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Environmental science & technology, ISSN 0013-936X, 1/2018, Volume 52, Issue 2, pp. 839 - 849
Cumulative risk assessment (CRA) methods promote the use of a conceptual site model (CSM) to apportion exposures and integrate risk from multiple stressors.... 
Adverse Outcome Pathway (AOP) | Ecotoxicology | Aggregate exposure | Cumulative risk assessment | Human Health
Journal Article
Risk Analysis, ISSN 0272-4332, 04/2009, Volume 29, Issue 4, pp. 480 - 481
Journal Article
Toxicological Sciences, ISSN 1096-6080, 01/2004, Volume 77, Issue 1, pp. 151 - 157
Dose-response curves for the first interaction of a chemical with a biochemical target molecule are usually monotonic; i.e., they increase or decrease over the... 
Mechanisms | Hormesis | Models | Dose-response relationship | models | FORESTOMACH | STIMULATION | CHEMICAL CARCINOGENESIS | DNA-DAMAGE | TUMOR-INDUCTION | REPAIR | CAFFEIC ACID | GROWTH | TOXICOLOGY | dose-response relationship | hormesis | mechanisms | Dose-Response Relationship, Drug | Animals | Risk Assessment | Models, Biological | Humans | Rats | Xenobiotics - toxicity | Xenobiotics - pharmacokinetics | Index Medicus
Journal Article
Journal Article
Toxicological Sciences, ISSN 1096-6080, 05/2010, Volume 115, Issue 1, pp. 51 - 65
The differentiation of B cells into antibody-secreting plasma cells upon antigen stimulation, a crucial step in the humoral immune response, is disrupted by... 
Cellular reprogramming | TCDD | Coupled feedback loops | Dedifferentiation | Immunotoxicity | Bistability | LINEAGE-COMMITMENT | bistability | LYMPHOCYTE TERMINAL DIFFERENTIATION | cellular reprogramming | TRANSCRIPTIONAL REPRESSION | dedifferentiation | coupled feedback loops | SIGNAL-TRANSDUCTION | ARYL-HYDROCARBON RECEPTOR | EMBRYONIC STEM-CELLS | LIVED PLASMA-CELLS | GENE-EXPRESSION | immunotoxicity | POSITIVE-FEEDBACK | TOXICOLOGY | NEGATIVE FEEDBACK | Genes, Switch - drug effects | Humans | Transcriptional Activation - drug effects | Systems Biology | DNA-Binding Proteins - metabolism | Plasma Cells - drug effects | Cell Differentiation - genetics | Environmental Pollutants - toxicity | PAX5 Transcription Factor - metabolism | Repressor Proteins - metabolism | Cell Dedifferentiation - drug effects | PAX5 Transcription Factor - genetics | Repressor Proteins - genetics | DNA-Binding Proteins - genetics | B-Lymphocytes - drug effects | Animals | B-Lymphocytes - immunology | Cell Differentiation - drug effects | Models, Biological | Lipopolysaccharides - pharmacology | Polychlorinated Dibenzodioxins - toxicity | Feedback, Physiological - drug effects | Mice | Feedback, Physiological - physiology | Plasma Cells - immunology | Positive Regulatory Domain I-Binding Factor 1 | Proto-Oncogene Proteins c-bcl-6 | Index Medicus | Immunotoxicology
Journal Article
Toxicology and Applied Pharmacology, ISSN 0041-008X, 04/2013, Volume 268, Issue 1, pp. 17 - 26
Journal Article
Toxicology Letters, ISSN 0378-4274, 08/2013, Volume 221, pp. S3 - S3
Journal Article
Journal Article