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1. Full Text So Many Correlated Tests, So Little Time! Rapid Adjustment of P Values for Multiple Correlated Tests
by Conneely, Karen N and Boehnke, Michael
American journal of human genetics, ISSN 0002-9297, 2007, Volume 81, Issue 6, pp. 1158 - 1168
Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Fundamental and applied biological sciences. Psychology | General aspects. Genetic counseling | Medical genetics | Biological and medical sciences | Molecular and cellular biology | Genetics of eukaryotes. Biological and molecular evolution | Medical sciences | Genetic Predisposition to Disease | Genetic Testing | Hepatocyte Nuclear Factor 1-alpha - genetics | Computer Simulation | Diabetes Mellitus, Type 2 - genetics | Humans | Finland | Polymorphism, Single Nucleotide - genetics | Models, Genetic | Models, Statistical | Case-Control Studies | Linkage Disequilibrium | Permutations | Statistical hypothesis testing | Usage | Research | Human genome | Genetics | Accuracy | Simulation | Correlation analysis | Index Medicus
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2. Full Text Comprehensive Association Study of Type 2 Diabetes and Related Quantitative Traits With 222 Candidate Genes
by Kyle J. Gaulton and Cristen J. Willer and Yun Li and Laura J. Scott and Karen N. Conneely and Anne U. Jackson and William L. Duren and Peter S. Chines and Narisu Narisu and Lori L. Bonnycastle and Jingchun Luo and Maurine Tong and Andrew G. Sprau and Elizabeth W. Pugh and Kimberly F. Doheny and Timo T. Valle and Gonçalo R. Abecasis and Jaakko Tuomilehto and Richard N. Bergman and Francis S. Collins and Michael Boehnke and Karen L. Mohlke
Diabetes (New York, N.Y.), ISSN 0012-1797, 11/2008, Volume 57, Issue 11, pp. 3136 - 3144
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Glucose Transporter Type 2 - genetics | Genetic Predisposition to Disease - genetics | Quantitative Trait, Heritable | Diabetes Mellitus, Type 2 - genetics | Gene Frequency | Humans | Middle Aged | Pyrophosphatases - genetics | Genotype | Male | Potassium Channels, Inwardly Rectifying - genetics | Phosphoric Diester Hydrolases - genetics | Genes, p53 - genetics | Nuclear Respiratory Factor 1 - genetics | Finland | Adult | Female | Aged | Polymorphism, Single Nucleotide | Type 2 diabetes | Physiological aspects | Genetic aspects | Research | Diagnosis | Risk factors | Index Medicus | Abridged Index Medicus | Genetics
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3. Full Text A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data
by Feng, Hao and Conneely, Karen N and Wu, Hao
Nucleic acids research, ISSN 0305-1048, 4/2014, Volume 42, Issue 8, pp. e69 - e69
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | DNA Methylation | Animals | Nucleotides - analysis | Bayes Theorem | Embryonic Development - genetics | CpG Islands | Mice | Genetic Loci | Models, Statistical | Sequence Analysis, DNA - methods | Index Medicus | Methods Online
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4. Full Text Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type
by Smith, Alicia K and Kilaru, Varun and Kocak, Mehmet and Almli, Lynn M and Mercer, Kristina B and Ressler, Kerry J and Tylavsky, Frances A and Conneely, Karen N
BMC genomics, ISSN 1471-2164, 02/2014, Volume 15, Issue 1, pp. 145 - 145
Brain | Biomarker | Gene regulation | Race | DNA methylation | Inter-individual variation | Ancestry | Developmental stage | meQTL | mQTL | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Genome-Wide Association Study | Epigenesis, Genetic | Humans | Middle Aged | Gene Expression Regulation | Male | Gene-Environment Interaction | Organ Specificity - genetics | DNA Methylation | CpG Islands | Adult | Female | Polymorphism, Single Nucleotide | Quantitative Trait Loci | Cluster Analysis | Evolution, Molecular | African Americans | Single nucleotide polymorphisms | Methylation | Analysis | Genomics | Studies | Genes | Index Medicus
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5. Full Text An integrated -omics analysis of the epigenetic landscape of gene expression in human blood cells
by Kennedy, Elizabeth M and Goehring, George N and Nichols, Michael H and Robins, Chloe and Mehta, Divya and Klengel, Torsten and Eskin, Eleazar and Smith, Alicia K and Conneely, Karen N
BMC genomics, ISSN 1471-2164, 06/2018, Volume 19, Issue 1, pp. 476 - 476
DNA methylation | Gene expression | Transcriptional regulation | Blood cells | Genetics & Heredity | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Epigenesis, Genetic | Genomics | Humans | Middle Aged | Blood Cells - metabolism | Male | Gene Expression Profiling | Young Adult | DNA Methylation | Adolescent | CpG Islands | Adult | Female | Aged | Gene Ontology | Cohort Studies | Epigenetic inheritance | Analysis | Genetic transcription | Research | Methylation | Enrichment | Chromatin | Genes | Insulators | Data processing | Genomes | Regulatory sequences | Data mining | Ribonucleic acid--RNA | Blood | Promoters | Studies | Enhancers | Biological effects | MicroRNAs | Atherosclerosis | Epigenetics | miRNA | Binding sites | Deoxyribonucleic acid--DNA | Index Medicus
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6. Full Text Screening of 134 Single Nucleotide Polymorphisms (SNPs) Previously Associated With Type 2 Diabetes Replicates Association With 12 SNPs in Nine Genes
