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American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 02/2019, Volume 199, Issue 4, pp. 478 - 488
Rationale: Polymorphisms on chromosome 17q21 confer the major genetic susceptibility to childhood-onset asthma. Risk alleles positively correlate with ORMDL3... 
Inflammation | ORMDL3 | Childhood asthma | ICAM1 | METAANALYSIS | SUSCEPTIBILITY | RECEPTOR | RISK | childhood asthma | LESSONS | OBESITY | inflammation | RESPIRATORY SYSTEM | INFECTION | PROTEINS | EXPRESSION | ASSOCIATION | CRITICAL CARE MEDICINE | Proteins | Tuberculosis | Cytokines | Tumor necrosis factor-TNF | Diabetes | Gene expression | Kinases | Endoplasmic reticulum | Asthma
Journal Article
Nucleic acids research, 04/2014, Volume 42, Issue 6, p. 3515
Differences in methylation across tissues are critical to cell differentiation and are key to understanding the role of epigenetics in complex diseases. In... 
DNA Methylation | Atrial Appendage - metabolism | Humans | CpG Islands | Female | Male | Models, Statistical | Child | Leukocytes - metabolism | Cell Line, Transformed | Arteries - metabolism
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2010, Volume 5, Issue 1, pp. e8578 - e8578
Journal Article
Nature Genetics, ISSN 1061-4036, 10/2007, Volume 39, Issue 10, pp. 1202 - 1207
Journal Article
American journal of respiratory and critical care medicine, ISSN 1073-449X, 10/2014, Volume 190, Issue 8, pp. 906 - 913
Journal Article
by Demenais, Florence and Margaritte-Jeannin, Patricia and Barnes, Kathleen C and Cookson, William O. C and Altmüller, Janine and Ang, Wei and Barr, R. Graham and Beaty, Terri H and Becker, Allan B and Beilby, John and Bisgaard, Hans and Bjornsdottir, Unnur Steina and Bleecker, Eugene and Bønnelykke, Klaus and Boomsma, Dorret I and Bouzigon, Emmanuelle and Brightling, Christopher E and Brossard, Myriam and Brusselle, Guy G and Burchard, Esteban and Burkart, Kristin M and Bush, Andrew and Chan-Yeung, Moira and Chung, Kian Fan and Couto Alves, Alexessander and Curtin, John A and Custovic, Adnan and Daley, Denise and De Jongste, Johan C and Del-Rio-Navarro, Blanca E and Donohue, Kathleen M and Duijts, Liesbeth and Eng, Celeste and Eriksson, Johan G and Farrall, Martin and Fedorova, Yuliya and Feenstra, Bjarke and Ferreira, Manuel A and Freidin, Maxim B and Gajdos, Zofia and Gauderman, Jim and Gehring, Ulrike and Geller, Frank and Genuneit, Jon and Gharib, Sina A and Gilliland, Frank and Granell, Raquel and Graves, Penelope E and Gudbjartsson, Daniel F and Haahtela, Tari and Heckbert, Susan R and Heederik, Dick and Heinrich, Joachim and Heliövaara, Markku and Henderson, John and Himes, Blanca E and Hirose, Hiroshi and Hirschhorn, Joel N and Hofman, Albert and Holt, Patrick and Hottenga, Jouke and Hudson, Thomas J and Hui, Jennie and Imboden, Medea and Ivanov, Vladimir and Jaddoe, Vincent W. V and James, Alan and Janson, Christer and Jarvelin, Marjo-Riitta and Jarvis, Deborah and Jones, Graham and Jonsdottir, Ingileif and Jousilahti, Pekka and Kabesch, Michael and Kähönen, Mika and Kantor, David B and Karunas, Alexandra S and Khusnutdinova, Elza and Koppelman, Gerard H and Kozyrskyj, Anita L and Kreiner, Eskil and Kubo, Michiaki and Kumar, Rajesh and Kumar, Ashish and Kuokkanen, Mikko and Lahousse, Lies and Laitinen, Tarja and Laprise, Catherine and Lathrop, Mark and Lau, Susanne and Lee, Young-Ae and Lehtimäki, Terho and Letort, Sébastien and Levin, Albert M and Li, Guo and Liang, Liming and Loehr, Laura R and London, Stephanie J and Loth, Daan W and Manichaikul, Ani and ... and Australian Asthma Genetics Consort and Australian Asthma Genetics Consortium (AAGC) collaborators and Medicinska fakulteten and Medicinska och farmaceutiska vetenskapsområdet and Lung- allergi- och sömnforskning and Medicinska och farmaceutiska vetenskapsområdet, centrumbildningar mm and Uppsala universitet and Institutionen för medicinska vetenskaper and Centrum för klinisk forskning i Sörmland (CKFD)
Nature Genetics, ISSN 1061-4036, 01/2018, Volume 50, Issue 1, pp. 42 - 50
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 11/2013, Volume 188, Issue 10, pp. 1224 - 1231
Rationale: Rhinovirus infection is followed by significantly increased frequencies of positive, potentially pathogenic sputum cultures in chronic obstructive... 
Bacteria | Chronic obstructive pulmonary disease | Microbiome | Rhinovirus | NONSMOKERS | bacteria | SEQUENCES | COMMUNITIES | rhinovirus | microbiome | GRADIENT GEL-ELECTROPHORESIS | RESPIRATORY SYSTEM | INFLAMMATION | SMOKERS | DIVERSITY | INFECTION | chronic obstructive pulmonary disease | 16S RIBOSOMAL-RNA | COPD |