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Science, ISSN 0036-8075, 9/2006, Volume 313, Issue 5794, pp. 1781 - 1784
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, p. e0118947
Journal Article
EMBO reports, ISSN 1469-221X, 09/2006, Volume 7, Issue 9, pp. 940 - 946
We have generated a novel transgenic mouse model on a C57BL/6J genetic background that coexpresses KM670/671NL mutated amyloid precursor protein and L166P... 
ageing | microglia transgenic mouse model | amyloid | Alzheimer | Scientific Report
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2003, Volume 100, Issue 24, pp. 14193 - 14198
Journal Article
The FEBS Journal, ISSN 1742-464X, 02/2014, Volume 281, Issue 3, pp. 862 - 876
Cellular prion protein (PrPC) misfolds to form infectivity‐associated scrapie prion protein and generates C‐terminal fragments C1 and C2 in healthy and... 
Doppel | endoproteolysis | ADAM | Shadoo | prion protein | Prion protein | Endoproteolysis | ALPHA-CLEAVAGE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ADAM10 | HUMAN DOPPEL | GENE | CELLULAR PRION | SHADOO PROTEINS | MICE | KNOCKOUT | EXPRESSION | N-TERMINAL REGION | Testis - metabolism | Prions - genetics | Glycoproteins - metabolism | Brain - enzymology | Male | Recombinant Fusion Proteins - metabolism | PrPC Proteins - chemistry | Brain - metabolism | Nerve Tissue Proteins - chemistry | Proteolysis | Testis - enzymology | Neurons - metabolism | PrPC Proteins - metabolism | Glycoproteins - chemistry | PrPC Proteins - genetics | Peptide Fragments - genetics | Glycoproteins - genetics | Protein Structure, Tertiary | Cell Line | Endopeptidases - metabolism | Prions - metabolism | Rabbits | Peptide Fragments - metabolism | Mice, Transgenic | Mutant Proteins - metabolism | Glycosylation | Prions - chemistry | Recombinant Fusion Proteins - chemistry | Nerve Tissue Proteins - genetics | GPI-Linked Proteins - metabolism | Nerve Tissue Proteins - metabolism | Peptide Fragments - chemistry | Animals | GPI-Linked Proteins - chemistry | Mutant Proteins - chemistry | Neurons - enzymology | Mice | Protein Processing, Post-Translational | GPI-Linked Proteins - genetics | Gene mutations | Proteases | Prions | Glycoproteins | Cellular biology | Molecular biology | Index Medicus
Journal Article
Journal Article
PLOS PATHOGENS, ISSN 1553-7366, 11/2011, Volume 7, Issue 11, p. e1002391
During prion infections of the central nervous system (CNS) the cellular prion protein, PrPC, is templated to a conformationally distinct form, PrPSc. Recent... 
MOUSE-BRAIN | STRAINS | PROTEIN | ALZHEIMERS-DISEASE | MICROBIOLOGY | CULTURED-CELLS | CUPRIZONE TOXICITY | RESISTANT | VIROLOGY | GENE | SCRAPIE INCUBATION-TIME | PARASITOLOGY | TRANSGENIC MICE | Medical research | Food contamination & poisoning | Brain research | Pathogenesis | Protein folding | Prions | Creutzfeldt-Jakob disease | Infections
Journal Article
Neurobiology of Aging, ISSN 0197-4580, 05/2013, Volume 34, Issue 5, pp. 1416 - 1425
Familial British and familial Danish dementia (FDD) are progressive neurodegenerative disorders characterized by cerebral deposition of the amyloidogenic... 
Amyloidogenesis | Brain | Glutamic acid | Animal models | Deposits | Neurodegenerative diseases | Toxicity | Antibodies | Nervous system | Neuroblastoma cells | Synaptic transmission | Aging | Dementia disorders | Amyloid | Alzheimer's disease | Hippocampus | Plaques
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2005, Volume 102, Issue 25, pp. 8972 - 8977
Journal Article