRNAs (miRNAs) have an important role in the development of chemosensitivity or chemoresistance in different types of cancer. Activation of the ERK1/2... 
Up regulation | MicroRNA | Transfection | Cell lines | Gene expression regulation | Down regulation | Apoptosis | Tumors | Application programming interfaces | Lung neoplasms | Noncoding small RNA | Drug resistance | PROTEIN-KINASE-C | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | PROLIFERATION | PEA-15 | MICRORNA-494 | noncoding small RNA | ASTROCYTES | PED/PEA-15 | PATHWAY | RESISTANCE | CHRONIC LYMPHOCYTIC-LEUKEMIA | drug resistance | Cell Proliferation | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Apoptosis - genetics | Lung Neoplasms - pathology | Male | Gene Expression Profiling | MAP Kinase Signaling System - genetics | TNF-Related Apoptosis-Inducing Ligand - pharmacology | Bcl-2-Like Protein 11 | RNA Interference | Mitogen-Activated Protein Kinase 1 - genetics | HEK293 Cells | Apoptosis Regulatory Proteins - genetics | Tumor Burden - genetics | Membrane Proteins - metabolism | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Mitogen-Activated Protein Kinase 3 - genetics | Carcinoma, Non-Small-Cell Lung - genetics | Membrane Proteins - genetics | Down-Regulation | Carcinoma, Non-Small-Cell Lung - metabolism | Proto-Oncogene Proteins - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Apoptosis Regulatory Proteins - metabolism | Xenograft Model Antitumor Assays | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Mice, Nude | Cell Line, Tumor | Mice | MicroRNAs - genetics | Mitogen-Activated Protein Kinase 1 - metabolism | Lung cancer | Physiological aspects | Development and progression | Genetic aspects | Metastasis | Research | Health aspects | Phosphotransferases | Cancer | Biological Sciences
Journal Article
American Heart Journal, ISSN 0002-8703, 2015, Volume 173, pp. 67 - 76
Journal Article
Nature Medicine, ISSN 1078-8956, 01/2012, Volume 18, Issue 1, pp. 74 - 82
Journal Article
Lancet, The, ISSN 0140-6736, 2014, Volume 383, Issue 9931, pp. 1786 - 1788
  According to Frank-Starling curves, in ventricles with normal cardiac performance, a steep and positive association exists between increased left ventricular... 
Internal Medicine | SYSTEM | PREVENTION | MEDICINE, GENERAL & INTERNAL | INDUCED NEPHROPATHY | FUROSEMIDE | PREDICTION | Female | Male | Contrast Media - adverse effects | Fluid Therapy - methods | Humans | Acute Kidney Injury - prevention & control | Urine | Contrast agents | Medical imaging | Kidneys | Hydration | Rodents | Mortality | Blood pressure | Patients
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e74466
Glioblastoma multiforme (GBM) is one of the most deadly types of cancer. To date, the best clinical approach for treatment is based on administration of... 
OVEREXPRESSION | GLIOBLASTOMA | PROMOTER METHYLATION | MULTIDISCIPLINARY SCIENCES | MALIGNANT GLIOMAS | MICE | MICRORNAS | O-6-METHYLGUANINE-DNA METHYLTRANSFERASE | CANCER | TUMORIGENESIS | ADJUVANT TEMOZOLOMIDE | DNA Damage - drug effects | Humans | RNA, Messenger - genetics | DNA Repair Enzymes - genetics | Gene Expression Regulation, Neoplastic | Antineoplastic Agents, Alkylating - pharmacology | Apoptosis - genetics | Glioma - metabolism | Glioma - genetics | DNA Modification Methylases - genetics | Drug Resistance, Neoplasm - genetics | RNA Interference | Dacarbazine - pharmacology | Tumor Suppressor Proteins - genetics | Dacarbazine - analogs & derivatives | Cell Line, Tumor | DNA Damage - genetics | MicroRNAs - genetics | Temozolomide | MicroRNA | Gliomas | Cell death | DNA damage | Transferases | DNA | Genetic aspects | Methylation | Cancer | Biotechnology | Brain tumors | Glioblastoma | mRNA | Kinases | Chromosome rearrangements | Cancer therapies | DNA repair | Alkylation | O6-methylguanine-DNA methyltransferase | Proteins | Rodents | Glioma cells | Penicillin | DNA methylation | Tumorigenesis | Damage | Deoxyribonucleic acid--DNA | Enzymes | Methylguanine | MiRNA | Cell division | Radiation therapy | Forensic medicine | Gene expression | Ribonucleic acid--RNA | Patients | Glioblastoma multiforme | Pathology | MicroRNAs | Medical prognosis | Regulatory mechanisms (biology) | Epigenetics | DNA methyltransferase | Chromosome aberrations | Tumors | Apoptosis | Càncer | Glioma | ADN | Micro RNAs | RNA | Deoxyribonucleic acid | Ribonucleic acid
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 9, p. e24071
Nucleic acid aptamers have been developed as high-affinity ligands that may act as antagonists of disease-associated proteins. Aptamers are non immunogenic and... 