by Cristen J. Willer and Lori L. Bonnycastle and Karen N. Conneely and William L. Duren and Anne U. Jackson and Laura J. Scott and Narisu Narisu and Peter S. Chines and Andrew Skol and Heather M. Stringham and John Petrie and Michael R. Erdos and Amy J. Swift and Sareena T. Enloe and Andrew G. Sprau and Eboni Smith and Maurine Tong and Kimberly F. Doheny and Elizabeth W. Pugh and Richard M. Watanabe and Thomas A. Buchanan and Timo T. Valle and Richard N. Bergman and Jaakko Tuomilehto and Karen L. Mohlke and Francis S. Collins and Michael Boehnke
Diabetes (New York, N.Y.), ISSN 0012-1797, 01/2007, Volume 56, Issue 1, pp. 256 - 264
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Body Mass Index | Fasting | Genetic Testing | Blood Glucose - analysis | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Infant | Male | Chromosome Mapping | Insulin - blood | Female | Aged | Polymorphism, Single Nucleotide | Type 2 diabetes | Care and treatment | Single nucleotide polymorphisms | Diagnosis | Medical screening | Health aspects | Index Medicus | Abridged Index Medicus
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7. Full Text Genetic Variation Near the Hepatocyte Nuclear Factor-4α Gene Predicts Susceptibility to Type 2 Diabetes
by Kaisa Silander and Karen L. Mohlke and Laura J. Scott and Erin C. Peck and Pablo Hollstein and Andrew D. Skol and Anne U. Jackson and Panagiotis Deloukas and Sarah Hunt and George Stavrides and Peter S. Chines and Michael R. Erdos and Narisu Narisu and Karen N. Conneely and Chun Li and Tasha E. Fingerlin and Sharanjeet K. Dhanjal and Timo T. Valle and Richard N. Bergman and Jaakko Tuomilehto and Richard M. Watanabe and Michael Boehnke and Francis S. Collins
Diabetes (New York, N.Y.), ISSN 0012-1797, 04/2004, Volume 53, Issue 4, pp. 1141 - 1149
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Predictive Value of Tests | Genetic Predisposition to Disease - genetics | Risk Assessment | United States | Diabetes Mellitus, Type 2 - genetics | Humans | Genotype | Chromosome Mapping | Genetic Markers | Phosphoproteins - genetics | Transcription Factors - genetics | Lod Score | DNA - blood | DNA - genetics | Genetic Variation | Diabetes Mellitus, Type 2 - blood | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors | Finland | Polymorphism, Single Nucleotide - genetics | Family | Hepatocyte Nuclear Factor 4 | Odds Ratio | Chromosomes, Human, Pair 20 - genetics | DNA-Binding Proteins | Index Medicus | Abridged Index Medicus
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8. Full Text Testing evolutionary models of senescence: traditional approaches and future directions
by Robins, Chloe and Conneely, Karen N
Human genetics, ISSN 0340-6717, 12/2014, Volume 133, Issue 12, pp. 1451 - 1465
Human Genetics | Gene Function | Molecular Medicine | Biomedicine | Metabolic Diseases | Life Sciences & Biomedicine | Genetics & Heredity | Science & Technology | Biological Evolution | Genetic Variation | DNA Methylation | Animals | Aging - genetics | Species Specificity | Epigenesis, Genetic | Humans | Mutation Rate | Genetic Pleiotropy | Models, Genetic | Longevity - genetics | Methylation | Evolution | Analysis | Index Medicus
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9. Full Text A Genome-Wide Association Study of Type 2 Diabetes in Finns Detects Multiple Susceptibility Variants
by Laura J. Scott and Karen L. Mohlke and Lori L. Bonnycastle and Cristen J. Willer and Yun Li and William L. Duren and Michael R. Erdos and Heather M. Stringham and Peter S. Chines and Anne U. Jackson and Ludmila Prokunina-Olsson and Chia-Jen Ding and Amy J. Switt and Narisu Narisu and Tianle Hu and Randall Pruim and Rui Xiao and Xiao-Yi Li and Karen N. Conneely and Nancy L. Riebow and Andrew G. Sprau and Maurine Tong and Peggy P. White and Kurt N. Hetrick and Michael W. Barnhart and Craig W. Bark and Janet L. Goldstein and Lee Watkins and Fang Xiang and Jouko Saramies and Thomas A. Buchanan and Richard M. Watanabe and Timo T. Valle and Leena Kinnunen and Gonçalo R. Abecasis and Elizabeth W. Pugh and Kimberly F. Doheny and Richard N. Bergman and Jaakko Tuomilehto and Francis S. Collins and Michael Boehnke
Science (American Association for the Advancement of Science), ISSN 0036-8075, 6/2007, Volume 316, Issue 5829, pp. 1341 - 1345
Hep G2 cells | Diabetes mellitus | Medical genetics | Genetic loci | Reports | Diabetes | Type 2 diabetes mellitus | Insulin | Chromosomes | Human genetics | Genotypes | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Biological and medical sciences | Endocrinopathies | Etiopathogenesis. Screening. Investigations. Target tissue resistance | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | DNA, Intergenic | Insulin-Like Growth Factor Binding Proteins - genetics | Genetic Predisposition to Disease | Meta-Analysis as Topic | Introns | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Genotype | Logistic Models | Male | Chromosome Mapping | Chromosomes, Human, Pair 11 - genetics | Genes, p16 | Case-Control Studies | Finland | Female | Polymorphism, Single Nucleotide | Genome, Human | Type 2 diabetes | Genetic aspects | Research | Risk factors | Genotype & phenotype | Population genetics | Genomics | Index Medicus
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