LUNG-CANCER | INDUCED ACTIVATION | CETUXIMAB | TARGETED THERAPIES | EPIDERMAL-GROWTH-FACTOR | BIOLOGY | RESISTANCE | ERBB SIGNALING NETWORK | TYROSINE KINASES | TUMOR-CELLS | FACTOR RECEPTOR | Aptamers, Nucleotide - pharmacology | Cell Survival - drug effects | Lung Neoplasms - drug therapy | Caspase 9 - metabolism | Apoptosis - drug effects | Humans | Lung Neoplasms - metabolism | Caspase 3 - metabolism | Caspase 8 - metabolism | Antibodies, Monoclonal - therapeutic use | Aptamers, Nucleotide - therapeutic use | Drug Resistance, Neoplasm | Immunoblotting | Antineoplastic Agents - therapeutic use | Antibodies, Monoclonal, Humanized | Receptor, Epidermal Growth Factor - metabolism | Animals | Flow Cytometry | Mice, Nude | Cell Line, Tumor | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Mice | Cetuximab | Tyrosine | Biological products | Epidermal growth factor | RNA | Gliomas | Monoclonal antibodies | Biochemistry | Lung cancer, Non-small cell | Apoptosis | Drugs | Toxicity | Biological evolution | Brain tumors | Lung cancer | Antagonists | Drug delivery | Neuroblastoma | Drug development | Kinases | Cancer therapies | Cell surface | Proteins | Xenografts | Biocompatibility | Nuclease | Gefitinib | Protein-tyrosine kinase | Decoys | Epidermal growth factor receptors | Non-small cell lung carcinoma | Breast cancer | FDA approval | Ribonucleic acid--RNA | Inhibitors | Glioma | Immunogenicity | Cell death | Medical prognosis | Neutralizing | Aptamers | Ligands | Combined treatment | Mutation | Gene therapy | Tumors | Cancer | Ribonucleic acid
Journal Article
Analytical and Bioanalytical Chemistry, ISSN 1618-2642, 1/2013, Volume 405, Issue 2, pp. 1025 - 1034
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 11, p. e27722
Many studies have shown that microRNA expression in cancer may be regulated by epigenetic events. Recently, we found that in lung cancer miR-212 was strongly... 
APOPTOSIS | DNA METHYLATION | TRAIL RESISTANCE | MULTIDISCIPLINARY SCIENCES | GROWTH | INHIBITOR | TRICHOSTATIN-A | MICRORNA SIGNATURES | Apoptosis - drug effects | CpG Islands - drug effects | Humans | Middle Aged | Transcription Initiation Site - drug effects | Apoptosis - genetics | Lung Neoplasms - pathology | Male | Promoter Regions, Genetic - drug effects | Promoter Regions, Genetic - genetics | Histone-Lysine N-Methyltransferase - antagonists & inhibitors | Aged, 80 and over | Female | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Gene Expression Regulation, Neoplastic - genetics | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | DNA-Binding Proteins - antagonists & inhibitors | Carcinoma, Non-Small-Cell Lung - genetics | Gene Silencing | Histocompatibility Antigens | Histone Deacetylases - metabolism | Transcription Factors - antagonists & inhibitors | DNA Methylation - genetics | Enhancer of Zeste Homolog 2 Protein | Acetylation - drug effects | Polycomb Repressive Complex 2 | Cell Line, Tumor | CpG Islands - genetics | Histone Deacetylase Inhibitors - pharmacology | Aged | MicroRNAs - genetics | Histones - metabolism | Neoplasm Staging | DNA Methylation - drug effects | Lung cancer, Non-small cell | Epigenetic inheritance | MicroRNA | Biomedical research | Leukemia | Lung cancer | MiRNA | Non-small cell lung carcinoma | Metastasis | Forensic medicine | Gene expression | Ribonucleic acid--RNA | Stomach cancer | Proteins | Pathology | Molecular modelling | MicroRNAs | Pancreatic cancer | Medical prognosis | DNA methylation | Epigenetics | Molecular biology | Growth factors | Deoxyribonucleic acid--DNA | Cancer | RNA | Ribonucleic acid | Deoxyribonucleic acid | DNA
Journal Article
Cancers, ISSN 2072-6694, 10/2019, Volume 11, Issue 10, p. 1521
Due to the progress made in the area of precision and personalized medicine in the field of cancer therapy, strategies to selectively and specifically identify... 
rnai | cancer therapy | brain tumors | shrna | mirna | sirna | targeted delivery | diagnosis | aso | aptamers
Journal Article
Faraday discussions, ISSN 1359-6640, 12/2017, Volume 205, pp. 271 - 289
In this work, SERS-based microfluidic PDMS chips integrating silver-coated porous silicon membranes were used for the detection and quantitation of microRNAs... 
Limit of Detection | Nucleic Acid Hybridization | MicroRNAs - analysis | Humans | Metal Nanoparticles - chemistry | Silver - chemistry | Cell Line, Tumor | Nanostructures - chemistry | Lab-On-A-Chip Devices | Spectrum Analysis, Raman - methods
Journal Article
Journal of Interventional Cardiology, ISSN 0896-4327, 10/2017, Volume 30, Issue 5, pp. 488 - 490
Journal Article